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Bionil (Glibenclamide)
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Bionil

Bionil belongs to the class of drugs known as sulfonylureas. It lowers blood sugar by causing the release of your body's natural insulin. Bionil is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. It may also be used with other diabetes medications..

Other names for this medication:
Betanase, Betrol, Bionil, Codica, Combidos, Daocon, Daonil, Diabnil, Diolin, Duotrol, Euglucon, Eumet, Giclamide, Glibact, Glibet, Glibson, Glifil, Glimsug, Glinil, Glitrac, Glucomin, Gluconil, Glucored, Glucosafe, Glucosil, Glunil, Glutowin, Glybenclamide, Glyboral, Glybovine, Glycurb, Iscept, Metclam, Metica, Monomet, Pionorm, Secrin, Sugatrol, Sugnil, Symet, Triglucored, Triglycomet

Similar Products:
Aceon, Precose, Sovaldi, Deltasone, Caverta, Vasotec, Bromogen, Ection, Levomax, Tenola, Noctaderm, Azona, Latiln, Zerinorm,

Also known as: Glibenclamide

Description

Bionil is used to treat high blood sugar levels caused by type 2 diabetes. In type 2 diabetes, your body does not work properly to store excess sugar and the sugar remains in your bloodstream. Chronic high blood sugar can lead to serious health problems in the future.

Proper diet is the first step in managing type 2 diabetes, but often medicines are needed to help your body. Bionil belongs to a class of medicines called sulfonylureas. It causes your pancreas to release more insulin into the blood stream. Bionil, micronized may be used alone or with another oral medicine such as metformin.

Bionil, micronized is available only with your doctor's prescription.

Dosage

Take Bionil, micronized exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Carefully follow the special meal plan your doctor gave you. This is the most important part of controlling your condition, and is necessary if the medicine is to work properly. Also, exercise regularly and test for sugar in your blood or urine as directed.

Do not change to another brand without checking with your doctor. The number of tablets that you take depends on the brand and strength of the medicine. If you refill your medicine and it looks different, check with your pharmacist.

The dose of Bionil, micronized will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of Bionil, micronized. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For type 2 diabetes: For oral dosage form (micronized tablets): Adults—At first, 1.5 to 3 milligrams (mg) once a day taken with breakfast or the first main meal. Some patients may start at 0.75 mg per day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 12 mg per day. Children—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause severe hypoglycemia or lactic acidosis.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Side effects

The most common side effects associated with Bionil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For Bionil, micronized, the following should be considered:

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Cloning, sequencing and heterologous expression of pyrogallol-phloroglucinol transhydroxylase from Pelobacter acidigallici. The occurrence of a coccidian parasite, Cryptosporidium, among birds in the Kuala Lumpur National Zoo was investigated in this study. However, rectal biopsy is still suggested for disease confirmation given its low PPV. MMR expression was then investigated immunohistochemically in feline lymphomas. This is crucial for an increased understanding of the dynamics of the Earth system. Moreover, 60-minute sevoflurane preconditioning significantly attenuated neurological deficits and infarct volume in rats at 4 days after cerebral ischemia. Other tumours were: reticuloses, malignant lymphomas, lung adenomas, subcutaneous fibrosarcomas, parenchymal adenomas, hemangiomas and one angiosarcoma of the liver, intestinal adenocarcinomas and one granulosa cell tumour of the ovary.

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We applied recent knowledge from gonadal germ cell tumours and analysed expression of a wide panel of stem cell-related proteins (C-KIT, OCT-3/4 (POU5F1), AP-2gamma (TFAP2C), and NANOG) and developmentally regulated germ cell-specific proteins (including MAGE-A4, NY-ESO-1, and TSPY). Repair for mitral valve aneurysm using autologous pericardium: a case of our experience. Vasodilator therapy has been shown to be beneficial in improving cardiovascular function in some patients. Comorbid psychiatric disorders may also be present in these patients. Mildronate in a dose 1 g/day per os may be beneficial for LQ of CHF patients. The activated Akt kinase pathway can prevent the death of nerve cells and exhibit neuroprotective effects in the brain after stroke. In addition to the protective effects of chiropractic in the unadjusted model, the propensity score results indicate a significant protective effect of chiropractic against decline in reaching. Modulation of glutathione transferase P1-1 activity by retinoic acid in neuroblastoma cells.

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Reconstruction of the abdominal wall for incisional hernia repair. Chronic neuroleptic treatment reduces endogenous kynurenic acid levels in rat brain. Intracellular MMP2 expression and activity were determined by quantitative reverse transcription polymerase chain reaction (RT-PCR), Western blotting, and zymography, respectively. Dynamic generation of diagnostic knowledge from a database of well defined case clinical records. The purpose of this study was to clarify the positional relationship between the crown contour and the pulp chamber using micro-CT system for restorations of maxillary second deciduous molar. We conclude by discussing how one particular theoretical rationale can be intersected with key SenseCam capabilities to define priorities for ongoing and future SenseCam research. It will take an independent governor to change New Jersey for the better. One hundred thirty-eight neuropsychiatric outpatients were rated according to relevant behavioral parameters of violence. This paper outlines the goals, structure, and expected outcomes for the one-year Fellowship in Graduate Medical Education Administration program. We have found that (1) both conductance values decrease exponentially with the molecular length with an identical decay constant, beta approximately equal to 0.84 A(-1), but with a factor of 5 difference in the prefactor of the exponential function.

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