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Bicofen (Roxithromycin)

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Bicofen is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. It is a white crystalline powder. Bicofen is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring.

Other names for this medication:
Acevor, Aristomycin, Asmetic, Azuril, Bazuctril, Biaxsig, Bicofen, Biostatik, Cadithro, Claramid, Crolix, Delos, Dorolid, Elrox, Erybros, Floxid, Infectoroxit, Klomicina, Ladlid, Macrolid, Macrosil, Makrodex, Monobac, Nirox, Odonticina, Overal, Pedilid, Pedrox, Ramivan, Redotrin, Remora, Ritosin, Rokilide, Roksimin, Roksolit, Rolexit, Rolicyn, Rolid, Romac, Romyk, Rossitrol, Rotramin, Roxacine, Roxithromycin, Roxithromycine, Roxithromycinum, Roxitromicina, Rulid

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Also known as: Roxithromycin


Bicofen is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Bicofen is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring. It is also currently undergoing clinical trials for the treatment of male-pattern hair loss.

Bicofen is available under several brandnames. Bicofen is not available in the United States. Bicofen is available in Australia, Israel and New Zealand. Bicofen has also been tested to possess antimalarial activity.

Bicofen prevents bacteria from growing, by interfering with their protein synthesis. Bicofen binds to the subunit 50S of the bacterial ribosome, and thus inhibits the synthesis of peptides. Bicofen has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila.


Bicofen is typically prescribed for a period of 7 to 14 days and patients should take the medication for as long as it has been prescribed to prevent the infection from returning even if they become asymptomatic. Patients should not however, take doses larger than has been prescribed as this can result in an overdose. Overdosing requires immediate medical intervention and may present with symptoms which include abdominal pain, nausea, diarrhea, vomiting, and a general and prolonged feeling of illness.


Symptomatic treatment should be provided as required. There is no specific antidote.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Do not store in the bathroom. Keep in a tight, light-resistant container. Keep out of the reach of children.

Side effects

The most common side effects associated with Bicofen are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Bicofen if you are allergic to Generic Bicofen components. Try to be careful with Generic Bicofen if you're pregnant or you plan to have a baby, or you are a nursing mother. It can be dangerous to stop Generic Bicofen taking suddenly.

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The significant proportion of depressed patients that are resistant to monoaminergic drug therapy and the slow onset of therapeutic effects of the selective serotonin reuptake inhibitors (SSRIs)/serotonin/noradrenaline reuptake inhibitors (SNRIs) are two major reasons for the sustained search for new antidepressants. A detailed examination of the mode of binding of phorbol esters to protein kinase C led to a model of the phorbol binding site in the enzyme. Preparation and testing of a Haemophilus influenzae Type b/Hepatitis B surface antigen conjugate vaccine. Anandamide parallels delta 9-THC in its specific interaction with the cannabinoid receptor and in inhibition of adenylate cyclase. Prevalence of lipid and glycaemic abnormalities in hypertensive patients: a retrospective survey. In the final section, we consider the possible future of ambulatory care development in the light of government policy. Cerebral atrophy, apolipoprotein E varepsilon4, and rate of decline in everyday function among patients with amnestic mild cognitive impairment. The Fenna-Matthews-Olson protein revisited: a fully polarizable (TD)DFT/MM description. The authors report data from their own study designed to compare adult and neonatal ABR threshold using tonal stimuli. The effects of calcium antagonists on cyclic vasomotor activity are still present after short-term cozaar classification drug but not after long-term treatment withdrawal.

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Genetic characterization of 37 strains and CSF samples containing DNA of Haemophilus influenzae type b isolated in Moscow during 2007-2009. The in vitro effects of chylomicron remnant and very low density lipoprotein remnant on platelet aggregation in blood obtained from healthy persons. Killing kinetics and post-antibiotic effects were determined against C. Discounting paradigms quantify the ability to refrain from preference of immediate rewards, in favour of delayed, larger rewards. The comprehensive care of a pregnant patient in whom breast cancer is diagnosed presents a challenge to the biomedical and psychological competence of the medical team. In this situation surgical ventricular septal defect enlargement may be desirable but risks damage to the atrioventricular valve or conduction system. Our results show that the stone clearance rate is similar to that of non-MSK patients but there is a great reduction in the frequency of renal colic and UTI. 162 mental health consumers from community-based psychiatric rehabilitation centers were interviewed.

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