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Biotrim (Trimethoprim)

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Biotrim (sulfamethoxazole / trimethoprim) is absorbed by the body and begins to kill bacteria within 1 to 4 hours after taking your dose. For more common problems like urinary tract infections and ear infections, most people will start to feel relief after a few days.

Other names for this medication:
Actrim, Bactricid, Bactropin, Balsoprim, Biseptrin, Comox, Cotrimoxazol, Ectaprim, Gentrim, Infectrim, Lapikot, Metoxiprim, Noxaprim, Primazole, Sanprima, Sepmax, Sigaprim, Suftrex, Sulfatalpin, Sulfatrim, Sulmetrim, Sulphytrim, Sumetrolim, Sutrim, Tabrol, Tagremin, Trimecor, Trimexazol, Trimol, Trimoxsul, Tritenk

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Also known as: Trimethoprim


This medication is used to treat a wide variety of bacterial infections. It is also used to treat a certain type of pneumonia (pneumocystis pneumonia) in patients with a weakened immune system. This medication is a combination of 2 antibiotics: sulfamethoxazole and trimethoprim. It works by stopping the growth of bacteria and the pneumocystis fungus.


Adults: The usual adult dosage in the treatment of urinary tract infections is 1 Biotrim DS (double strength) tablet or 2 Biotrim tablets every 12 hours for 10 to 14 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.

Children: The recommended dose for children with urinary tract infections or acute otitis media is 40 mg/kg sulfamethoxazole and 8 mg/kg trimethoprim per 24 hours, given in two divided doses every 12 hours for 10 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include loss of appetite, vomiting, fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Biotrim DS dosage information

Side effects

The most common side effects associated with Biotrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Before taking sulfamethoxazole with trimethoprim, tell your doctor or pharmacist if you are allergic to sulfa medications or trimethoprim; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, certain blood disorders (such as porphyria, anemia due to folate vitamin deficiency), history of blood disorders caused by trimethoprim or sulfa medications, vitamin deficiency (folate or folic acid), severe allergies, asthma, decreased bone marrow function (bone marrow suppression), a certain metabolic disorder (G6PD deficiency), underactive thyroid, mineral imbalances (such as high level of potassium or low level of sodium in the blood). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths or sunlamps. Use a sunscreen and wear protective clothing when outdoors. If you have diabetes, this product may affect your blood sugar levels. Check your blood sugar levels regularly as directed by your doctor. Tell your doctor immediately if you have symptoms of low blood sugar (see Side Effects section). Your doctor may need to adjust your diabetes medication, exercise program, or diet. Older adults may be more sensitive to the side effects of this drug, especially skin reactions, blood disorders, easy bleeding/bruising, and a high potassium blood level. Patients with AIDS may be more sensitive to the side effects of this drug, especially skin reactions, fever, and blood disorders. This medication is not recommended for use during pregnancy especially near the expected delivery date because of possible harm to the unborn baby. Consult your doctor for more details. This drug passes into breast milk. While there have been no reports of harm to healthy infants, this drug may have undesirable effects on infants who are ill or premature or have certain disorders (jaundice, high blood levels of bilirubin, G6PD deficiency). Therefore, breast-feeding is not recommended for infants with these conditions. Consult your doctor before breast-feeding.

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Two presentations of upper lid migration of rigid gas-permeable contact lenses. Food intake and weight data were collected over the study period on each patient. Human and mouse XAP-5 and XAP-5-like (X5L) genes: identification of an ancient functional retroposon differentially expressed in testis. This review focuses on recent evidence that identifies potential extracellular and cellular mechanisms that may be involved in the tolerance of ectomycorrhizal fungi to excess metals in their environment. Inhibition of neuronal nitric oxide synthase by 4-amino pteridine derivatives: structure-activity relationship of antagonists of (6R)-5,6,7,8-tetrahydrobiopterin cofactor. Increasingly it is being realized that biologically active phytochemicals modulate TRAIL induced apoptosis, as evidenced by cell-based studies.

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Rare cases of descending necrotizing mediastinitis can occur following oral cavity and pharynx infection or can be a complication of pancreatitis. Better soft tissue preservation in the early postoperative period was achieved using the PBI approach compared with the IS approach. A systematic search was performed to evaluate the impact of air pollutants on fertility. King Edward VIII Teaching Hospital, University of Natal, Durban, South Africa. The bacterial gene for neomycin resistance introduced in the genome by enalapril 10mg tablets P-mediated transformation renders larvae resistant to G418 and able to grow to fertile adults. The membranes in all three show a considerable excess of spectrin dimers over tetramers in spectrin extracts. Nonreplication of Jamestown Canyon and Keystone (California group) viruses in tabanids (Diptera: Tabanidae).

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The observed contrast ratios vary in value from the Rayleigh limit of 0.52 to in excess of 2, suggesting that the contrast ratio could be useful in optical coherence tomography, particularly when imaging in ultrahigh-resolution regimes. This novel resveratrol analog was able to inhibit melanoma tumors in a primary tumor model alone and in combination with dacarbacine, an anticancer compound that is used for melanoma treatment. Ultrastructure of the uterine glands and the overlying trophoblast. ATCC 51142, a prototypic member of this group, revealed many interesting metabolic attributes. In particular, the problem of delayed aneurysmal rupture can be avoided with this technique. In order to assess ecological validity of executive function (EF) tests and the impact of EF dysfunction on functional status in elderly subjects with moderate and severe subcortical white matter hyperintensities (WMHs), we made a correlation analysis between EF scores and two measures of Instrumental Activities of Daily Living (IADL). Enzyme-linked immunosorbent assay (ELISA) microarray technology can simultaneously quantify levels of multiple proteins and, thus, has the potential to accelerate validation of protein biomarkers for clinical use.

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The pK(a) -cooperative aims to provide a forum for experimental and theoretical researchers interested in protein pK(a) values and protein electrostatics in general. Distinct genetic characteristics of Sri Lankan Rattus and Bandicota (Murinae, Rodentia) inferred from mitochondrial and nuclear markers. Relationships between two levels of aureomycin-sulphamethazine supplementation and acquisition of resistance to ovine coccidiosis. In 15 sibships with two or more affected sibs, cleft palate, and parental HLA haplotypes assorted independently in the affected sibs, providing evidence against close linkage of this phenotype. Spatial management around these islands is complex, particularly in the context of commercial fisheries that exploit some of these living resources.

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Community Environmental Monitoring Program: a case study of public education and involvement in radiological monitoring. These encompass methods applicable to studies in vitro, in situ, and in vivo. Tension pneumocephalus related to radiotherapy for nasopharyngeal carcinoma. The objective of the prevention of Mother-to-Child Transmission (pMTCT) cascade analysis tool is to provide frontline health managers at the facility level with the means to rapidly, independently and quantitatively track patient flows through the pMTCT cascade, and readily identify priority areas for clinic-level improvement interventions. Temporal assessment of ribose treatment on self-assembled articular cartilage constructs.

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