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Bitensil (Enalapril)
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Bitensil

Bitensil is a prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure. It is indicated for the management of essential or renovascular hypertension. It is indicated as monotherapy or in combination with other antihypertensive agents, such as thiazide diuretics, for an additive effect.

Other names for this medication:
Acepril, Acetensil, Anapril, Angiotec, Atens, Auspril, Bajaten, Ciplatec, Convertase, Corodil, Cosil, Daren, Denapril, Ecaprilat, Ecaprinil, Ednyt, Enadura, Enaladex, Enaprotec, Encardil, Ephicord, Epril, Eupressin, Fibrosan, Glioten, Hasitec, Hipopril, Insup, Jutaxan, Kalpiren, Lowtril, Maxen, Minipril, Neotensin, Nuril, Olivin, Pharmapress, Pressitan, Presuren, Prilace, Pulsol, Renipril, Selis, Spaciol, Tenaten, Tensapril, Unipril, Vapresan, Vimapril, Vitobel

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Also known as: Enalapril

Description

Enalaprilat injection is used to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled .

Enalaprilat works by blocking an enzyme in the body that is necessary to produce a substance that causes blood vessels to tighten. As a result, the blood vessels relax. This lowers blood pressure and increases the supply of blood and oxygen to the heart .

This medicine is available only with your doctor's prescription .

Dosage

Usual Adult Dose for Hypertension:

Initial dose: 5 mg orally once a day Maintenance dose: 10 to 40 mg orally per day as a single dose or in 2 divided doses Maximum dose: 40 mg orally daily as a single dose or in 2 divided doses In combination with diuretics: Initial dose: 2.5 mg orally once a day If feasible, the diuretic should be discontinued 2 to 3 days prior to initiation of therapy with enalapril. If required, diuretic therapy may be gradually resumed.

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 2.5 mg orally once a day Maintenance dose: 2.5 to 20 mg daily in 2 divided doses Maximum dose: 40 mg orally per day in 2 divided doses Comments: -Treatment is usually combined with diuretics and digitalis. -Doses should be titrated upward, as tolerated, over a period of a few days or weeks.

Usual Adult Dose for Left Ventricular Dysfunction:

Initial dose: 2.5 mg orally twice a day Maintenance dose: 20 mg orally per day in 2 divided doses Comments: -After the initial dose, the patient should be observed for at least 2 hours and until blood pressure has stabilized for at least an additional hour. -If possible, the dose of any concomitant diuretic should be reduced which may diminish the likelihood of hypotension.

Usual Pediatric Dose for Hypertension:

Children 1 month to 17 years: Initial dose: 0.08 mg/kg/day (up to 5 mg) in 1 to 2 divided doses. Adjust dosage based on patient response. Maximum dose: Doses greater than 0.58 mg/kg (40 mg) have not been evaluated in pediatric patients. Comment: -Not recommended in neonates and in pediatric patients with glomerular filtration rate less than 30 mL/min, as no data are available.

Detailed Bitensil dosage information

Overdose

If you overdose Bitensil and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Bitensil overdosage: fainting, dizziness.

Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bitensil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Enalapril can decrease sweating and you may be more prone to heat stroke.

Drinking alcohol can further lower your blood pressure and may increase certain side effects of enalapril.

Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

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The mean difference in peak flow was greater on the non-working than on the working days and was not related to age, sex, years of exposure, smoking or atopy. Ixeris sonchifolia ( drug classification of risperdal Bunge) Hance, a folk medicine, has been widely used in China for its anti-inflammatory and haemostatic effects. Certain Bcl-2 family members promote cell survival, whereas others promote apoptosis. A rationale exists for developing the field of nutrition economics which could offer a better understanding of both nutrition, in the context of having a significant influence on health outcomes, and economics, in order to estimate the absolute and relative monetary impact of health measures. We evaluated the involvement of reactive oxygen species and antioxidant defenses during intestinal remodeling and tail regression of tadpoles of Xenopus laevis.

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Primary aorto-duodenal fistula: evaluation with computed tomography. A soluble form of RANK as well as osteoprotegerin/osteoclastogenesis inhibitory factor, a decoy receptor of ODF, blocked OCL formation and prevented the survival, multinucleation, and pit-forming activity of pOCs induced by sODF. Histologic confirmation of acute rejection detected by urine cytology in pancreas transplant recipients. Southeast Asia is a biodiversity hotspot that harbours many species of rodents, including some that live in close contact with humans. Obesity is a well-recognized risk factor for type 2 diabetes mellitus (DM) among young and middle-aged adults in South Korea. Recently, lipopolysaccharide (LPS), a major biologically active agent of Gram-negative bacteria, was shown to mediate cellular activation by a member of the human Toll-like receptor family, Toll-like receptor (TLR) 2. They have been widely used as models to identify and understand the molecular mechanisms of natural anoxia tolerance and the molecular basis of the hypoxic/ischemic injuries that occur in oxygen-sensitive systems and underlie medical problems such as heart attack and stroke. The structure of the polymer network and the behavior of water accommodated in the network are important factors governing the chemical and physical properties of gel materials. Two other patients (three ears) also had enlarged VA and ES as well as cochlear anomalies, but did not have episodes of sudden hearing loss and vertigo.

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An urgent CT of the abdomen and pelvis was performed to rule out incarcerated inguinal hernia. We report a case series of ten patients from a tertiary epilepsy center, where a clear history was obtained of physical exercise as a reproducible trigger for seizures. A unique cohort of pluripotency genes including Esrrb require both stimuli for activation. Metabolic syndrome was diagnosed according to the NCEP-ATPIII criteria. Pemphigus vulgaris is an autoimmune intraepithelial bullous disease resulting from pathogenic IgG antibodies toward desmoglein antigens that often requires long-term immunosuppressive therapy for control of disease symptoms. A single pump laser is employed and a homogeneous magnetic field is utilized to avoid cancellation effects through the nonlinear Zeeman effect. Recently, techniques for polymerase chain reaction (PCR) using fixed tissue have been described that to our knowledge have not been applied to LELCS. The clinical results and the physiological and hemodynamic measurements will be presented in detail.

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