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Depranil (Imipramine)
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Depranil

Depranil is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and Depranil. While it acts to block both, Depranil displays a much higher affinity for the serotonin reuptake transporter than for the norepinephrine reuptake transporter.

Other names for this medication:
Alzoset, Antidep, Anxitab, Anxofit, Depforte, Depik, Depof, Depranil, Deprid, Depsan, Depsin, Depsodep, Depsol, Depsolam, Depsonil, Diamin, Diazariv, Elamin, Eldep, Elidep, Endopax, Estidep, Finezol, Imidiaz, Imikon, Imilor, Iminza, Imipam, Imipra, Imipramine, Imodep, Impranit, Imprax, Imprim, Karthin, Lastinem, Libomin, Nimipose, Prazep, Talendep, Toframine, Trydep, Ultradep

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Also known as: Imipramine

Description

Imipramine is used to treat depression. It belongs to a group of medicines known as tricyclic antidepressants (TCA). These medicines are thought to work by increasing the activity of a chemical called serotonin in the brain.

Imipramine tablets are also used to treat enuresis (bedwetting) in children.

This medicine is available only with your doctor's prescription.

Dosage

Take Generic Depranil orally. Take Generic Depranil with or without food. For adults The usual starting dose is 75 mg a day. The maximum daily dose is 200 mg. For children Total daily dosages for children should not exceed 2.5 mg for each 2.2 pounds of the child's weight. Doses usually begin at 25 mg per day. This amount should be taken an hour before bedtime. If needed, this dose may be increased after 1 week to 50 mg (ages 6 through 11) or 75 mg (ages 12 and up), taken in one dose at bedtime or divided into 2 doses, 1 taken at mid-afternoon and 1 at bedtime. Aged people The usual dosage should start with 25 to 50 mg per day. The dose may be increased as necessary, but effective dosages usually do not exceed 100 mg a day. If you want to achieve most effective results do not stop taking Generic Depranil suddenly.

Overdose

If you overdose Generic Depranil and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Depranil overdosage: agitation, bluish skin, convulsions, difficulty breathing, dilated pupils, drowsiness, heart failure, high fever, involuntary writhing or jerky movements, irregular or rapid heartbeat, lack of coordination, low blood pressure, overactive reflexes, restlessness, rigid muscles, shock, stupor, sweating, vomiting.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Depranil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Depranil if you are allergic to it, or if:

you recently had a heart attack; or you are allergic to other antidepressants (amitriptyline, amoxapine, clomipramine, desipramine, doxepin, nortriptyline, protriptyline, or trDepranil).

Do not use Depranil if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

Tell your doctor if you have ever had:

heart disease, stroke, or seizures; bipolar disorder (manic-depression), schizophrenia or other mental illness; kidney or liver disease; overactive thyroid; narrow-angle glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

It is not known whether Depranil will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breastfeed while using Depranil.

Do not give this medicine to a child without medical advice. Depranil is not approved to treat depression in anyone younger than 18 years old. This medicine should not be used to treat bed-wetting in a child younger than 6 years old.

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Probable causes of failure in the treatment of isthmico-cervical incompetence. Prenatal genetic diagnosis of severe perinatal (lethal) hypophosphatasia. In situ hybridization documents that in the adult rabbit the transcript accumulates in neurons and is localized in myocytes of the sino-atrial and atrio-ventricular nodes and of the atrio-ventricular bundle and bundle branches, but not in working atrial and ventricular myocytes. Several techniques were used to assess the different stages of deglutition: physical examination during swallowing, videofluoroscopy, pharyngoesophageal manometry, videofibroscopy of the pharynx during swallowing. We also aimed to evaluate the validity of the prognostic scores in the Tomita and Tokuhashi systems and discuss several aspects to improve the predictive accuracy of these systems. Initial clarithromycin monotherapy for Mycobacterium avium-intracellulare complex lung disease. Although certain retardation became apparent in both cases, they are showing satisfactory development in the long-term follow up. Moreover, it is essential to define the goal of HCE and to adapt the experimental conditions to obtain the required cell populations. With conservative management, her symptoms resolved with interval resumption of the air collection evidenced on interval CT. The combined sample included 17,321 interviews with knowledgeable adults about children aged 4-17 years.

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A heavy-drinking-day item is useful for detecting hazardous drinking patterns, and the RAPS is useful for differentiating more problematic drinkers who may benefit from referral from those more likely to respond to a brief intervention. Shortage of skilled birth attendants (SBA) is one of the determinants of maternal mortality in India. The novel epialleles identified in progeny plants regenerated from tissue culture showed partial to complete loss of p1 function indicated by pink or colorless cob glumes. Polymorph counts were maximal by 24 to 48 h, decreasing thereafter. Evidence for a mechanism of initiation of viral persistence in which the cell, and not the virus, plays a critical role has been obtained using the important animal pathogen foot-and-mouth disease virus (FMDV). The study included 40 ears from 32 patients with varying symptoms (e.g., with and without conductive hearing loss, vestibular symptoms, and abnormal auditory sensations). The results of the BPI and EQ-5D assessments indicate that pain relief is associated with improvement of functioning and enhancement of QoL. c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points.

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Phasic measurement of LA function using feature-tracking cardiac magnetic resonance may add important information about the physiological importance of LA fibrosis. Primary terminal end buds have an oblong shape, with long collagen I fibers close to the neck of the terminal end bud and radiating upwards in the direction of growth. Each of the staff members were put into one of six multi-professional teams. Contingency management for treatment of substance use disorders: a meta-analysis. These results suggest that the K92 PST forms both alpha2,8 and alpha2,9 linkages in a successive and nonprocessive fashion. Event-related potential waveforms were normal in the ADHD children with reference to early processing stages, i.e., contingent negative variation, P1-N1 laterality, and processing negativities, suggesting that ADHD children did not differ in their level of preparedness or their ability to mobilize resources for target identification and how long does one dose of klonopin stay in your system categorization. Pelvic floor muscle hypertonicity was implicated in the mid-1990s as a trigger of major chronic vulvar pain. People with vision loss due to three different age-related eye diseases had lower cognitive scores.

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