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Biortan (Losartan)

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Biortan and associated names, 12,5 mg, 25mg, 50 mg, 100 mg, film-coated tablets is an orally active angiotensin II (Ang- II) receptor antagonist. Biortan acts on the AT1 receptor subtype and blocks the effect of Ang-II in the renin angiotensin system (RAS) cascade. Biortan is indicated for the treatment of hypertension.

Other names for this medication:
Angibloc, Asart, Cardon, Corus, Cosart, Covance, Eklips, Forzaar, Lifezar, Lohyp, Loplac, Lorista, Losadel, Losagen, Losamet, Losart, Losartas, Losartax, Lospre, Lostankal, Loxibin, Lozitan, Maxartan, Normatens, Ostan, Ozarium, Prelow, Resilo, Sanipresin, Sedeten, Tacardia, Tensaar, Tiasar

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Also known as: Losartan


Biortan (losartan potassium) is an angiotensin II receptor blocker acting on the AT1 receptor subtype. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Biortan is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

Biortan is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

Biortan 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively. Biortan 25 mg, Biortan 50 mg, and Biortan 100 mg may also contain carnauba wax.


Take Biortan tablets orally with or without food. Do not crush or chew it. Take Biortan once or twice a day at the same time. If you want to achieve most effective results do not stop taking Biortan suddenly.


If you overdose Biortan and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Biortan overdosage: fainting, feeling lightheaded, rapid heartbeat.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Biortan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Drinking alcohol can further lower your blood pressure and may increase certain side effects of Biortan.

Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

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Estimations of internal consistency and scale validity were conducted using contrast-group comparisons and convergent validity, with satisfactory results. We derive first-order expansions for the possible patterns in the presence of an external morphogen and show how both stripes and spots are affected. We review the existing literature on this topic and highlight outstanding questions and potential future directions that should clarify the impact of NDPK on the different cytoskeletal systems. Memory CD44(int) CD8 T cells show increased proliferative responses and IFN-gamma production following antigenic challenge in vitro. Deubiquitinases in cancer: new functions and therapeutic options. Locoregional breast cancer recurrence is a relatively rare event, occurring more frequently in patients diagnosed with more advanced stages of cancer and those with inflammatory features.

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