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Blumeta (Metoprolol)

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Blumeta is a selective beta blocker. It slows down the heart which allows it to put less pressure on the body's blood vessels. By slowing down the heart, it also allows the heart to use less oxygen which improves chest pain.

Other names for this medication:
Actiblok, Actocard, Asoprol, Betaloc, Betaone, Blumeta, Cadmet, Dutoprol, Intramet, Macsart, Mepol, Metapro, Metin, Metocare, Metofin, Metolar, Metolex, Metomac, Metoprolol, Metozest, Metpure, Metscore, Metzok, Nexovas, Powermet, Sitelol, Supermet, Telidin, Teliprolol, Toprol, Translol, Vasomet, Vinicor, Vivalol

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Also known as: Metoprolol


Metoprolol is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. A lower blood pressure can reduce the risk of strokes and heart attacks.

Metoprolol is also used to treat severe chest pain (angina) and lowers the risk of repeated heart attacks. It is given to people who have already had a heart attack. In addition, metoprolol is used to treat patients with heart failure.

This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart.

This medicine is available only with your doctor's prescription.


Take Blumeta tablets orally with water. Take Blumeta once or twice a day at the same time. Do not crush or chew it. If you want to achieve most effective results do not stop taking Blumeta suddenly.


If you overdose Blumeta and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Blumeta overdosage: fainting, difficulty, breathing or swallowing, swelling of the hands, feet, ankles, or lower legs, lightheadedness.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Blumeta are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of metoprolol tablets in the pediatric population. Safety and efficacy have not been established.

Appropriate studies have not been performed on the relationship of age to the effects of metoprolol extended-release tablets and extended-release capsules in children younger than 6 years of age. Safety and efficacy have not been established.

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The study shows that isotretinoin has no clinically significant effect on endogenous fibrinolysis. Targeting EGFR-PI3K-AKT-mTOR signaling enhances radiosensitivity in head and neck squamous cell carcinoma. Both flaps have been widely used to provide predictable results, with low morbidity. Low-dose diltiazem might be as effective as the standard dose in controlling rapid AF and reduce the risk of hypotension. A 64-year-old man took levofloxacin 100 mg three times a day from the day before trans-rectal prostate needle biopsy. In the 1990s, however, national security is no longer just a perceived capacity for retaliation but is a process reflecting a much wider view of threat. To compare the cataract surgical rate (CSR) in 2001 with that in 2008 in all Argentinean provinces using current reporting methods and verify the accuracy of CSRs by cross-checking these methods with the number of sold intraocular lenses (IOLs) within the country. Appropriately timed rehabilitation can positively affect surgical outcome of elderly patients by restoring physical abilities and promoting independent function. The effectiveness of the transfection was verified by the rate of DNA synthesis using flow cytometry and by the presence of plasmid DNA in the genomic DNA of the astrocytes using the Southern blot method.

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Three cases of lymph node metastases, one case occurring synchronously with the primary tumor and one synchronously with the first relapse (both in intrathoracic location) and one case of metastasis observed in a laterocervical lymph node subsequently to two thymoma relapses were found. The purpose of this study was to establish ecological validity and initial construct validity of a fire evacuation Virtual Reality Day-Out Task (VR-DOT) environment based on performance profiles as a screening tool for early dementia. The pH dependence of oxidation indicated the formation of a phosphorylated sulfonium ion as an oxidation intermediate. Finally, the use of isoform-selective calpain inhibitors revealed that calpain-2 was involved in RhoA synthesis, whereas calpain-1 mediated RhoA degradation. Therefore, the knowledge of the molecular composition of electrical synapses is fundamental to the understanding of their specific functions. In this ethics committee-approved study, 46 individuals with 49 computed tomographically (CT)-detected and histologically proved lung cancers and 65 patients without nodules at CT were retrospectively included. We determined whether HUS and glomerulonephritis C3 share common genetic susceptibility factors. Therefore, laboratory staff who would like to use commercial products to test blood cultures directly must themselves establish the performance characteristics of the product (keeping in mind the issue of liability) or, preferably, persuade manufacturers to sponsor large-scale controlled clinical trials both to establish performance characteristics and to obtain FDA clearance or approval for such usage of the product.(ABSTRACT TRUNCATED AT 400 WORDS). A serial study of cellular ingrowth and endothelialization was performed.

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Therefore, when considering the least invasive method for reconstruction of this structure, it is important to identify the corresponding bony landmarks on radiographic images. It is accompanied by cognitive, psychological, emotional, and sociocultural changes. To provide surgically controlled data that may allow to replace second-look surgery by non-echoplanar DW-MRI in children. Repair of damaged organelles, stimulation of mitochondrial biogenesis and re-activation of cellular metabolism may accelerate the recovery phase and thus improve clinical outcomes. Evidence for a group II intron in Escherichia coli inserted into a highly conserved reading frame associated with mobile DNA sequences. Spinal cord dose is higher than expected in head and neck radiation. Conventional antiepileptic drugs are frequently ineffective against multiple-seizure types of Lennox-Gastaut syndrome. The purpose of this article is to review the typical imaging features of spondylodiscitis as well as some more atypical and unusual imaging features (early spondylodiscitis, sceptic spondylitis, septic arthritis of facet joints, primary epidural abscess, unusual germs, neonate). Unsuspected exposure to beryllium: potential implications for sarcoidosis diagnoses.

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We hypothesized that if PAS21.5 and PAS25 increased corticospinal excitability by two entirely separate mechanisms then their effects might summate if we intermixed them in the same session. The quality of the cartilage engineered using heterotopic chondrocytes remains partly controversy due to the divergent methodologies and culture conditions used. Of note that, the hopping periods which occur in changes of somatometric and heart rate variability indices, can differ in dependence on the prevailing type of vegetative nervous system. Interaction between hypertension and other cardiovascular risk factors in survival of hemodialyzed patients. Although putative components of Wg- (and by inference Wnt-) mediated signalling pathways have been identified by genetic analysis, the biochemical significance of most factors remains unproven. No animals developed incontinence, and there were no rectal injuries. Decision-making about fitness to stand trial and the consequences of a finding of unfitness are fundamental to the integrity of any criminal justice system. Recommendations focus on the management of hypertrophic scars and keloids. The technique can be used to identify the most efficient way to disturb a system such that it transits from one stable state to another.

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Treatment options include total graft excision and extra-anatomic bypass or in situ replacement of the graft. Smaller fragments of mitochondrial DNA may appear in the nucleus even more frequently. The occurrence of PSIs and HACs is associated with increased mortality and hospital costs after stroke. Isolated killifish (Fundulus heteroclitus) renal tubules transfected with pEGFP-C3/rROAT1 showed marked basal and lateral membrane-associated fluorescence, but no detectable signal in the nucleus or the apical pole of tubule cells. Both WT and AT(2) receptor knockout mice were treated for 7 days with either ACE inhibitors or ARBs. A training set of 309 protein-ligand protein X-ray structures has been used to generate interface propensities for the triplets, which can be used to predict their involvement in ligand-binding interactions.

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DtxR, an iron-dependent transcriptional repressor that regulates the expression of siderophore gene clusters in Thermobifida fusca. The recommendations are discussed in light of the different purposes outlined above. Many plethodontid species in southern Appalachia exist in high elevation habitats that may be at or near their thermal maxima, and may also have limited dispersal abilities across warmer valley bottoms. Depressive symptoms are associated with obesity, and are more common in women. We propose that changes in NEDDylation may modulate vascular endothelial function in part through alterations in the proteasomal degradation of HDAC2. Monitoring of hematopoietic chimerism after transplantation for pediatric myelodysplastic syndrome: real-time or conventional short tandem repeat PCR in peripheral blood or bone marrow?. Rectourethral fistulas are uncommon, usually iatrogenic injuries that are demanding to treat. To provide sufficient jaw-to-jaw alveolar ridge (interarch) relationship information for both restorative and surgical treatment decision-making, this article introduces a new interarch alveolar ridge relationship classification system. Solar energy technologies today generate heat or electricity, while the large majority of our energy is used in the form of fuels.

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Hepatocyte growth factor (HGF) receptor expression is inducible and is part of the delayed-early response to HGF. The radiation response of sarcomas by histologic subtypes: a review with special emphasis given to results achieved with razoxane. The secretion of vascular endothelial growth factor by eight fresh cervical cancer cell preparations (four adenocarcinomas and four squamous cell carcinomas) and four established squamous cell lines was evaluated using a sensitive enzyme-linked immunosorbent assay in vitro. Flat spots, grey or black sloughs, and clear ulcer bases are not treated endoscopically. For this reason, many studies have been undertaken on the structure-activity relationships of natural thrombin inhibitors, and a large amount of detailed information has been obtained by the crystal structures of these inhibitors when complexed with thrombin. The majority of patients showed improvement after receiving increased doses of infliximab, without an increased risk of adverse events. This role is consistent with the ability of osteocytes to respond to and transmit signals over long distances while embedded in a calcified matrix. On the other hand, transient transfection of the dominant-negative construct of raf-1 rescued serum-deprived Ha-ras-transformed brown adipocytes from apoptosis, decreasing the percentage of hypodiploid cells, the external display of phosphatidylserine, and the DNA laddering. These findings suggest that abnormally low Hcrt-1 is not a likely cause of fatigue in FMS. We defined STIs as one or more medical claims for any of the following infections in a given quarter: chlamydia, gonorrhea, herpes, human immunodeficiency virus or AIDS, or syphilis.

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Clinicians and public health practitioners should consider developing similar systems. We present a one-bead coarse-grained model that enables dynamical simulations of proteins on the time scale of tens of microseconds. Surface plasmon resonance experiments demonstrated the ability of apical and C-terminal fragments of P1 to interact. elegans is a simple multicellular model organism that mimics many fundamental features of human biology and has been used to define many biological properties conserved through evolution. There were no gender differences in factors associated with terminating the relapse episodes. A key structural transition occurs on addition of residues Phe-50 and Val-51 and fragment (1-60) is largely folded. In this review, the interaction of several TKIs, currently in clinical use or being developed in clinical trials, with the MDR-related ABC transporters, in particular ABCB1, ABCC1 and ABCG2, will be discussed. The hydraulic permeability of single-layer fibrous media is studied through two-dimensional (2D) and three-dimensional Navier-Stokes based flow simulations. However, the V wave is often increased in patients without or with no significant mitral regurgitation.

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The influence of epitope availability on atomic-force microscope studies of antigen-antibody interactions. The maintenance of immune function by androgen deficiency does not seem to be related to changes in the release of corticosterone. This phenomenon is due to the combined T2-shortening effects of two paramagnetic substances, methemoglobin and gadolinium, which cause the signal reduction produced by the T2 effects to occur at lower concentrations of gadolinium. Detection of non-diploid cells in premalignant and malignant oral lesions using combined morphological and FISH analysis - a new method for early detection of suspicious oral lesions. The use of PVP increased the aqueous solubility of the nonoxynol-9 formulations containing oligomers 1 to 18 and 8 to 10 slightly. TNFRp55-mediated immune mechanisms prevent ReA development after oral infection with Y. Nerve conduction velocities were moderately slowed, and amplitudes of sensory and motor potentials were decreased. Validation of the method reveals that it is specific, reproducible, precise, and robust.

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A recent structure based design project yielded nine co-crystal structures of pyrrolidinone inhibitors bound to the viral protein 35 (VP35). Hence, a key question facing a clinician working from a cognitive behavioural perspective is which theory should be chosen as the basis of the conceptualisation with a particular client?. We provide a list of shared policy goals, targets and elements for HPAI preparedness, response and recovery. To gain more insight into the phenomenon of Tako-Tsubo cardiomyopathy (TTC), the purpose of the present study was to investigate the myocardial structure in the acute phase of TTC and after functional recovery. In the aneurysm located at the renal artery, the technique of stent-assisted coils embolization was preferred to avoid coils migration due to its wide neck. Lipid peroxidation marker mainly thiobarbituric acid reactive substances (TBARS) and antioxidant enzymes namely superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), glutathione-S-transferase (GST) and glucose-6-phosphate dehydrogenase (G6PDH) activities and non-enzymatic antioxidants such as reduced glutathione, ascorbic acid and alpha-tocopherol levels were studied. Despite the use of potent antibiotics and intensive supportive care, mortality remains high among septic shock patients, especially those with endotoxemia.

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However, pulse gradient spin echo nuclear magnetic resonance (PGSE NMR) measurements clearly indicated a change in hydrodynamics including increased pore scale mixing. An accurate assessment of deep dermal burns within the first week after burn is still an unresolved clinical problem. Clinician practices for the management of amenorrhea in the adolescent and young adult athlete. This article synthesizes nine years of published research on the use of acupuncture as an adjunct treatment for the management of cancer pain. In competitive binding assays, chimeric MAbs and their Fab fragments showed identical specificity to human CEA epitopes, as compared to the parental MAbs or Fab fragments. Differential response on proximal functioning and distal atrophic colon.

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We report a 12-year-old with intracerebral hematoma and subarachnoid hemorrhage secondary to the rupture of a peripheral lenticulostriate artery aneurysm. A total of 219 (20-80 years old) healthy subjects were enrolled in this cross-sectional study. It is concluded that in patients with prolapsed lumbar intervertebral discs necessitating operation, the canal tends to be narrower than normal, and such narrowing enhances the effect of any disc protrusion leading to severe symptoms of backache and sciatica. Oxalic acid and diacylglycerol 36:3 are cross-species markers of sleep debt. It is suggested that the thermoregulation of the embryo has a thermal induction-like effect starting from ED14 and increasing gradually till hatching. Furthermore, anti-ischemic therapy may improve left ventricular function and clinical outcomes in patients with heart failure resulted from DCM. Myoclonic epilepsy evolved into West syndrome: a patient with a novel de novo KCNQ2 mutation. From a total 9,104 subjects, 700 were assigned to the COPD group, 560 to the asthma group, 210 to the overlap syndrome group, and 7,634 to the NOD group.

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Pouch can not compensate the whole colonic absorptive function and patients have to live with some of functional abnormality. Adding NRT to BT leads to large increases in efficacy, while adding BT to NRT is of uncertain value. To study the mechanism of action of BCG against transitional cell carcinoma of the bladder from the immunological standpoint, we observed time-course changes in the serum and urine levels of tumor necrosis factor (TNF-alpha) and interleukin-2 (IL-2) before and after an intravesical BCG instillation in 16 patients with superficialis transitional cell carcinoma. The Z-lengthening group showed a notable presence of equinus and a notable lack of push-off work initially and had a significant decrease in equinus and a significant increase in push-off work at follow-up. Development of a novel liquid bead array human papillomavirus genotyping assay (PGMY-LX) and comparison with linear array for continuity in longitudinal cohort studies. The relative immunogenicity of the H-7.1 alloantigen has been shown in a previous communication to be regulated by a gene in the D region of the mouse major histocompatibility (H-2) complex.

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We also used a normalized cross-correlation method in order to test the similarity of the VECP components. Estimation of tumor size and detection of isolated residual in situ carcinoma are fare. Most published research concerns the development of tools to be used in a disease-specific manner for clinical trials. the superior properties that differentiate improved follow-on drugs (best-in-class). Original and review articles, and consensus documents with elevated level of evidence for VDD-related clinical decisions on the health of pregnant women and their children, as well as articles on the influence of ViD on epigenetic mechanisms of fetal programming of chronic diseases in adulthood were selected among articles published on PubMed over the last 20 years, using the search term VitD status, in combination with Pregnancy, Offspring health, Child cyclophosphamide all brand name outcomes, and Programming. There appears to be an elevated risk of family history of substance use disorders in MOH patients, and an increased risk of MOH in patients with diagnosed personality disorders.

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Liver cirrhotic patients with hepatic encephalopathy have poor prognosis. We describe CellTracker, a software tool designed for the automated measurement of the cellular location and intensity of fluorescently tagged proteins. A working group of five individuals from the PRACTIHC group was formed to develop content for the tool. In addition, development of instruments capable of accurately quantifying adsorbed gases and volatile organic compounds is needed. Consistent use of evidence-based health literacy practices by front-line nurses offers the potential for transformations in nursing care through stronger patient-nurse interactions and health system partnerships. Increased prevalence cleocin gel 1% of oesophagitis has been reported following eradication of Helicobacter pylori. Patients with ulcers and/or multiple lesions should be evaluated to rule out immunosuppression or infection by Leishmania species from other parts of the world. The interesting findings were that the healing was observed even in the presence of two roots, including preservation of the vitality of the pulp.

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Unlike the structurally related MAPK pathway, the stress induced kinases are not required for mitogenesis and instead induce growth arrest. Risk of insulin accumulation (stacking) with use of novel ultralong-acting insulin formulations. To develop and utilize a new infant respiratory chamber for simultaneous measurements of EE (kJ/d), preprandial BMR (kJ/d), SMR (kJ/d) and an index of PA (oscillations/min/kg body weight) in infants with a variety of metabolic disorders, for up to four hours in a hospital setting, while allowing parental interaction in a comfortable environment. Unruptured rudimentary horn pregnancy presenting with acute haemoperitoneum with combined intrauterine pregnancy: A case report. mutans to saliva-coated hydroxyapatite, and concomitantly to determine the content of free sialic acid.

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There is no evidence for routine knee arthroscopy in the treating of PFP. Nasopharyngeal carcinoma-associated Epstein-Barr virus-encoded oncogene latent membrane protein 1 potentiates regulatory T-cell function. Using the petrous part of the temporal bone to estimate fetal age at death. Diagnostic utility of brain-natriuretic peptide for left ventricular diastolic dysfunction in asymptomatic type 2 diabetic patients. The system provides an effective 3D monitoring and can be used in a wide range of environmental applications such as agriculture, bushfires, mining studies, zoology and botanical zyrtec syrup dosage gsk studies using a ubiquitous low cost technology. As hydroxyurea (HU), sodium phenyl butyrate (SPB) is known to induce fetal hemoglobin (HbF) expression and thus shows potentials for sickle-cell disease (SCD) treatment. The overwhelming majority of patients are able to retain the CISC skill weeks after being taught in the clinic. Nevertheless, the increased protein surface hydrophobicity of CC49-TCO(1) led to a relatively rapid blood clearance and concomitant reduced tumor uptake compared to native CC49 antibody. Analysis of HPC families with members diagnosed with primary renal cell carcinoma demonstrates suggestive linkage to chromosome 11p11.2-q12.2. We interpret these data as a microtubule rearrangement, rather than erosion, because total tubulin flourescence was not different between groups.

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