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Zycel (Celecoxib)
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Zycel

Zycel is an NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis. Zycel is indicated for symptomatic treatment of adult osteoarthritis (OA) and adult rheumatoid arthritis (RA).

Other names for this medication:
Celact, Celcib, Celcox, Celebix, Celecap, Celecoxib, Celedol, Celemax, Celetop, Celexax, Celfast, Celib, Celira, Cobix, Colcibra, Coxib, Eloxib, Orthocel, Orthocell, Revibra, Sionara, Zecoxib, Zycel

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Also known as: Celecoxib

Description

Zycel (celecoxib) is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.

Zycel is used to treat pain or inflammation caused by many conditions such as arthritis, ankylosing spondylitis, and menstrual pain.

Zycel is used to treat juvenile rheumatoid arthritis in children who are at least 2 years old. It is also used in the treatment of hereditary polyps in the colon.

Dosage

Usual Adult Dose for Pain:

Acute pain: 400 mg initially, followed by 200 mg if needed on the first day. Then, 200 mg twice daily as needed.

Usual Adult Dose for Dysmenorrhea:

400 mg initially, followed by 200 mg if needed on the first day. Then, 200 mg twice daily as needed.

Usual Adult Dose for Osteoarthritis:

200 mg orally once daily or 100 mg orally twice daily.

Usual Adult Dose for Rheumatoid Arthritis:

100 to 200 mg orally twice daily.

Usual Adult Dose for Familial Adenomatous Polyposis:

400 mg orally twice daily with food.

Usual Adult Dose for Ankylosing Spondylitis:

200 mg orally once daily or 100 mg orally twice daily. If after 6 weeks of therapy no results are observed, a trial dose of 400 mg orally daily may be worthwhile. If no response is seen after 6 weeks, consideration should be given to alternate treatment options.

Usual Pediatric Dose for Juvenile Rheumatoid Arthritis:

2 years or older: 10 to less than or equal to 25 kg: 50 mg orally twice daily Greater than 25 kg: 100 mg orally twice daily

Detailed Zycel dosage information

Overdose

If you overdose Generic Zycel and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Zycel are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Generic Zycel if you are allergic to Generic Zycel components or to aspirin. Do not take Generic Zycel if you are pregnant, planning to become pregnant. It is unknown if Generic Zycel is excreted in breast milk. Avoid breast-feeding. Generic Zycel can't be given to children under 2 years. Generic Zycel can't be given to patients who experience bypass surgery. Do not use allergy and pain medicines at the same time with Generic Zycel. Try to be careful with Generic Zycel in case of using such medications as (Mavik), quinapril (Accupril), ACE inhibitor (captopril (Capoten), benazepril (Lotensin), lisinopril (Zestril, Prinivil), ramipril (Altace), enalapril (Vasotec), fosinopril (Monopril), moexipril (Univasc), perindopril (Aceon), blood thinner as warfarin (Coumadin), aspirin or other NSAIDs (mefenamic acid (Ponstel), etodolac (Lodine), diclofenac (Voltaren), ibuprofen (Advil, Motrin), piroxicam (Feldene),naproxen (Aleve, Naprosyn), flurbiprofen (Ansaid), ketorolac (Toradol), ketoprofen (Orudis), nabumetone (Relafen), meloxicam (Mobic)), methotrexate (Rheumatrex, Trexall), diuretics (furosemide (Lasix)), lithium (Eskalith, Lithobid). Be careful with Generic Zycel in case of having liver, heart or kidney disease, asthma, high blood pressure, stroke, stomach ulcers, bleeding or blood clotting disorder, congestive heart failure, epilepsy. Be careful with sunbeams. Generic Zycel makes skin sensitive to sunlight. Protect skin from the sun. Avoid alcohol. It can be dangerous to stop Generic Zycel taking suddenly.

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The disposal problem due to non-degradable petroleum-based plastics has raised the demand for biodegradable polymers. In regions of high HIV prevalence in sub-Saharan Africa, HIV-affected couples require multipurpose prevention technologies (MPTs) to enhance their reproductive healthcare options beyond contraception and prevention of HIV/sexually transmitted infections (STIs) to include assistance in childbearing. To investigate the method and effectiveness of perforator flaps in repairing soft tissue defects of extremities. The current investigation analyzed data from a pilot randomized controlled trial comparing a 12-session yoga intervention with an assessment control for women age 18 to 65 years with PTSD. It was found that age at first marriage and birth of the first child as well as the number of abortions and parity adjusted for age at first birth were associated with the breast cancer risk, whereas lactation was not. We are also setting forth the update factor for determining the rate-of-increase limits (target amounts) for hospitals excluded from the prospective payment system. Effect of altitude and sun rays on gastric passage and intestinal absorption of glucose solutions in the rat. Taking into account the multivalley nature of the conduction band in silicon and germanium, we show that the spin-flip amplitude is dominated by short-range scattering off the central-cell potential of impurities after which the electron is transferred to a valley on a different axis in k space. Accumulating evidence has shown that the FV-EUS can be used instead of the standard CLA-EUS scope for routine fine needle aspiration, with extremely good performance for subepithelial lesions and for difficult to reach locations. In contrast, a significant difference was found between the glycoprofiles of salivary TIMP-1 and plasma TIMP-1.

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The size of the contractile vacuoles increases during cell growth, with the contraction interval strongly depending on the osmotic strength of the medium. Association between obstructive sleep apnea and urinary calculi: a population-based case-control study. Eight patients with fungal meningitis (5 with the coccidioidal type, 2 with cryptococcal, and 1 with histoplasmosis) were treated with intravenous (IV) and intrathecal (IT) miconazole after previous therapy with amphotericin B proved unsuccessful. Two evolutionarily conserved kinases, the cyclin B (Clb)/cyclin-dependent kinase (Cdk/Cdc28p) and Cdc7p along with its interacting factor Dbf4p, are required late in G1 to initiate DNA replication. Clinical and neuroimaging study of central nervous system in congenital myotonic dystrophy. The detection of bacteria was also weakened after prolonged enrichment cultivation of samples from infected fish. These findings indicate that extracts from rabbit skin inflamed by the vaccinia virus can attenuate neurotoxicity induced by intrathecal injection of bupivacaine in pregnant rats, possibly by inhibiting caspase-9 protein expression and suppressing nerve cell apoptosis. However, local injections of a pancaspase inhibitor (Z-VAD-fmk) did not improve survival, although caspase-3 activity was reduced to a similar degree as by the administration of Z-LEHD-fmk.

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We concluded that functionally intact Rb was required for cell cycle-dependent downregulation of telomerase activity in SCC lines. The Day Care Surgical Unit at the Aga Khan University Hospital, Karachi. Excess water-soluble vitamins are thought to be eliminated in the urine. The synovitis was evaluated clinically and ultrasonographically in 24 knee joints prior to the AS synovectomy and 7 days, and 3, 6 and 12 months after it. Separation of ionic currents responsible for action potential generation in isolated neurons of frog spinal ganglia. A coordinating role of all national and supranational bodies present in the area is desirable in the near future. Our study provides several clinically interesting findings and further supports the hypothesis of chromosome 1p and 19q involvement in the oligodendroglial cancerogenesis.

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Re: Prophylactic analgesia before percutaneous liver biopsy: a clinical comparative study. The GaN film is released and transferred onto arbitrary substrates. In diabetic patients organ perfusion is reduced and this is linked to atherosclerosis, and as a result complications occur. In this study, 25 BTV12 NS1-reactive monoclonal antibodies (MAbs) and polyclonal antisera (polyclonal antibodies, PAbs) were generated and analyzed. High-speed focal modulation microscopy using acousto-optical modulators. The Rey Auditory-Verbal Learning Test, which is used to evaluate learning and memory, is a widely recognized tool in the general literature on neuropsychology. Based on our review of the literature, there are several small-scale studies of these two therapies that have revealed favorable outcomes, but with complications of urinary incontinence and impotence. In this respect, a total of 5580 drugs and drug-like molecules was collected from 256 different articles published between 1992 and 2010. Countries categorised as having comprehensive public insurance coverage showed a tendency towards less insurance variation within their populations than did countries categorised as not having comprehensive public coverage. This study found no increased frequency of allergy in general in women who have had pregnancy rhinitis.

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Aflatoxin M1 absorption and cytotoxicity on human intestinal in vitro model. A difficult to diagnose subgroup of CMS is characterised by proximal muscle weakness and fatigue while ocular and facial involvement is only minimal. This paper describes the CEM and reviews the research so-far in relation to the model. The anatomic, neural and endocrine systems that support these symptomatic functions and dysfunctions span the range from the urogenital smooth muscle to the hypothalamus, the bladder sensory output to the micturition centre and growth factors to androgens. The objective of this formative research was to explore the acceptability and feasibility of changing housekeeping behaviors as a low-cost approach that may reduce childhood lead exposure in Johannesburg, South Africa. In those species with a dorsal sac, its close association with the pineal-end-vesicle suggests a functional relationship between the two structures. Batimastat had a dose-related effect on embryo growth and viability following 48 h in culture, with significant inhibition at 1.0 microM concentration. Profilaggrin is proteolytically processed into individual domains during the terminal differentiation.

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Visual analysis showed a strong downward trend after music listening for teeth-grinding, and no change over all conditions for mouth-scratching. Interestingly, the preliminary sequence comparison of the amplicons for four enterococcal species demonstrated that there were some sequence variations which may be used to generate species-specific internal probes. Smears of approximately 500 base pairs were observed in the 1-year-old and 10-year-old samples. The CF knowledge scale has potential applications as a clinical teaching tool with patients and health-care providers and could be used as an outcome measure in CF educational intervention studies aimed at optimizing CF treatment knowledge, adherence and quality of life among CF patients. Linking the subcultures of physics: virtual empiricism and the bonding role of trust. A proposed recommendation for a National Health Services System. A synergistic effect to increase protein stability between accumulation of osmolytes and protein engineering strategies seems to have operated during evolution. The incidence of major salivary gland cancers in Spain was low and a decreasing trend was identified between 1991 and 2001. Preoperative infliximab is not associated with an increased risk of short-term postoperative complications after restorative proctocolectomy and ileal pouch-anal anastomosis.

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Comparison of influenza outbreaks in the Republic of Kazakhstan and Russia induced by 2009 yearly new variant of A(H1N1) influenza virus. Actions to promote cycling in cities should go together with improving road safety. The E23K gene polymorphism of Kir6.2 gene was analyzed by PCR-restriction site polymorphism (PCR-RSP) methods in 101 controls and 119 CHD patients. In this review the authors focus on biological applications and technologies that utilise two types of related plasmonic phenomonae: localised surface plasmon resonance (LSPR) spectroscopy and surface-enhanced Raman spectroscopy (SERS). Several regulators (mammalian target of rapamycin, serum response factor, atrogin-1, myostatin, etc.) seem to modulate protein synthesis and degradation or transcription of muscle-specific genes during both sarcopenia and muscular dystrophy. We report here the identification of a W-linked marker in the ostrich (Struthio camelus) which allows gender diagnosis in chicks or juvenile birds. The rate of grading concordance and the effect of different variables on the concordance rate was determined. The impact of osteoblastic differentiation on osteosarcomagenesis in the mouse. The experiments were designed with a 2(5-1) reduced factorial design and analyzed in terms of multivariate regression models.

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Imaging patterns of hepatic steatosis on multidetector CT: pearls and pitfalls. Direction and magnitude of nicotine effects on the fMRI BOLD response are related to nicotine effects on behavioral performance. Mutual cooperation, collaboration and by integrating TH into primary oral health care services needs to be increased. Women who reported recent vibrator use with other women had higher mean sexual functioning scores than women who reported no vibrator use or vibrator use only during masturbation. Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B. Conclusions and future directions for periodic reporting on the use of selected clinical preventive services to improve the health of infants, children, and adolescents--United States. These results report novel TUDCA anti-inflammatory actions, with potential therapeutic implications for neurodegenerative diseases, including retinitis pigmentosa. The plaster cast immobilization has a greater effect on the homoeostasis of the nucleic acids of the tonic muscles than in the case of the tetanic muscles.

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