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Depranil (Imipramine)

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Depranil is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and Depranil. While it acts to block both, Depranil displays a much higher affinity for the serotonin reuptake transporter than for the norepinephrine reuptake transporter.

Other names for this medication:
Alzoset, Antidep, Anxitab, Anxofit, Depforte, Depik, Depof, Depranil, Deprid, Depsan, Depsin, Depsodep, Depsol, Depsolam, Depsonil, Diamin, Diazariv, Elamin, Eldep, Elidep, Endopax, Estidep, Finezol, Imidiaz, Imikon, Imilor, Iminza, Imipam, Imipra, Imipramine, Imodep, Impranit, Imprax, Imprim, Karthin, Lastinem, Libomin, Nimipose, Prazep, Talendep, Toframine, Trydep, Ultradep

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Also known as: Imipramine


Imipramine is used to treat depression. It belongs to a group of medicines known as tricyclic antidepressants (TCA). These medicines are thought to work by increasing the activity of a chemical called serotonin in the brain.

Imipramine tablets are also used to treat enuresis (bedwetting) in children.

This medicine is available only with your doctor's prescription.


Take Generic Depranil orally. Take Generic Depranil with or without food. For adults The usual starting dose is 75 mg a day. The maximum daily dose is 200 mg. For children Total daily dosages for children should not exceed 2.5 mg for each 2.2 pounds of the child's weight. Doses usually begin at 25 mg per day. This amount should be taken an hour before bedtime. If needed, this dose may be increased after 1 week to 50 mg (ages 6 through 11) or 75 mg (ages 12 and up), taken in one dose at bedtime or divided into 2 doses, 1 taken at mid-afternoon and 1 at bedtime. Aged people The usual dosage should start with 25 to 50 mg per day. The dose may be increased as necessary, but effective dosages usually do not exceed 100 mg a day. If you want to achieve most effective results do not stop taking Generic Depranil suddenly.


If you overdose Generic Depranil and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Depranil overdosage: agitation, bluish skin, convulsions, difficulty breathing, dilated pupils, drowsiness, heart failure, high fever, involuntary writhing or jerky movements, irregular or rapid heartbeat, lack of coordination, low blood pressure, overactive reflexes, restlessness, rigid muscles, shock, stupor, sweating, vomiting.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Depranil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Depranil if you are allergic to it, or if:

you recently had a heart attack; or you are allergic to other antidepressants (amitriptyline, amoxapine, clomipramine, desipramine, doxepin, nortriptyline, protriptyline, or trDepranil).

Do not use Depranil if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

Tell your doctor if you have ever had:

heart disease, stroke, or seizures; bipolar disorder (manic-depression), schizophrenia or other mental illness; kidney or liver disease; overactive thyroid; narrow-angle glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

It is not known whether Depranil will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breastfeed while using Depranil.

Do not give this medicine to a child without medical advice. Depranil is not approved to treat depression in anyone younger than 18 years old. This medicine should not be used to treat bed-wetting in a child younger than 6 years old.

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Monitors of depth of anesthesia, ultra-short-acting agents, and combined techniques have minimized minor complications such as nausea and vomiting, and have improved the speed with which these patients recover from anesthesia. Some regularities of the regeneration of the musculature of internal organs. In this review, we will use several exemplary disorders involving each of the 3 types of blood cells to explore the effect of perinatal insults on subsequent development of the affected cell line. In this method, a suspension droplet containing colloidal particles was first spread onto a glass substrate placed in an ethanol vapor environment, and then the droplet was extracted from its center. Autologous transplantation of fascia into the vocal fold for sulcus vocalis. Mechanically assisted walking with body weight support is more effective than overground walking at increasing independent walking in non-ambulatory patients early after stroke. Avian eggs contain maternally derived hormones, including testosterone and progesterone. Reduced dosage of pos-1 suppresses Mex mutants and reveals complex interactions among CCCH zinc-finger proteins during Caenorhabditis elegans embryogenesis.

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Research related to newer OC formulations containing 35 micrograms or less of ethinyl estradiol suggests that the risk of a negative cardiovascular effect is substantially reduced. Metal-etching-free direct delamination and transfer of single-layer graphene with a high degree of freedom. The vascular lesions are characterized by myointimal proliferation and perivascular mononuclear inflammatory infiltrates. Here, we investigate how these properties emerged during evolution. The occurrence of three canals with three separate foramina in mandibular second premolars is very rare. The effect of luteal phase progesterone supplementation on natural frozen-thawed embryo transfer cycles.

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