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Barohexy (Trihexyphenidyl)
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Barohexy

Barohexy is used along with other medicines to help treat Parkinson’s disease. Parkinson’s disease is a brain disorder, which affects movement. The symptoms of Parkinson’s disease include trembling, rigid posture, slow movements and a shuffling unbalanced walk. Barohexy is also used after illnesses, which have after-effects like Parkinson’s disease.

Other names for this medication:
Barohexy, Doxogem, Lahexy, Mindol, Peradyl, Trihexane, Trihexonex, Trihexy, Trihexyphenidyl

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Also known as: Trihexyphenidyl

Description

Trihexyphenidyl is used alone or together with other medicines (e.g., levodopa) to treat Parkinson's disease. By improving muscle control and reducing stiffness, this medicine allows more normal movements of the body as the disease symptoms are reduced.

Trihexyphenidyl is also used to control severe muscle reactions and other side effects from certain medicines that are used to treat severe nausea or nervous, mental, or emotional conditions (e.g., haloperidol [Haldol®], loxapine [Loxitane®], prochlorperazine [Compazine®], promethazine [Phenergan®], thiothixene [Navane®]).

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain trihexyphenidyl. It may not be specific to Barohexy. Please read with care.

Take this medicine every day exactly as ordered by your doctor in order to improve your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

You may take this medicine before or after food, although it is usually taken with meals.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (elixir or tablets): For Parkinson's disease: Adults—At first, 1 milligram (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 15 mg per day, given in divided doses 3 or 4 times per day. Children—Use and dose must be determined by your doctor. For side effects caused by other medicines: Adults—5 to 15 milligrams (mg) per day, given in divided doses 3 or 4 times per day. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Barohexy and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

The most common side effects associated with Barohexy are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Simultaneous pharmacokinetic modeling of alkylresorcinols and their main metabolites indicates dual absorption mechanisms and enterohepatic elimination in humans. The aim of the study was to review our three year experience with translumbar insertion of dialysis catheters. The mean injurious force from the PMHS tests corresponded to a HIC(36 ms) value that would predict an elevated injury risk if it is assumed that fractures of the chin and skull are similarly correlated with HIC(36 ms). A different effect of thimerosal treatment was induction of renal and splenic vessel walls IC deposits. Molecular analysis of Streptococcus pyogenes strains isolated from Chinese children with pharyngitis. pX, which modulates the transcription machinery and/or modulation protein kinase signaling cascades, transactivates many host genes involved in cell proliferation, cytokine networks, acute immune response, and house-keeping functions.

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The long-term effects of traumatic early experiences on cortisol profiles are complex and indicate domain-specific effects, with normal recovery from physical stressors, but some heightened response to negative-affect social challenges. This recruitment is important for generating axial tension on the pericentromere and coordinating movement between pericentromeres from different chromosomes. Cirrhosis has multiple effects on the disposition of a wide range of antibacterial agents. Circulating AMH concentration was significantly lower among young Japanese women who had more-severe menstrual pain. Systolic luminal narrowing and morphologic characteristics of myocardial bridging of the mid-left anterior descending coronary artery by dual-source computed tomography. In the early luteal phase, levels of estrogen, progesterone, LH, total cholesterol, and HDL were significantly higher, compared with the early follicular phase. Therapeutic effectiveness of the laser use in dysfunctional uterine hemorrhage. The data obtained demonstrated that contact bedding was useful in controlling ammonia generation and that a raised floorwalk insert reduced significantly the aerosolization of bedding particles that could be ingested or inhaled by the rats. Orion: a web-based application designed to monitor resident and fellow performance on-call. The review begins with analysis of the emergence of combined agricultural-environmental systems, the environmental and social outcomes of recent agricultural revolutions, and analyses the challenges for food production this century as populations grow and consumption patterns change.

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To describe genetic analyses of the 2 most thoroughly studied, historically seminal multigenerational families with Alexander disease described prior to the identification of GFAP as the related gene, as well as 1 newly discovered family. When formulating guidelines, misconceptions should be identified and addressed. Data collected from extensive lymphadenectomy for all stages of gastric cancer have confirmed that some subsets of early gastric cancer are very low risk for nodal metastasis. Here we present evidence that incubation of oligodendrocyte progenitors, deprived of growth factor, with the acetylcholine analog carbachol significantly reduced cell death by apoptosis and blocked caspase-3 cleavage. Perforated Peptic Ulcer(PPU) though rare in pregnancy can occur and fasting can be a risk factor.

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Predictive maps for stochastic nonaffine stiffening and damage in fibrous networks. Apigenin widely inhibits cell proliferation of various lung cancer cell lines in a dose-dependent manner and the combination treatment of apigenin and antitumor drugs is very effective in human lung cancer cells, and Nrf2-ARE pathway may contribute to the mechanism. De novo detrusor instability in 3 cases was controlled with anticholinergics. The purpose of this study is to explore whether orthostatic plasma norepinephrine level could be an indicator of therapeutic effectiveness of metoprolol for POTS in children. Validation of fast diffusion kurtosis MRI for imaging acute ischemia in a rodent model of stroke. Temperature changes and their distribution induced by 13.56-MHz radiofrequency (RF) heating of agar phantom and porcine and rabbit liver were investigated. Reporting can be increased by adapting a number of standard techniques to the unique features of neonatal care and pathology. Increasing geographical inequalities in health in New Zealand, 1980-2001. It is accepted that this argument applies most clearly in cultures where there is no overt preference for one sex over another, but in those societies where this does not apply, it is equally unlikely that the concept of reproductive choice is valued. When using DWI, normalization of ADC values to muscle ADC may improve diagnostic performance.

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No significant effect on the tested parameters was found in 5 subjects. The interleukin-8 chemokine (IL-8) G-protein coupled receptor CXCR2 governs pro-inflammatory and pro-angiogenic responses in leukocytes and endothelial cells. In the histochemical study estradiol seemed to restore the acid phosphatase activity. Remote and rural maternity care includes a range of settings and models of care. We propose a type of lossless nonlinear polarizer, novel to our knowledge, a device that transforms any input state of polarization (SOP) of a signal beam into one and the same well-defined SOP toward the output, and perform this without any polarization-dependent losses. New insights into weaning from mechanical ventilation: left ventricular diastolic dysfunction is a key player.

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These results support the suggestion that under certain conditions, eosinophils may damage the heart, leading to endomyocardial disease, and they offer new approaches for the early diagnosis and treatment of endomyocardial disease both in temperate and tropical countries. The function of wisdom dimensions in ego-identity development among Chinese university students. The diagnostic and therapeutic management of acute and subacute forms. Postoperative complications affect hospital length of stay (LOS) as well as overall hospital cost. Clonal outbreak of Plasmodium falciparum infection in eastern Panama. The objective of this review was to evaluate the current status of human papillomavirus testing in predicting the presence of high-grade or invasive disease in the cervix in women with Papanicolaou smears reported as atypical squamous cells of undetermined significance (ASCUS price of xeloda 150 mg ) or low-grade squamous intraepithelial lesion. H2A.Z, a variant of H2A, is found at the promoters of inducible genes in both yeast and higher eukaryotes. Data were analysed using Chi-squared and logistic regression models.

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Apical membrane antigen 1 (AMA1) interacts with RON2 to form a protein complex that plays a key role in the invasion of host cells by malaria parasites. The present synthetic method can be applied to the facile synthesis of selenoxanthone which can be regarded as promising heterocyclic materials. We modified the surface of biodegradable nanoparticles loaded with antigen with different densities of the mAb to the DC lectin DEC-205 receptor and assessed changes in the cytokine response of DCs and T cells. In a pilot experiment, we generated a cDNA library from purified embryonic gonad and identified a novel germline-specific gene, RpL22-like. Uncomplicated peptic ulcers respond quite well to drug treatment, although recurrences are common and may require long-term maintenance therapy. This was shown to hold more promise than the SLT in discriminating between dementia and depression. The problem of nonsurgical versus surgical approach is discussed in the light of the relevant literature.

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