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Catapres (Clonidine)

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Catapres is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors.2 This activity is useful for the treatment of hypertension, severe pain, and ADHD. Catapres was granted FDA approval on 3 September 1974.

Other names for this medication:
Arkamin, Clodict, Clonidine, Jenloga

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Also known as: Clonidine


Catapres (clonidine) lowers blood pressure by decreasing the levels of certain chemicals in your blood. This allows your blood vessels to relax and your heart to beat more slowly and easily.

Catapres is used to treat hypertension (high blood pressure). It is sometimes given with other medications.

Catapres is also available as a transdermal patch worn on the skin. Do not use two forms of this medicine at the same time.

The Kapvay brand of clonidine is used to treat attention deficit hyperactivity disorder (ADHD). The Duraclon brand of clonidine is an intravenous (IV) form of clonidine used to treat severe pain in cancer patients.


Usual Adult Dose for Hypertension:

Oral: -Initial dose: 0.1 mg orally 2 times a day (morning and bedtime) -Titration: Increments of 0.1 mg orally per day may be made at weekly intervals to desired response -Maintenance dose: 0.2 to 0.6 mg orally per day in divided doses -Maximum dose: 2.4 mg orally per day in divided doses Comments: -Taking the larger portion of the oral daily dose at bedtime may minimize transient adjustment effects of dry mouth and drowsiness Transdermal patches: -Initial dose: 0.1 mg/24 hr patch applied every 7 days -Maintenance dose: If, after 1 to 2 weeks the desired reduction in blood pressure is not achieved, increase the dosage by adding another 0.1 mg/24 hr patch or changing to a larger system -Maximum dose: Doses above two 0.3 mg/24 hr patches applied every 7 days is usually not associated with additional efficacy Comments: -The transdermal patch should be applied to a hairless area of intact skin on the upper outer arm or chest. -Each new patch should be applied on a different skin site from the previous location. -If the patch loosens during 7-day wearing, the adhesive cover should be applied directly over the system to ensure good adhesion. -There have been rare reports of the need for patch changes prior to 7 days to maintain blood pressure control. -When substituting patches for the oral formulation or for other antihypertensive drugs, physicians should be aware that the antihypertensive effect of the patches may not commence until 2 to 3 days after initial application; therefore, gradual reduction of prior drug dosage is advised. Some or all previous antihypertensive treatment may have to be continued, particularly in patients with more severe forms of hypertension. Use: For hypertension, alone or in combination with other antihypertensive agents

Detailed Catapres dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include feeling cold, irritable, weak, drowsy, or light-headed, or having weak reflexes, pinpoint pupils, slow heartbeats, shallow breathing, or a seizure.


Store the patches at room temperature in a closed container, away from heat, moisture, and direct light.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

After removing a used patch, fold the patch in half with the sticky sides together. Make sure to dispose of it out of the reach of children and pets.

Detailed Catapres-TTS dosage information

Side effects

The most common side effects associated with Catapres are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


No information is available on the relationship of age to the effects of clonidine transdermal in geriatric patients. However, elderly patients are more likely to have age-related heart or kidney problems, which may require caution and an adjustment in the dose for patients receiving clonidine transdermal.

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Ghrelin (Gh), a small peptide, which was originally discovered as a gastrointestinal (GI) tropic hormone, has shown to have a presence and function within multiple tissue systems. We demonstrate use of the PCR assay to detect Alternaria DNA in experimentally infested and commercially obtained tomato sauce and tomato powder. In this investigation, we estimated its kinetic parameters at various volumetric ratios of the hydrogen peroxide to hydrochloric acid. Glycans are important contributors to the development and function of the nervous system with enormous potential as therapeutic targets. The in vitro bioassay consisted of assaying the effect of the extracts against denaturation of protein (egg albumin) and measuring the absorbance. To aid functional recovery, we applied in these patients oscilloscopic display of digitally integrated EMG, monitored from malfunctioning primary movers, during attempted execution of movement (sensory feedback therapy). It is unclear whether liver transplantation is associated with an increased incidence of post-transplant head and neck cancer. New dual therapy for primary treatment of Helicobacter pylori infection: A prospective randomized study in Shanghai, China. Subtrochanteric femur fractures result from a variety of mechanisms of injury and underlying pathologies.

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Psychiatric co-morbidity and aftercare among alcoholics: a prospective study of a nationwide representative sample. This understanding often limits surgical exploration of the left hepatic ducts during both curative and palliative surgical procedures. This article attempts to review the surgical methodology and philosophy that have acted as guiding lights in the approach to surgical treatment of baldness over the years and reviews the current role of other techniques in the armamentarium of hair restoration surgeons today. The authors describe a patient with hydatid liver disease successfully treated with albendazole as a alternative treatment to surgery. Central vascular mechanisms underlying structural brain changes may differ between healthy individuals and T2DM. The purpose of this review is to revise the recent literature on the different stem cells populations isolable from fetal liver and candidate to cell therapy of liver diseases and diabetes and to discuss advantages and limitation with respect to other cell sources. At 9 months of follow-up, the patient was voiding well with no evidence of stricture recurrence. Compared with in vitro genotoxicity assay, in vivo genotoxicity assay has been used to verify in vitro assay result and definitely provide biological significance for certain organs or cell types. Gastrointestinal hemorrhage associated with concurrent use of sorafenib and warfarin for hepatocellular carcinoma. Synthesis and activity of sulfonamide-substituted 4,5-diaryl thiazoles as selective cyclooxygenase-2 inhibitors.

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Suppressive effects of acid-forming diet against the tumorigenic potential of pioglitazone hydrochloride in the urinary bladder of male rats. Reverse transcriptase-polymerase chain reaction (RT-PCR), electrophoretic mobility shift assay (EMSA), and other biologic approaches were used for measuring the effect of MB on arthritis and understanding the underlying mechanism. A common genetic variant rs3757318, located in intron of C6orf97, was firstly identified to be associated with breast cancer (BC) risk by a genome-wide association (GWA) study. Many patients with anorexia nervosa drink large quantities of beverages containing caffiene--e.g., coffee and diet cola--which have few calories and suppress the appetite while increasing energy. Comparisons of bacterial patterns present at implant and tooth sites in subjects on supportive periodontal therapy. The relation between fear of progression (FoP) and anxiety disorders remains unclear. Northern blot analysis revealed that BSMAP mRNA is preferentially expressed at a high level in the brain. Structural changes and pain-associated cytokines in the dorsal root ganglia and spinal dorsal horn contribute to prolonged pain. Oral contraceptive pills suppress the hypothalomo-pituitary axis, which can affect the ultrasound and endocrine markers used to examine ovarian reserve.

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