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Azithromycin

Azithromycin is a macrolide antibiotic used for various bacterial infections such as infections of the middle ear, throat, bronchus, sinuses, skin and soft tissue. It prevents bacterial growth. Azalides are a class of macrolide antibiotics which contain a nitrogen in the macrolide ring. This imparts different pharmacokinetic properties and is associated with greater stability of the molecule. One such Azalide is the antibiotic Azithromycin. It is also useful in treating pneumonia, typhoid, gonorrhoea, granuloma inguinale and chancroid.

Other names for this medication:
Amsati, Arzomicin, Azadose, Azenil, Azicine, Azimakrol, Azimex, Azinom, Azitral, Azitrim, Azitro, Azitrom, Azitropharma, Aztrin, Ericiclina, Maczith, Naxocina, Neblic, Neozith, Novozitron, Simpli, Tridosil, Tritab, Vinzam, Zaret, Zertalin, Zibac, Zimax, Zitrocin, Zitrofar, Zitroken, Zitrolid, Zitroneo

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Description

Azithromycin is a semi-synthetic macrolide antibiotic of the azalide class. Like other macrolide antibiotics, Azithromycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of the bacterial 70S ribosome. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the process of translation. Its effects may be bacteriostatic or bactericidal depending of the organism and the drug concentration. Its long half life, which enables once daily dosing and shorter administration durations, is a property distinct from other macrolides.

Azithromycin is the local analog (generic) of more famous drug Azithromycin that has the same active substance (ingredient) and in result the same therapeutic effect. The main difference is that Azithromycin is registered by a small local pharmaceutical company. The presence of the same active substance guarantees an identical pharmaceutical (therapeutic) effect on the body.

It is possible to buy Azithromycin only in the pharmacies of the country where it is produced. With us, you can buy its more famous analog Azithromycin, which is approved by the FDA and is sold worldwide. The same active substance guarantees the identity of the drugs and the identity of the pharmaceutical properties (they have only different names and packaging, in which they are sold).

Dosage

Use Azithromycin as directed by your doctor.

Take Azithromycin by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

Do not take an antacid that has aluminum or magnesium in it within 1 hour before or 2 hours after you take Azithromycin.

Azithromycin works best if it is taken at the same time each day.

To clear up your infection completely, use Azithromycin for the full course of treatment. Keep using it even if you feel better in a few days.

Ask your health care provider any questions you may have about how to use Azithromycin.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an Azithromycin overdose may include nausea, vomiting, diarrhea, and stomach discomfort.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not refrigerate or freeze the extended-release oral liquid. After water has been added to the powder, use the dose within 12 hours and throw away any unused liquid after your dose.

You may store the oral liquid at room temperature or in the refrigerator. Do not freeze the bottle. Do not keep the oral liquid for more than 10 days. Throw away any unused liquid after all doses are completed.

Side effects

The most common side effects associated with Azithromycin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Abnormal liver function, hepatitis, cholestatic jaundice, hepatic necrosis, and hepatic failure have been reported, some of which have resulted in death. Discontinue Azithromycin immediately if signs and symptoms of hepatitis occur.

The presence of other medical problems may affect the use of Azithromycin. Make sure you tell your doctor if you have any other medical problems, especially: allergy to any macrolide and ketolide antibiotic or liver disease with prior Azithromycin use or bacteremia (blood infection) or cystic fibrosis or infections, nosocomial or hospital-acquired or weak immune system or bradycardia (slow heartbeat) or hypokalemia (low potassium in the blood) or hypomagnesemia (low magnesium in the blood)

Not recommended in patients with these conditions: congestive heart failure or diarrhea or heart disease or Heart rhythm problems (e.g., prolonged QT interval), history of or Myasthenia gravis (severe muscle weakness).

Use with caution. May make these conditions worse: kidney disease, severe or liver disease. The effects may be increased because of slower removal of the medicine from the body.

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