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Primozyn (Promethazine)

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Primozyn blocks the action of chemicals in the body that can make you feel or be sick. Primozyn helps you recover more comfortably. It is often used to prevent nausea and vomiting that may be caused due to some medicines or any other medical treatment.

Other names for this medication:
Abrozin, Admol, Avomine, Biodol, Calmkid, Ceedokid, Emispan, Enimol, Ibuprom, Kidkof, Lagesic, Lincotuss, Metacet, Parapro, Petrox, Phenomet, Pizol, Procalm, Progene, Promacot, Promethazine, Promethegan, Promyoz, Propar, Prosed, Prosip, Prosym, Pyrivin, Symol, Tymol, Vomica, Vomin

Similar Products:
Ticlid, Zebeta, Zyprexa, Diovan, Aldara, Scavista, Renaton, Ranid, Modapro, Indonet, Metazol, Udipan, Ampliar,

Also known as: Promethazine


Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant, and an analgesic, in addition to a medicine for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Also, in general, it is best to buy a product that includes only those medicines you really need. If you have questions about which product to buy, check with your pharmacist.

Since different products contain ingredients that will have different precautions and side effects, it is important that you know the ingredients of the medicine you are taking. The different kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines—Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are:

Bromodiphenhydramine Brompheniramine Carbinoxamine Chlorpheniramine Dexchlorpheniramine Diphenhydramine Doxylamine Phenindamine Pheniramine Phenyltoloxamine Pyrilamine Promethazine Triprolidine

Decongestants—Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in patients who have high blood pressure. These include:

Ephedrine Phenylephrine Pseudoephedrine

Antitussives—Antitussives help relieve coughing and are some contain a narcotic. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if used for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Narcotic antitussives Codeine Dihydrocodeine Hydrocodone Hydromorphone

Non-narcotic antitussives Carbetapentane Caramiphen Dextromethorphan

Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and cold medicines is guaifenesin. Other ingredients added as expectorants (for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide, and sodium citrate) have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics—Analgesics are used in these combination medicines to help relieve the aches and pain that may occur with the common cold. These include:

Acetaminophen Aspirin Other salicylates such as salicylamide and sodium salicylate

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medicines are taken together for a long time. However, taking the recommended amounts of combination medicines that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics—Anticholinergics, such as homatropine may help produce a drying effect in the nose and chest.

These cough and cold combinations are available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .


Take Primozyn exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Primozyn is often taken at bedtime or before meals. For motion sickness, Primozyn is usually started within 1 hour before traveling. When used for surgery, Primozyn is usually taken the night before the surgery.

How often you take Primozyn and the timing of your dose will depend on the condition being treated.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

If a child is using this medicine, tell your doctor if the child has any changes in weight. Primozyn doses are based on weight in children, and any changes may affect your child's dose.

Call your doctor if your symptoms do not improve, or if they get worse while using Primozyn.

This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using Primozyn.

Store Primozyn at room temperature away from moisture, heat, and light.

Detailed Primozyn dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include overactive reflexes, loss of coordination, severe drowsiness or weakness, fainting, dilated pupils, weak or shallow breathing, or seizure (convulsions).


Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Keep the liquid form of this medicine from freezing. Do not refrigerate the syrup.

Detailed Codeine/promethazine dosage information

Side effects

The most common side effects associated with Primozyn are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Extending the pathway analysis framework with a test for transcriptional variance implicates novel pathway modulation during myogenic differentiation. On western blots, the antiserum labeled two constitutively expressed proteins with distinct expression patterns. Significantly higher mean pH values and NOC concentrations were found in partial gastrectomies compared to normal controls. Piperine was administered to mature male albino rats at doses of 5 and 10 mg/kg body weight, p.o., respectively, for 30 days. These results confirm that, in response to Shigella infection, the normal expression pattern of MUC-2 and MUC-5AC is altered. Binding of iron, zinc, and lead ions from aqueous solution by shea butter (Butyrospermun parkii) seed husks. We assembled interaction webs of protist consumers and turbellarian predators with eight different combinations of prey, predators and nonprey species, and recorded abundances for over 130 prey generations. 5-HT is also involved in the control of neurotrophic processes during pre- and postnatal development of neural circuits. Fine-needle aspiration cytology of suture granulomas of the breast: a potential pitfall in the cytologic diagnosis of recurrent breast cancer.

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Distribution of aflatoxigenic Aspergillus section Flavi in commercial poultry feed in Nigeria. Purification and characterization of a dicyclohexylcarbodiimide-sensitive adenosine triphosphatase complex from membranes of Escherichia coli. Physical Activity and Falls in Older Men: The Critical Role of Mobility Limitations. The questionnaire was constructed as follows: a review of literature, collection of symptoms as well as social and emotional consequences by a panel of ENT specialists and general practitioners, interviews with patients experiencing ARS, and a pre-test with another patient group. A motrin gel strong healthy worker effect was observed for the cohort, which diminished with longer time since first employment for fire fighters with shorter duration of employment, as expected. Chondroitin sulfate or heparin, added to the culture media of these cells, stimulates the production of chondroitin sulfate proteoglycan over the entire period of culture with a maximum effect during the log phase of growth. Complex regional pain syndrome (CRPS) is a chronic pain disorder characterized by severe pain and vasomotor and pseudomotor changes. Ten structures were generated using distance geometry methods, followed by dynamic simulated annealing calculations. PCC 6803: their role in binding or transfer of newly synthesized chlorophyll. Evaluation of therapeutic modalities in patients with life threatening arrhythmias.

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Isolation and molecular biological investigations of avian poxviruses from chickens, a turkey, and a pigeon in Croatia. JEV or JEV-induced macrophage derived factor (MDF) induces increase in intracellular oxidative signals with generation of superoxide anion (O2-), via activation of cytosolic NADPH and subsequent formation of hydrogen peroxide, with maximum activity on day 7 post infection. We developed a novel poly(vinylidene difluoride) membrane for the identification of labeled peptides in a simple dot blot assay. The recent development of superconducting magnets has resulted in a huge increase in human exposure to very large static magnetic fields of up to several teslas (T). For vegetatively propagated crops, sanitation by roguing has a low risk of failure owing to its combination of selecting for low virus titre strains as well as increasing healthy crop density. Mice lacking tartrate-resistant acid phosphatase (Acp 5) have disrupted endochondral ossification and mild osteopetrosis. Informed consent was reportedly compromised due to language barriers by 29 per cent of respondents. Patients were divided into three groups according to the meniscus type: torn discoid lateral meniscus (Group A), torn nondiscoid lateral meniscus (Group B), and nondiscoid lateral meniscus without a tear (Group C).

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