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Betacycline (Oxytetracycline)
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Betacycline

Betacycline is an antibiotic used to treat a wide variety of bacterial infections. The brand name drug Betacycline is no longer available in the U.S., but generic versions may still be available.

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Betacycline, Cotet, Dynoxytet, Ecomycin, Geomicina, Innolyre, Oxyteracin, Oxytetracycline, Tetracin

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Also known as: Oxytetracycline

Description

Betacycline is primarily bacteriostatic and is thought to exert its antimicrobial effect by the inhibition of protein synthesis. Betacycline is active against a wide range of gram-negative and gram-positive organisms.

The drugs in the Betacycline class have closely similar antimicrobial spectra, and cross resistance among them is common. Microorganisms may be considered susceptible if the M.I.C. (minimum inhibitory concentration) is not more than 4.0 mcg/ml and intermediate if the M.I.C. is 4.0 to 12.5 mcg/ml.

Susceptibility plate testing: A Betacycline disc may be used to determine microbial susceptibility to drugs in the Betacycline class. If the Kirby-Bauer method of disc susceptibility testing is used, a 30 mcg Betacycline disc should give a zone of at least 19 mm when tested against a Betacycline-susceptible bacterial strain.

Betacyclines are readily absorbed and are bound to plasma proteins in varying degree. They are concentrated by the liver in the bile, and excreted in the urine and feces at high concentrations and in a biologically active form.

Dosage

Take Betacycline by mouth with a full glass of water on an empty stomach at least 1 hour before or 2 hours after eating. Do not lie down for 30 minutes after taking Betacycline. Avoid taking milk, dairy products, calcium-enriched juices before and after consuming the drug. It is better to take Betacycline every day at the same time. Betacycline treats different types of bacterial infections and can be used both by adults and by children. Thus, each age has different instructions. For children above 8 years of age: the usual daily dose is 25–50 mg per kg of body weight divided into 4 equal doses. For Adults: the usual daily dose is 1–2 g divided in 4 equal doses, depending on the severity of the infection. For treatment of brucellosis, 500 mg oxytetracycline four times daily for 3 weeks should be accompanied by streptomycin, 1 gram intramuscularly twice daily the first week, and once daily the second week. For treatment of uncomplicated gonorrhea, when penicillin is contraindicated, tetracycline may be used for the treatment of both males and females in the following divided dosage schedule: 1.5 grams initially followed by 0.5 gram q.i.d. for a total of 9.0 grams. For treatment of syphilis, a total of 30–40 grams in equally divided doses over a period of 10–15 days should be given. Do not stop taking Betacycline suddenly. Therapy should be continued for at least 24–48 hours after symptoms and fever have subsided.

Overdose

If you overdose Generic Tetracycline and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Betacycline overdosage: retching, diarrhoea, nausea.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Betacycline are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not use Betacycline if you are allergic to Betacycline components. Do not use Betacycline if you take antacids containing aluminum, calcium, or magnesium impair absorption. Do not use Betacycline if you have liver problems, kidney disease. Do not take Betacycline if you're pregnant or you plan to have a baby, or you are breastfeeding. Betacycline is not to use in children under 8 years old. Do not take Betacycline if you suffer from porphyria. Use of Betacycline in children may cause permanent discoloring of the teeth. Do not drive, operate machinery or perform other possibly unsafe tasks until you know how you react to Betacycline. Try to be careful with sunbeams. Betacycline makes skin sensitive to sunlight. Protect skin from the sun. It's not recommended to use hormonal birth control as it may not work. To prevent pregnancy, use an extra form of birth control.

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Speech perception test results were obtained from a group of 40 pediatric cochlear implant users. The direction of the resulting integrated uni-directional MAE was measured. Bifunctional peptidylglcine alpha-amidating enzyme requires two copper atoms for maximum activity. The pathology informatics community now has the infrastructure needed to collaboratively and openly create, maintain and distribute the pathology informatics content worldwide (Wikipedia) and also the environment (the curriculum wiki) to draw upon its own resources to index and organize this content as a sustainable basic pathology informatics educational resource. Gemifloxacin showed a 2- to 16-fold greater activity than moxifloxacin or gatifloxacin against strains with two or more QRDR mutations, however, its potency did not translate to nonsusceptibility and gemifloxacin MIC values were either at or well above the CLSI nonsusceptible breakpoint concentration. Glycogen synthase in the rat tapeworm, Hymenolepis diminuta--II. Cerebral small vessel disease (SVD) is a major cause of age-related cognitive impairment and dementia.

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