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Prandin (Repaglinide)
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Prandin

Prandin can cause low blood sugar (hypoglycemia). Low blood sugar also can happen if you use Prandin with another diabetes medication, delay or miss a meal or snack, exercise more than usual, drink alcohol, or cannot eat because of nausea or vomiting.

Other names for this medication:
Eurepa, Novonorm, Rapilin, Regan, Reglide, Repaglinide, Repamon, Repide

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Also known as: Repaglinide

Description

Prandin (repaglinide) is an oral diabetes medicine that helps control blood sugar levels by causing the pancreas to produce insulin.

Prandin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Prandin is not for treating type 1 diabetes.

Dosage

Usual Adult Dose for Diabetes Type 2:

Individualize therapy: Dose preprandially 2, 3, or 4 times a day -For patients not previously treated with antidiabetic agents or whose glycosylated hemoglobin (HbA1c) is less than 8%: Initial dose: 0.5 mg orally with each meal -For patients previously treated with antidiabetic agents or whose HbA1c is 8% or higher: Initial dose: 1 or 2 mg orally with each meal Dose Adjustments: Based upon blood glucose response, double the preprandial dose up to a maximum meal time dose of 4 mg until satisfactory glycemic response is achieved; allow at least 1 week to assess response after each dose adjustment. Recommended Dose Range: 0.5 to 4 mg orally with each meal Maximum Daily Dose: 16 mg per day Comments: -Fasting blood glucose concentrations are generally used to adjust doses, however, postprandial glucose levels may be used in patients whose pre-meal blood glucose levels are satisfactory but whose overall glycemic control (HbA1c) is inadequate. -When hypoglycemia occurs in patients taking this drug in combination with a thiazolidinedione or metformin, the dose of this drug should be reduced. Use: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Detailed Prandin dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A repaglinide overdose can cause life-threatening hypoglycemia.

Symptoms of severe hypoglycemia include extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Prandin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Prandin if you are allergic to Prandin components. Be careful with Prandin if you're pregnant or you plan to have a baby, or you are a nursing mother. Prandin is not taken to treat type 1 diabetes. You can normally take insulin while using Prandin. Do not use Prandin in case of having type 1 diabetes, diabetic ketoacidosis, liver disease, poor adrenal, pituitary function. Try to be careful with Prandin in case of using such medication as sulfa drugs (Gantanol); isoniazid; niacin (Nicobid); water pills (thiazide diuretics HydroDIURIL, Dyazide); beta blockers (blood pressure medications as Tenormin, Inderal); barbiturates (sedatives as Nembutal, Seconal); calcium channel blockers (blood pressure medications as Procardia, Cardizem); Rifampin (Rimactane, Rifadin); oral contraceptives; ketoconazole (Nizoral); chloramphenicol (Chloromycetin); nonsteroidal anti-inflammatory drugs (Voltaren, Motrin, Advil, Naprosyn); blood thinners (Miradon, Dicumarol); steroids as prednisone; furosemide as Lasix; clarithromycin as Biaxin; thyroid medications as Synthroid; phenytoin as Dilantin; Probenecid (ColBENEMID, Benemid); estrogens (Premarin); aspirin; erythromycin (PCE, Eryc, Ery-Tab); MAO inhibitors (antidepressants Parnate, Marplan, Nardil); glucose lowering agents (Micronase, Glucotrol); carbamazepine (Tegretol); major tranquilizers (Stelazine, Mellaril). You can use Prandin in case exercise and diet does not help. Prandin can be taken together with anti-diabetic medication as Glucophage. Try to avoid unhealthy food. Avoid consuming alcohol. Do not stop taking Prandin suddenly.

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