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Zycel (Celecoxib)

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Zycel is an NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis. Zycel is indicated for symptomatic treatment of adult osteoarthritis (OA) and adult rheumatoid arthritis (RA).

Other names for this medication:
Celact, Celcib, Celcox, Celebix, Celecap, Celecoxib, Celedol, Celemax, Celetop, Celexax, Celfast, Celib, Celira, Cobix, Colcibra, Coxib, Eloxib, Orthocel, Orthocell, Revibra, Sionara, Zecoxib, Zycel

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Also known as: Celecoxib


Zycel (celecoxib) is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.

Zycel is used to treat pain or inflammation caused by many conditions such as arthritis, ankylosing spondylitis, and menstrual pain.

Zycel is used to treat juvenile rheumatoid arthritis in children who are at least 2 years old. It is also used in the treatment of hereditary polyps in the colon.


Usual Adult Dose for Pain:

Acute pain: 400 mg initially, followed by 200 mg if needed on the first day. Then, 200 mg twice daily as needed.

Usual Adult Dose for Dysmenorrhea:

400 mg initially, followed by 200 mg if needed on the first day. Then, 200 mg twice daily as needed.

Usual Adult Dose for Osteoarthritis:

200 mg orally once daily or 100 mg orally twice daily.

Usual Adult Dose for Rheumatoid Arthritis:

100 to 200 mg orally twice daily.

Usual Adult Dose for Familial Adenomatous Polyposis:

400 mg orally twice daily with food.

Usual Adult Dose for Ankylosing Spondylitis:

200 mg orally once daily or 100 mg orally twice daily. If after 6 weeks of therapy no results are observed, a trial dose of 400 mg orally daily may be worthwhile. If no response is seen after 6 weeks, consideration should be given to alternate treatment options.

Usual Pediatric Dose for Juvenile Rheumatoid Arthritis:

2 years or older: 10 to less than or equal to 25 kg: 50 mg orally twice daily Greater than 25 kg: 100 mg orally twice daily

Detailed Zycel dosage information


If you overdose Generic Zycel and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Zycel are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Zycel if you are allergic to Generic Zycel components or to aspirin. Do not take Generic Zycel if you are pregnant, planning to become pregnant. It is unknown if Generic Zycel is excreted in breast milk. Avoid breast-feeding. Generic Zycel can't be given to children under 2 years. Generic Zycel can't be given to patients who experience bypass surgery. Do not use allergy and pain medicines at the same time with Generic Zycel. Try to be careful with Generic Zycel in case of using such medications as (Mavik), quinapril (Accupril), ACE inhibitor (captopril (Capoten), benazepril (Lotensin), lisinopril (Zestril, Prinivil), ramipril (Altace), enalapril (Vasotec), fosinopril (Monopril), moexipril (Univasc), perindopril (Aceon), blood thinner as warfarin (Coumadin), aspirin or other NSAIDs (mefenamic acid (Ponstel), etodolac (Lodine), diclofenac (Voltaren), ibuprofen (Advil, Motrin), piroxicam (Feldene),naproxen (Aleve, Naprosyn), flurbiprofen (Ansaid), ketorolac (Toradol), ketoprofen (Orudis), nabumetone (Relafen), meloxicam (Mobic)), methotrexate (Rheumatrex, Trexall), diuretics (furosemide (Lasix)), lithium (Eskalith, Lithobid). Be careful with Generic Zycel in case of having liver, heart or kidney disease, asthma, high blood pressure, stroke, stomach ulcers, bleeding or blood clotting disorder, congestive heart failure, epilepsy. Be careful with sunbeams. Generic Zycel makes skin sensitive to sunlight. Protect skin from the sun. Avoid alcohol. It can be dangerous to stop Generic Zycel taking suddenly.

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The disposal problem due to non-degradable petroleum-based plastics has raised the demand for biodegradable polymers. In regions of high HIV prevalence in sub-Saharan Africa, HIV-affected couples require multipurpose prevention technologies (MPTs) to enhance their reproductive healthcare options beyond contraception and prevention of HIV/sexually transmitted infections (STIs) to include assistance in childbearing. To investigate the method and effectiveness of perforator flaps in repairing soft tissue defects of extremities. The current investigation analyzed data from a pilot randomized controlled trial comparing a 12-session yoga intervention with an assessment control for women age 18 to 65 years with PTSD. It was found that age at first marriage and birth of the first child as well as the number of abortions and parity adjusted for age at first birth were associated with the breast cancer risk, whereas lactation was not. We are also setting forth the update factor for determining the rate-of-increase limits (target amounts) for hospitals excluded from the prospective payment system. Effect of altitude and sun rays on gastric passage and intestinal absorption of glucose solutions in the rat. Taking into account the multivalley nature of the conduction band in silicon and germanium, we show that the spin-flip amplitude is dominated by short-range scattering off the central-cell potential of impurities after which the electron is transferred to a valley on a different axis in k space. Accumulating evidence has shown that the FV-EUS can be used instead of the standard CLA-EUS scope for routine fine needle aspiration, with extremely good performance for subepithelial lesions and for difficult to reach locations. In contrast, a significant difference was found between the glycoprofiles of salivary TIMP-1 and plasma TIMP-1.

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The management of headache following accidental dural puncture in obstetric patients. The degree of this segregation distortion is obvious in male offspring and is possibly of the same magnitude for female offspring. Decreasing hospitalization and in-hospital mortality related to cholangitis in the United States. Prophylactic ranitidine in experimental fetal distress: acute phase effects on the fetal stomach. On the positive side, we identify islands of tractability for the problem, by focusing on instances with specific structure of haplotype sharing among the input genotypes. Foreign body (catheter) in the uterine cavity during pregnancy without interruption of gestation.

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Fractal quantification of the microvasculature heterogeneity in cutaneous melanoma. (64)Cu-labeled peptide for PET of breast carcinomas expressing the Thomsen-Friedenreich carbohydrate antigen. The minimal group received admission history, medication reconciliation, patient education, discharge medication list and medication recommendations to inpatient team. This study further defines the influence of GDF-5 on rat ATFs through its action on the expression of genes that are associated with tendon ECM. Histology for all tumors were either oligodendroglioma or had features of oligodendroglioma. Sixty-nine patients with pink xanax pills mg histopathologically proven liver metastases from NET and 69 patients with known liver metastases of other origin underwent MRI of the liver using a 1.5 T MR-scanner. Pretreatment computed tomographic (CT) images of 42 patients with cervical cancer were evaluated to locate the aortic bifurcation and the subsequent common iliac lymph drainage. We have demonstrated a negative correlation between superoxide anion production and cell density in the peritoneal cavity in macrophages challenged with PMA.

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The available evidence will be summarized and discussed to provide a basis for decision-making for patients and healthcare professionals. To determine the most important predictors of inhospital mortality that could be assessed in geriatric patients presenting with ischemic stroke at admission to the emergency department(ED). Quantitative impairments in carbohydrate-containing components of glycoproteins are discussed. These changes in mast cells can be used as a criterion of chronic myocardial ischemia. Abnormal components in cells can be eliminated through upregulating cell autophagy or inhibiting autophagy after ischemic brain injury, resulting in a dynamic balance of substances in cells. Cornu Ammonis of the dog: a rudimentary CA2 field is only present in a small part of the dorsal division, and is absent in the ventral division of the cornu Ammonis. We studied the effect of argon laser trabeculoplasty (ALT) on medically controlled, pressure-stable glaucoma patients to verify whether it is possible to reduce ocular hypotensive medication can ativan treat alcohol withdrawal after ALT while keeping intraocular pressure levels similar to those observed before the procedure. Subcapital fractures of the femur treated with two thin Smith-Petersen nails.

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Regardless of the means used to estimate blood loss, clinical observation of the patient with frequent assessment of cardiovascular status is that basis of total management. Cross-linking was safe and an effective therapeutical option for progressive keratoconus. These data were obtained immediately after cardiopulmonary bypass and were compared with data obtained before hospital discharge (transthoracic echocardiogram 1) and 6 to 12 months after surgery (transthoracic echocardiogram 2). Adaptation of passive rat left ventricle in diastolic dysfunction. We describe a case example of culture change and definitions of wellness at William Beaumont Hospitals, Troy Family Medicine Residency Program, a community-based, university-affiliated program in suburban Detroit, Michigan. Detection of Helicobacter pylori in raw bovine milk by fluorescence in situ hybridization (FISH). A different focus amoxil daily dose must be established if we are to control both disease and our health-care budget. A strong negative transcriptional regulatory region between the human cytomegalovirus UL127 gene and the major immediate-early enhancer.

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Aflatoxin M1 absorption and cytotoxicity on human intestinal in vitro model. A difficult to diagnose subgroup of CMS is characterised by proximal muscle weakness and fatigue while ocular and facial involvement is only minimal. This paper describes the CEM and reviews the research so-far in relation to the model. The anatomic, neural and endocrine systems that support these symptomatic functions and dysfunctions span the range from the urogenital smooth muscle to the hypothalamus, the bladder sensory output to the micturition centre and growth factors to androgens. The objective of this formative research was to explore the acceptability and feasibility of changing housekeeping behaviors as a low-cost approach that may reduce childhood lead exposure in Johannesburg, South Africa. In those species with a dorsal sac, its close association with the pineal-end-vesicle suggests a functional relationship between the two structures. Batimastat had a dose-related effect on embryo growth and viability following 48 h in culture, with significant inhibition at 1.0 microM concentration. Profilaggrin is proteolytically processed into individual domains during the terminal differentiation.

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Comparison of influenza outbreaks in the Republic of Kazakhstan and Russia induced by 2009 yearly new variant of A(H1N1) influenza virus. Actions to promote cycling in cities should go together with improving road safety. The E23K gene polymorphism of Kir6.2 gene was analyzed by PCR-restriction site polymorphism (PCR-RSP) methods in 101 controls and 119 CHD patients. In this review the authors focus on biological applications and technologies that utilise two types of related plasmonic phenomonae: localised surface plasmon resonance (LSPR) spectroscopy and surface-enhanced Raman spectroscopy (SERS). Several regulators (mammalian target of rapamycin, serum response factor, atrogin-1, myostatin, etc.) seem to modulate protein synthesis and degradation or transcription of muscle-specific genes during both sarcopenia and muscular dystrophy. We report here the identification of a W-linked marker in the ostrich (Struthio camelus) which allows gender diagnosis in chicks or juvenile birds. The rate of grading concordance and the effect of different variables on the concordance rate was determined. The impact of osteoblastic differentiation on osteosarcomagenesis in the mouse. The experiments were designed with a 2(5-1) reduced factorial design and analyzed in terms of multivariate regression models.

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Imaging patterns of hepatic steatosis on multidetector CT: pearls and pitfalls. Direction and magnitude of nicotine effects on the fMRI BOLD response are related to nicotine effects on behavioral performance. Mutual cooperation, collaboration and by integrating TH into primary oral health care services needs to be increased. Women who reported recent vibrator use with other women had higher mean sexual functioning scores than women who reported no vibrator use or vibrator use only during masturbation. Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B. Conclusions and future directions for periodic reporting on the use of selected clinical preventive services to improve the health of infants, children, and adolescents--United States. These results report novel TUDCA anti-inflammatory actions, with potential therapeutic implications for neurodegenerative diseases, including retinitis pigmentosa. The plaster cast immobilization has a greater effect on the homoeostasis of the nucleic acids of the tonic muscles than in the case of the tetanic muscles.

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