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Zofran (Ondansetron)

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Zofran is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. Zofran works by blocking one of the body's natural substances (serotonin) that causes vomiting.

Other names for this medication:
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Also known as: Ondansetron


Ondansetron is used to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy) or radiation therapy. It is also used to prevent nausea and vomiting that may occur after surgery. Ondansetron works in the stomach to block the signals to the brain that cause nausea and vomiting.

This medicine is available only with your doctor's prescription.


Take each dose with a full glass of water. Take Generic Zofran with food or an antacid to lessen stomach discomfort. If you want to achieve most effective results do not stop taking Generic Zofran suddenly.


Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.


Keep the medicine in the foil pouch until you are ready to use it. Store at room temperature, away from heat and direct light. Do not freeze.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep the unused soluble film in the foil pouch until you ready to use it.

Detailed Zofran dosage information

Side effects

The most common side effects associated with Zofran are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Zofran ODT if:

you are also using apomorphine (Apokyn); or you are allergic to Zofran ODT or similar medicines (dolasetron, granisetron, palonosetron).

To make sure Zofran ODT is safe for you, tell your doctor if you have:

liver disease; an electrolyte imbalance (such as low levels of potassium or magnesium in your blood); congestive heart failure, slow heartbeats; a personal or family history of long QT syndrome; or a blockage in your digestive tract (stomach or intestines).

Zofran ODT is not expected to harm an unborn baby. Tell your doctor if you are pregnant.

It is not known whether ondansetron passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Zofran ODT is not approved for use by anyone younger than 4 years old.

Zofran ODTly disintegrating tablets may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).

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Spontaneous increase of DNA turnover in murine systemic lupus erythematosus. The expression levels of interferon beta 1 (Ifnb1) were increased significantly in Isg15, Socs1 or Socs3 siRNA treated cells. Anticoccidial activity of salinomycin in floor-pen experiments with broilers. However, in developing and in implementing such a system, several country-specific contextual and technical factors would need to be balanced. To determine normal concentrations of 17alpha-hydroxyprogesterone (17OHP) for premature infants. A focused, agent specific approach, as well as a series of generic measures for the prevention of poisoning to children under 5 is advocated. CIITA promoter III is constitutively active in mature B-lymphocytes. Bleeding could not be controlled by beta-blockers, and endoscopic therapy was not considered given the extension of the antral vascular lesions.

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Endothelial L-selectin ligands are likely to recruit lymphocytes into rejecting human heart transplants. Determination of the active principle of a plictran preparation and its metabolites in environmental objects. The management plan, which was evidence based and prospectively decided, was to extract the symptomatic ITMs and to leave the asymptomatic ones untreated, regardless of their impacted position. Treated wastewater irrigation: uptake of pharmaceutical and personal care products by common vegetables under field conditions. These patterns held regardless of the level of uncertainty in hospital environments.

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