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Zanaflex (Tizanidine)

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Zanaflex is a muscle relaxer. It provides relief from the discomfort associated with acute, painful musculoskeletal conditions such as rigidity, tension, stiffness, and muscle spasms.

Other names for this medication:

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Also known as: Tizanidine


Tizanidine is used to help relax certain muscles in your body. It relieves spasms, cramping, and tightness of the muscles caused by medical problems, such as multiple sclerosis or certain injuries to the spine. Tizanidine does not cure these problems, but it may allow other treatment, such as physical therapy, to be more helpful in improving your condition.

Tizanidine acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of the medicine's side effects.

This medicine is available only with your doctor's prescription.


Usual Adult Dose for Muscle Spasm:

-Initial dose: 2 mg orally every 6 to 8 hours as needed -The dose of Zanaflex can be increased by your doctor if needed -The medication effects peak in about 1 to 2 hours and last for 3 to 6 hours -Do not take more than 16mg of Zanaflex at one time. Do not take more than 36mg in 24 hours.

Comments: -The capsules and tablets are absorbed differently by the body. Do not switch from one to the other without talking to your doctor. -Zanaflex should be taken with food every time or without food every time. Do not switch back and forth.

Detailed Zanaflex dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include weakness, drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, or fainting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Zanaflex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of tizanidine in the pediatric population. Safety and efficacy have not been established.

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