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Lamictal (Lamotrigine)
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Lamictal

Lamictal is used alone or with other medications to prevent and control seizures. It may also be used to help prevent the extreme mood swings of bipolar disorder in adults. Lamictal was first marketed in the United Kingdom in 1991, and approved for use in the United States in 1994.

Other names for this medication:
Epitic, Eptic, Lamepil, Lamepri, Lametec, Lamidus, Lamitor, Lamogin, Lamonex, Lamorig, Lamosyn, Lamotrigine, Laogine, Lemit, Lemogen, Lemoring, Lyzin

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Also known as: Lamotrigine

Description

Lamictal ODT is an anti-epileptic medication, also called an anticonvulsant.

Lamictal ODT is used alone or with other medications to treat epileptic seizures in adults and children. This medicine is also used to delay mood episodes in adults with bipolar disorder (manic depression).

Immediate-release Lamictal ODT can be used in children as young as 2 years old when it is given as part of a combination of seizure medications. However, this form should not be used as a single medication in a child or teenager who is younger than 16 years old.

Extended-release Lamictal ODT is for use only in adults and children who are at least 13 years old.

Dosage

Take Lamictal exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.

Taking too much Lamictal at the start of treatment may increase your risk of a severe life-threatening skin rash.

You may need frequent blood tests to help your doctor make sure you are taking the right dose.

Extended-release and immediate-release Lamictal may be used for different conditions. Always check your refills to make sure you have received the correct size, color, and shape of tablet. Avoid medication errors by using only the form and strength your doctor prescribes.

If you switch to Lamictal from another seizure medicine, carefully follow your doctor's instructions about the timing and dosage of your medicine.

Lamictal tablets should be swallowed whole. Do not crush, chew, or break it.

Lamictal chewable dispersible tablets may be swallowed whole, chewed, or mixed with water or diluted fruit juice.

Read and carefully follow any Instructions for Use provided with the orally disintegrating or dispersible tablets. Ask your doctor or pharmacist if you do not understand these instructions.

Do not stop using this medicine suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor's instructions about tapering your dose.

In case of emergency, wear or carry medical identification to let others know you use seizure medication.

Lamotrigine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use lamotrigine.

Store at room temperature away from light and moisture.

Detailed Lamictal dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include blurred vision, problems with coordination, increased seizures, feeling light-headed, or fainting.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

The most common side effects associated with Lamictal are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

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Correct species identification is the basis of ecological studies. During the larval-pupal transition, a switch from gene activation by EcR/Usp to gene repression by E75A is triggered by a decrease in ecdysone concentration and by direct repression of the EcR gene by E75A. Activity-based high-throughput profiling of metalloprotease inhibitors using small molecule microarrays. The modified Gleason system of 2005 recommends incorporating higher grade tertiary patterns on needle biopsy into final Gleason scores to better correlate with radical prostatectomy findings. This trial studied the impact of agitation on the corticoid concentration of eye drop solutions, gels, and suspensions.

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Literary reports of shoulder dystocia indicate that the incidence of shoulder dystocia has increased in the USA about fourfold since the middle of the twentieth century. Histological and ultrastructural analyses revealed progressive myelin vacuolation, in parallel to disease development that includes motor deficits, tremor, and ataxia. The topics discussed are relevant to all mental health practitioners who are interested in clinical telepractice services. The HDL values reported, however, differ greatly from all other published values, and the period of follow-up was less than 5 years. Collagen accumulation and the development of lipid inclusions were less extensive in the presence of progesterone. Late onset congenital central hypoventilation syndrome after exposure to general anesthesia. Levels of the cyclooxygenase 2 (COX2) enzyme are elevated in breast cancer tissue, and most COX2 effects are believed to be mediated through overproduction of prostaglandin E2 (PGE2). A similar degree of confidence is warranted for E-coding at the group level (for example, fall), but not, in general, at higher levels of specificity (for example, type of fall). We found that a deficiency of endogenous CoQ synthesis down-regulates a cluster of genes that are important for growth (i.e., RNA polymerase II, eukaryotic initiation factor) and up-regulates oxidation reactions (i.e., cytochrome P450, superoxide dismutase) and protein interactions (i.e., F-Box proteins). The functional characteristics of SIS, replaced within 6 months by newly formed connective tissue, suggest a lower long-term risk of infection and erosion.

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Analysis of the lipids of seven species of Micromonospora showed the constant presence of five phospholipids and three glycolipids. Introduction: cancer of the head and neck: a challenge and a dilemma. To contribute to the knowledge of the cognitive differences existent between right-handed and left-handed evaluating the cognitive outcome in a group of adults right-handed and another group of left-handed of similar characteristic (age, gender, cultural level) by means of the Wechsler Adult Intelligence Scale (WAIS-III). Oscillometry significantly underestimated systolic and significantly overestimated diastolic blood pressures in each of the 4 weight groups studied. This brief review highlights the functional importance of various potassium channels to the electrophysiology of the heart and presents relevant molecular information about the structures that constitute this important family of integral membrane proteins. Also, the treatment needs on the basis of Community Periodontal Index of Treatment Needs (CPITN), which might be helpful for future planning of dental services. Type 2 diabetes is associated with oxidative DNA damage, and we hypothesized that telomere shortening would characterize type 2 diabetes.

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Macroscopically, the lesion resembled a papillary microcarcinoma. A retrospective study was performed of referrals for suspected glaucoma to an ophthalmology department during a 3 month period. The free energy changes for ethyl isocyanide binding to the two chains are nearly identical, suggesting that the linear and bent geometries are energetically equivalent. The Effect of Different Standing up Frequencies in Sit-to-stand Exercise on Oxygen Uptake. These findings suggest that the electrical conduction rate to the posterosuperior septum area in Brugada syndrome cases is low, and this low activation may be a feature of typical Brugada syndrome. We investigated the impact of dairy food consumption on biomarkers of inflammation in healthy men and women with low-grade systemic inflammation. The advanced hypopharyngeal cancers surgery treatment complications. Comparisons are made based on organizational affiliation and findings indicate agencies that become affiliated with larger and more complex organizations are more frequently proprietary agencies. Positive selection and multiple losses of the LINE-1-derived L1TD1 gene in mammals suggest a dual role in genome defense and pluripotency. The acticin quantitative dependence of integrin-mediated adhesion nucleation on substrate rigidities is systematically explored, which shows a reasonable agreement with existing experimental results.

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Studies on the local immune response of the lactating ewe infected with Ostertagia circumcincta. Primary cutaneous T cell lymphomas (CTCL) represent the most frequently occurring group of extra-nodal T cell lymphomas, originating from skin-homing memory T cells. As a result, she regained substantial muscle strength along with complete normalization of serum muscle enzymes and showed no evidence of recurrence of papillary thyroid cancer or exacerbation of dermatomyositis (DM). A polymerase chain reaction (PCR) based strategy to detect episomal banana streak badnavirus (BSV) in banana and plantain plants that carry integrated BSV sequences was developed. Female patients with poor shoulder function and generalized muscle weakness prior to surgery have a greater likelihood of having a poor clinical result.

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Edwards School of Medicine, Marshall University, in Huntington, West Virginia, USA. Normal lung volumes do not exclude diagnosis of idiopathic pulmonary fibrosis in patients with concomitant emphysema. CsA, and to a lesser degree Tac infusions, in healthy volunteers include increased insulin sensitivity, without any effect on first phase generic albuterol vs ventolin or pulsatile insulin secretion. Therapeutic doses of radiation for paraspinal tumors are often limited by the dose-related tolerance of the spinal cord. Hypertension: adherence to treatment in rural Bangladesh--findings from a population-based study. The analysis utilizes a sample of 654 Indigenous children from four reservations in the Northern Midwest and four Canadian First Nation reserves.

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Pregnancy-associated plasma protein A2 (PAPP-A2, also known as pappalysin-2) is a large metalloproteinase that is known to be required for normal postnatal growth and bone development in mice. Although the therapy schedule did not prolong MST or CNS-TTP, further assessment is warranted. Before the time of hatching, the high columnar epithelium changes to low columnar epithelium again in a distal to proximal direction. We found that the formation of apoptotic bodies during apoptosis induced by rattlesnake venom, which is an unique and specific apoptosis inducer to vascular endothelial cells, was much faster than that induced by deprivation of survival factors (aFGF and serum). Standard dissolution tests were used to observe the sustained release phenomenon of the composite particles. We present the case of a 83-year-old female who developed large mass in the right kidney. They result from integrating expression data from a large number of globally normalized and quality controlled public experiments. Osteoporosis in multiple endocrine neoplasia type 1: severity, clinical significance, relationship to primary hyperparathyroidism, and response to parathyroidectomy. However, other studies have shown that P2X6 can form functional heteromeric receptors with P2X2 and P2X4 subunits. Part 2: Preadmission testing, concurrent review and outpatient surgery.

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Altered HA308-317 peptides with substitutions of TCR-contact residues may inhibit HLA-DR1/4-specific T-cell activation by blocking the antigen-binding site of HLA-DR1/4 molecules. SANADII, a phase IV pragmatic trial, managed by the Clinical Trials Research Centre, Liverpool. These results suggest that the function of the carotid body may be influenced by the proinflammatrory cytokines through their receptors. The experimental results show that the instrument integrated with gas concentration inversion algorithm can be applied to in-situ measurements of trace gases without calibration. Diseases of the epidermis: pityriasis rosea, lichen planus, keratosis pilaris.

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