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Viagra

Sildenafil is a vasoactive agent used to treat erectile dysfunction and reduce symptoms in patients with pulmonary arterial hypertension (PAH). Sildenafil elevates levels of the second messenger, cGMP, by inhibiting its breakdown via phosphodiesterase type 5 (PDE5). PDE5 is found in particularly high concentrations in the corpus cavernosum, erectile tissue of the penis. It is also found in the retina and vascular endothelium. Increased cGMP results in vasodilation which facilitates generation and maintenance of an erection. The vasodilatory effects of sildenafil also help reduce symptoms of PAH.

Other names for this medication:
Caverta, Intagra, Kamagra, Penegra, Revatio, Silagra, Sildenafil, Sildenafila, Sildenafilo, Sildenafilum, Sildigra, Suhagra, Veega, Zenegra

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Also known as: Sildenafil

Description

Viagra is approved to treat erectile dysfunction (ED) in men. With ED, you have trouble getting and keeping an erection that’s firm enough to allow you to have sex.

What causes an erection?

When you’re sexually aroused, either through sexual thoughts or touch, your brain sends messages to your penis. These messages cause certain chemicals to be released in your penis.

One of these chemicals, called cyclic GMP, relaxes and widens certain blood vessels in your penis. Cyclic GMP also relaxes the muscles around the erectile tissue in your penis that’s called the corpus cavernosum. These actions allow blood to flow into the corpus cavernosum, which causes your penis to get hard and become erect.

What happens with ED?

ED can occur if you have certain problems that affect your body’s ability to have an erection. The condition can result from problems with messages being sent from your brain. ED can also result from problems with blood flow into your penis.

What does Viagra do for ED?

Viagra works to treat ED by helping you have and maintain an erection. The drug does this by improving blood flow into your penis when you’re sexually aroused.

Viagra is a type of drug called a phosphodiesterase type 5 (PDE5) inhibitor. It works by inhibiting (blocking) the action of an enzyme called PDE5. (An enzyme is a protein that helps chemical reactions to happen inside your body.)

Normally, an erection goes away when PDE5 breaks down the cyclic GMP in your penis. But Viagra blocks the action of PDE5, so it allows cyclic GMP to keep working for a longer period of time than usual. This action improves blood flow to your penis and helps you to have and keep an erection.

Does Viagra increase a man’s sex drive?

No, Viagra doesn’t directly increase your sex drive. And it doesn’t make you sexually aroused. However, some men find that if Viagra works to treat their erectile problem, it also increases their sexual confidence. And this may lead to an increased sex drive.

How can I tell if Viagra’s not working?

Viagra may not work for everyone, and it may not work every time you take it.

If you’re sexually aroused, Viagra should work to help you have or keep an erection within 30 minutes to 2 hours. But if you don’t get an erection within 4 hours after taking a dose, Viagra didn’t work for you this time.

If the drug doesn’t work for you, you shouldn’t take another dose until at least 24 hours later. And talk with your doctor if you feel Viagra isn’t helping to treat your ED. They may recommend that you try a different medication for your ED.

How can I get Viagra to work?

It’s important to remember that Viagra only works if you’re already sexually aroused. Arousal may involve having sexual thoughts, looking at sexual images, masturbating, or engaging in foreplay.

But if you feel anxious, nervous, depressed, or stressed, your body may not respond well to sexual stimulation. If this is the case, try to relax, make yourself comfortable, and take your time. In addition, it’s best to avoid drinking a lot of alcohol. This is because consuming large amounts of alcohol can make it more difficult for you to get an erection.

If you’re having trouble getting an erection, even while using Viagra, talk with your doctor.

Is Viagra a blood thinner?

No, Viagra isn’t a blood thinner. Instead, it belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. (A class of drugs describes a group of medications that work in a similar way.) Viagra works by inhibiting (blocking) the action of a certain enzyme in your body.

Since Viagra has been released onto the market, there have been a few reports of bleeding in people who’ve taken the drug. However, there’s no evidence that Viagra caused these bleeding problems.

It’s not known if Viagra is safe for use by people with a bleeding problem. If you have any bleeding problems, talk with your doctor about whether Viagra is safe for you.

Dosage

The Viagra dosage your doctor prescribes will depend on several factors. These include:

  • your age
  • whether you have liver or kidney problems
  • other medical conditions you may have
  • other medications you may be taking
The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Drug forms and strengths

Viagra comes as tablets that are taken by mouth. It’s available in three strengths: 25 mg, 50 mg, and 100 mg.

Dosage for ED

The typical dose of Viagra for erectile dysfunction (ED) is 50 mg. You can take this dose 30 minutes to 4 hours before you plan to have sexual activity. But for most people, it’s recommended that you take your dose about an hour before having sex. Don’t take Viagra more than once a day.

Your doctor may prescribe a different dosage of Viagra for you depending on several factors. These factors may include whether you have liver or kidney problems, or if you’re taking certain other medications. If any of these factors apply to you, your starting dose might be 25 mg, which is lower than the typical recommended dose.

If you have questions about the Viagra dosage that’s right for you, talk with your doctor.

And keep in mind that if Viagra isn’t working for you, your doctor may increase your dose of the drug. But the maximum dose of Viagra is 100 mg.

Dosage questions

Below, we answer some common questions related to Viagra’s dosage.

Is Viagra’s dosage based on age or weight?

Your dosage of Viagra won’t be based on your weight, but it may be based on your age.

For example, people ages 65 years and older tend to get higher levels of Viagra in their blood after taking a dose. So, if you’re over 65 years of age, your doctor will usually recommend a starting dose of Viagra for you that’s lower than the typical starting dose. For example, they may recommend that you take 25 mg of the drug rather than 50 mg.

Can I take Viagra just for fun, even if I don’t have ED? If so, how much is safe to take?

No, you shouldn’t take Viagra if you don’t have ED. Viagra is a prescription medication that can have serious side effects. And it’s approved only to treat ED, not to be used recreationally.

You should only take Viagra if it’s been prescribed to you by a doctor who knows your medical history.

Will I need to use this drug long term?

Maybe. If you and your doctor determine that Viagra is safe and effective for you, you can likely take it for as long as you continue to need it.

Overdose

If you take an overdose of Viagra, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

The most common side effects associated with Viagra are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Below are the cases in which Viagra is contraindicated in men:

Low/high blood pressure - sildenafil should not be used in case of severe cases of hypotension as well as hypertension. If an individual is taking medicines for hypotension or hypertension, Viagra may interact with the drug and make it ineffective.

In case of recently encountered heart attack or stroke - if an individual has recently encountered a stroke or heart attack, he must not take sildenafil as it can again trigger the condition or even make it worse.

In women, pregnancy and mothers of newborn - the drug should be used for treatment of erectile dysfunction in men. This medicine is contraindicated for use in women and pregnant mothers.

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