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Bigtin

Bigtin is an anti-epileptic drug, also called an anticonvulsant. It affects chemicals and nerves in the body that are involved in the cause of seizures and some types of pain. Bigtin is used together with other medicines to treat partial seizures in adults and children at least 3 years old.

Other names for this medication:
Alnacob, Benatin, Carecobal, Cobanerve, Doloneuron, Gabacent, Gabalept, Gabamid, Gabaneuron, Gabanez, Gabastar, Gabatin, Gabpam, Gabtin, Gapen, Gapin, Mecospan, Mecova, Melife, Metgaba, Micknerve, Mycolin, Nervibrain, Nervicin, Nervoday, Neupent, Neurocon, Neuronti, Neuropin, Neurotop, Nurotin, Orogab, Renerve, Templer

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Also known as: Gabapentin

Description

Bigtin (gabapentin) is an anti-epileptic drug, also called an anticonvulsant. It affects chemicals and nerves in the body that are involved in the cause of seizures and some types of pain.

Bigtin is used in adults to treat neuropathic pain (nerve pain) caused by herpes virus or shingles (herpes zoster).

Bigtin is also used to treat seizures in adults and children who are at least 3 years old.

Use only the brand and form of gabapentin your doctor has prescribed. Check your medicine each time you get a refill to make sure you receive the correct form.

Dosage

Usual Adult Dose for Epilepsy:

Initial dose: 300 mg orally on day one, 300 mg orally 2 times day on day two, then 300 mg orally 3 times a day on day three Maintenance dose: 300 to 600 mg orally 3 times a day Maximum dose: 3600 mg orally daily (in 3 divided doses) -Maximum time between doses in the 3 times a day schedule should not exceed 12 hours Comment: -May be taken with or without food. -Half-tablets not used within 28 days of breaking the scored tablet should be discarded. Use: Adjunctive therapy in the treatment of partial onset seizures, with and without secondary generalization

Usual Adult Dose for Postherpetic Neuralgia:

-Initial dose: 300 mg orally on day one, 300 mg orally 2 times day on day two, then 300 mg orally 3 times a day on day three -Titrate up as needed for pain relief -Maximum dose: 1800 mg per day (600 mg orally 3 times a day) COMMENT: -May be taken with or without food. -Half-tablets not used within 28 days of breaking the scored tablet should be discarded.

Usual Pediatric Dose for Epilepsy:

Less than 3 years: Not recommended Greater than or equal to 3 and less than 12 years: Starting Dose: Ranges from 10 to 15 mg/kg/day in 3 divided doses Effective Dose: Reached by upward titration over a period of approximately 3 days; the effective dose in patients 5 years of age and older is 25 to 35 mg/kg/day in divided doses (3 times a day). The effective dose in pediatric patients ages 3 and 4 years is 40 mg/kg/day and given in divided doses (3 times a day). Gabapentin may be administered as capsule, or tablet, or using combinations of these formulations. Dosages up to 50 mg/kg/day have been well tolerated in a long term clinical study. The maximum time interval between doses should not exceed 12 hours. Greater than 12 years: -Initial dose: 300 mg orally on day one, 300 mg orally 2 times a day on day two, then 300 mg orally 3 times a day on day three -Maintenance dose: 900 to 1800 mg orally in 3 divided doses; the dose may be increased up to 1800 mg/day. Dosages up to 2400 mg/day have been well tolerated in long term clinical studies. Doses of 3600 mg/day have also been administered to a small number of patients for a relatively short duration, and have been well tolerated. The maximum time between doses in the three times a day schedule should not exceed 12 hours. Use: Adjunctive therapy in the treatment of partial onset seizures, with and without secondary generalization in patients 3 years of age and older

Detailed Bigtin dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Bigtin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

Avoid taking an antacid within 2 hours before you take Bigtin. Antacids can make it harder for your body to absorb gabapentin.

Avoid drinking alcohol while taking Bigtin.

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A novel CLN2/TPP1 mutation in a Chinese patient with late infantile neuronal ceroid lipofuscinosis. Management of cardiac surgery patients is a very standardized procedure in respective local institutions. The incidence of accidental pregnancy fell dramatically after the first year of use. We show that diminished expression of Cyp26a1, a retinoic acid inactivating enzyme, and concomitant elevation of retinoic acid activity in the caudal region of Gdf11(-/-) embryos may account for this phenomenon. Surgical conservative procedures and intravenous use of sulprostone (Nalador) failed to control haemorrhage. It is very important that the indications and time of retransplantation are carefully selected. Self-esteem was the strongest contributing factor differentiating dieters and nondieters. Soluble factors from the target organ enhance tumor cell angiogenesis: role of laminin SIKVAV sequence.

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Canine visceral leishmaniasis in Teresina, Brazil: Relationship between clinical features and infectivity for sand flies. Achievement of metabolic targets for diabetes by English primary care practices under a new system of incentives. A novel phospholipase C inhibitor and phorbol esters reveal selective regulation of thrombin- and parathyroid hormone-stimulated signaling pathways in rat osteosarcoma cells. Multivariate analysis showed that Cox-2 remained a significant prognostic factor for survival independent of tumor size, nodal status, ER, Her2/neu, and grade. Hypertrophy of the right heart after experimental lung resection. In DsbA, the Cys30 thiol group is shown to be reactive toward alkylating reagents down to pH 4 and to be fully ionized, on the basis of the UV absorbance of the thiolate anion at 240 nm. When the influence of head growth was distinguished for different periods, only prenatal growth and growth during infancy were associated with subsequent IQ.

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Chronic electrophysiological recordings in free-feeding Aplysia showed that as the meal progressed, food elicited fewer ingestive responses and simultaneously increased the number of egestive responses. But prolonged exposure to serum concentration close to the MIC is associated with the emergence of resistance. Results suggested that the occupational health activities focused on primary prevention had been effective. Growth velocity (GV), maximum GH dose, IGF-BP3, and changes in height SDS, IGF-1 SDS, and GV were compared. The purpose of this study was to investigate to what extent patients using prescription antiobesity drugs (orlistat, sibutramine and rimonabant) used cardiovascular and antidiabetic drugs. Furthermore, EPOS-CC score may compare quality of care among different institutions. Cooperative ER/Pit-1 activation of the dormant PRL enhancer/promoter in pituitary progenitor cells requires the estrogen-dependent activation function-2 (AF-2) of ER, but is inhibited by one AF-2-interacting cofactor, RIP140.

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Intraoperative measurements on patients have confirmed these results. Constitutional predisposition and body structure for such patients has been defined. In this regard, aspirin also appears to be involved in an aspect of this signaling convergence. Two virulent strains were compared with one avirulent strain by 2-dimensional electrophoresis (2DE). A similar mechanism of action in the CNS could explain both the tremor and the decrease in brain 5-HIAA. beta 2-microglobulin levels were higher in both blood and BAL fluid of children. Twelve participants including nine parents whose infants were hospitalized in NICU, two nurses and one physician, all selected by purposive sampling method were interviewed by a what is the drug class of calcitriol female expert occupational therapist. A 1.8-fold rise was observed after the 9 baths which ultimately rose to 2.2 times the initial level after the conclusion of the treatment.

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