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Azoprine (Azathioprine)

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Azoprine is used with other medications to prevent transplant rejection (attack of the transplanted organ by the immune system) in people who received kidney transplants. Azoprine is in a class of medications called immunosuppressants.

Other names for this medication:
Aprin, Azathioprine, Azimune, Azoprine, Azoran, Immuzat, Imuzat, Thiazprine, Transimune, Zinothin, Zioprin, Zymurine

Similar Products:
Deltasone, Phenergan, Abhigra, Precose, Sinequan, Elavil, Imodium, Abilify, Coumadin, Lactone, Lobibeta, Balmusa, Vomitrac, Prebloc, Megatrim,

Also known as: Azathioprine


Azoprine weakens your body's immune system, to help keep it from "rejecting" a transplanted organ such as a kidney. Organ rejection happens when the immune system treats the new organ as an invader and attacks it.

Azoprine is used to prevent your body from rejecting a transplanted kidney. This medicine is also used to treat symptoms of rheumatoid arthritis.


Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using Azoprine.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

When given for kidney transplant, Azoprine is usually given right before or on the day of transplant. For rheumatoid arthritis, this medicine is taken on a daily basis.

It may take up to 8 weeks before your symptoms improve. Keep using Azoprine as directed and tell your doctor if your symptoms have not improved after 12 weeks of use.

Take with food if Azoprine upsets your stomach.

You may not be able to continue taking other arthritis medications together with Azoprine. Do not change your dose or dosing schedule without your doctor's advice.

Azoprine affects your immune system. You may get infections more easily, even serious or fatal infections. Your doctor will need to examine you on a regular basis.

Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

Detailed Azoprine dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Azoprine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Azoprine if you are allergic to Azoprine.

You should not use Azoprine to treat rheumatoid arthritis if you are pregnant. This medicine can harm an unborn baby. Use effective birth control to prevent pregnancy while using this medicine.

Azoprine may cause a rare type of lymphoma (cancer) of the liver, spleen, and bone marrow that can be fatal. This has occurred mainly in teenagers and young men with Crohn's disease or ulcerative colitis. However, anyone with an inflammatory autoimmune disorder may have a higher risk of lymphoma. Talk with your doctor about your own risk.

While taking Azoprine, you may have a higher risk of developing skin cancer. Ask your doctor about skin symptoms to watch for.

Tell your doctor if you have ever had:

kidney disease, or a kidney transplant (if you are using Azoprine for rheumatoid arthritis); any type of viral, bacterial, or fungal infection; liver disease; or chemotherapy with medications like cyclophosphamide, chlorambucil, melphalan, busulfan, and others.

You should not breast-feed while you are using Azoprine.

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