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Azold (Zolpidem)
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Azold

Azold is a drug that's used to treat insomnia. Insomnia is a sleep disorder that makes it difficult for you to go to sleep, stay asleep, or both. Azold is in a class of drugs called sedative-hypnotics. They work by slowing the activity in your brain, which allows for a state of sleep.

Other names for this medication:
Ambiz, Ambulax, Azold, Dactive, Getrest, Insom, Inzofresh, Isodem, Kayzole, Lipidem, Lopitas, Lypin, Nidra, Nitrest, Olpid, Restem, Sobrium, Stilnoct, Syzol, Zanlop, Zedem, Zodem, Zolax, Zolcent, Zoldem, Zolep, Zolfresh, Zolip, Zolit, Zolnex, Zolojet, Zolpel, Zolpiapt, Zolpid, Zolpidem, Zolpimist, Zolpirest, Zolpistar, Zolpitrac, Zolsoma, Zoltar, Zolway, Zomnia, Zopid

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Trileptal, Terramycin, Mysoline, Pepcid, Protonix, Dilantin, Wellbutrin, Metsig, Etophylate, Alzopam, Sigaprim, Sycyp, Alzine, Lotweet, Morecalm, Xifen, Yaxinbituo,

Also known as: Zolpidem

Description

Zolpidem is used to treat insomnia (trouble sleeping). It belongs to the group of medicines called central nervous system (CNS) depressants, which slows down the nervous system. Zolpidem will help you get to sleep faster and sleep throughout the night. In most cases, sleep medicines should only be used for short periods of time, such as 1 or 2 days, and for no longer than 1 or 2 weeks.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain zolpidem. It may not be specific to Azold CR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much is taken, it may become habit-forming (causing mental or physical dependence).

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Take zolpidem just before going to bed, when you are ready to go to sleep or when you are having trouble falling asleep. This medicine works very quickly to put you to sleep.

Swallow the extended-release tablet whole. Do not divide, crush, or chew it.

Do not take this medicine when your schedule does not permit you to get a full night's sleep (7 to 8 hours). If you must wake up before this, you may continue to feel drowsy and may experience memory problems, because the effects of the medicine have not had time to wear off.

Take this medicine on an empty stomach.

Do not take this medicine if you have drank alcohol the same evening or just before bedtime.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of insomnia: For oral dosage form (extended-release tablets): Adults—6.25 milligrams (mg) (for women) or 6.25 or 12.5 mg (for men) once a day at bedtime. Your doctor may increase your dose as needed. However, do not take more than 12.5 mg per day. Take only 1 dose a night as needed. Older adults—6.25 mg once a day at bedtime. Children—Use is not recommended. For oral dosage form (tablets): Adults—5 milligrams (mg) for women and 5 or 10 mg for men once a day at bedtime. Your doctor may increase your dose as needed. However, do not take more than 10 mg per day. Take only 1 dose a night as needed. Older adults—5 mg once a day at bedtime. Children—Use is not recommended.

Overdose

In postmarketing experience of overdose with Azold tartrate alone, or in combination with CNS-depressant agents, impairment of consciousness ranging from somnolence to coma, cardiovascular and/or respiratory compromise, and fatal outcomes have been reported.

General symptomatic and supportive measures should be used along with immediate gastric lavage where appropriate. Intravenous fluids should be administered as needed. Azold's sedative hypnotic effect was shown to be reduced by flumazenil and therefore may be useful; however, flumazenil administration may contribute to the appearance of neurological symptoms (convulsions). As in all cases of drug overdose, respiration, pulse, blood pressure, and other appropriate signs should be monitored and general supportive measures employed. Hypotension and CNS depression should be monitored and treated by appropriate medical intervention. Sedating drugs should be withheld following Azold overdosage, even if excitation occurs. The value of dialysis in the treatment of overdosage has not been determined, although hemodialysis studies in patients with renal failure receiving therapeutic doses have demonstrated that Azold is not dialyzable.

As with the management of all overdosage, the possibility of multiple drug ingestion should be considered. The physician may wish to consider contacting a poison control center for up-to-date information on the management of hypnotic drug product overdosage.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Azold CR dosage information

Side effects

The most common side effects associated with Azold are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid taking Azold during travel, such as to sleep on an airplane. You may be awakened before the effects of the medicine have worn off. Amnesia (forgetfulness) is more common if you do not get a full 7 to 8 hours of sleep after taking Azold.

Avoid driving or hazardous activity until you know how zolpidem will affect you. You may still feel sleepy the morning after taking Azold, and your reactions could be impaired. Wait until you are fully awake before you drive, operate machinery, pilot an airplane, or do anything that requires you to be awake and alert.

Do not take this medicine if you have consumed alcohol during the day or just before bed.

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In AR siRNA-transfected cells, tanshinone IIA did not cause cell cycle arrest and reduce cyclin D1, implying that AR is essential to induce G1 arrest by tanshinone IIA in LNCaP cells. This capability is expected to improve our understanding and management of retinal disease. Probe dependent anomalies in the solvation dynamics of coumarin dyes in dimethyl sulfoxide-glycerol binary solvent: confirming the local environments are different for coumarin dyes. In the present study, the effects of GDNF on postnatal ENS development were investigated using cultures of myenteric plexus from the small intestine of newborn albino rats of different developmental phases (P1, P7, P14). Clinical chemistry equipment: a computerized system for cost evaluation. The baseline survey was conducted in 1989 and the survival status of the respondents was ascertained during the subsequent 4 years. In this paper we make the original proposal of adopting a multiagent paradigm, called anthropic agency, to provide a powerful and flexible tool for combining partial models of heart rate regulation for adaptive cardiac pacing applications. Analysis of taste threshold distributions revealed significant variability, both within and between these two samples.

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Improving diagnostic accuracy of bacterial pharyngitis by near patient measurement of C-reactive protein (CRP). Synthesis, interaction with DNA and antiproliferative activities of two novel Cu(II) complexes with norcantharidin and benzimidazole derivatives. The relative activities of dextran, mannan and ovomucoid as agents inducing anaphylactoid responses in rats vary with the route of injection, mannan being the most active especially by the intradermal route. Moreover, we constructed a large comprehensive database of ligand binding pockets that will be searched against by a query. This is true for colorectal cancer in which mutations in signaling mediators predict resistance to anti-epidermal growth factor receptor (anti-EGFR) therapy. Here, a case of migratory bone marrow edema syndrome in a 47-year-old male patient, which was conservatively managed, is reported. communities of the Racial and Ethnic Adult Disparities in Immunization Initiative.

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Exciplex ensemble modulated by excitation mode in intramolecular charge-transfer dyad: effects of temperature, solvent polarity, and wavelength on photochemistry and photophysics of tethered naphthalene-dicyanoethene system. The peripheral artery questionnaire (PAQ) is a disease-specific health status measure of patients with peripheral artery disease (PAD). During thyroidectomy, the most common cause of UVFP, the superior laryngeal nerve (SLN), is also at risk of injury. The main feature of organ fibrosis is the excessive accumulation and deposit of extracellular matrix, thereby leading to organ dysfunction, loss of elasticity, and development of a rigid organ. Pulp reaction to the insertion of self-curing acrylic resin filling materials. Health care absorbs large private expenditures, sustained by households, remittances, charitable and solidarity funding, and constitutes a substantial portion of the country economy. Fracture risk in glucocorticoid-induced osteoporosis: comment on the article by Grossman et al. Participants found the study useful and believed that it would be of help in future critical appraisal. The rPLD1b mRNA increased within 6 h following dbcAMP treatment and maintained a high level up to 24 h. Experiments on both synthetic and real data highlight the benefit of considering fiber based statistical tests compared to the standard voxelwise strategy.

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