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Azicine (Azithromycin)
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Azicine

Azicine is an antibiotic medication. It is commonly given to children for the treatment of a wide range of bacterial infections targeting the ear, eyes, nose, throat, lungs, skin, and gastrointestinal tract.

Other names for this medication:
Altezym, Amovin, Amsati, Atizor, Azadose, Azicip, Azifast, Azimakrol, Azimycin, Azithin, Azithrocine, Azithromycinum, Azitral, Azitrocin, Azyter, Bactrazol, Clearsing, Doyle, Faxin, Goldamycin, Inedol, Iramicina, Macrozit, Medimacrol, Novozithron, Oranex, Ordipha, Phagocin, Ribotrex, Ricilina, Simpli, Talcilina, Thiza, Trozocina, Zaret, Zentavion, Zertalin, Zetamax, Zibac, Zibramax, Zifin, Zinfect, Zitrocin, Zitrolid, Zocin, Zomax

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Also known as: Azithromycin

Description

Azicine (Azicine tablets and Azicine for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Azicine has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Azicine is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Azicine, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Azicine is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Azicine for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.

Dosage

A nurse or other trained health professional will give you this medicine. This medicine is given through a needle placed in one of your veins. This medicine is given slowly, so the needle will remain in place for about an hour.

Your doctor may give you a few doses of this medicine until your condition improves, and then you may be switched to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Detailed Azicine dosage information

Overdose

If you overdose Generic Azicine and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Azicine overdosage: discomfort feeling in stomach, diarrhea, retching, nausea.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not refrigerate or freeze the Zmax® extended-release oral suspension. After water has been added to the powder, use the dose within 12 hours and throw away any unused liquid after your dose.

You may store the Azicine® oral liquid at room temperature or in the refrigerator. Do not freeze the bottle. Do not keep the oral liquid for more than 10 days. Throw away any unused liquid after all doses are completed.

Detailed Azicine dosage information

Side effects

The most common side effects associated with Azicine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take antacids that contain aluminum or magnesium within 2 hours before or after you take Azicine. This includes Acid Gone, Aldroxicon, Alternagel, Di-Gel, Gaviscon, Gelusil, Genaton, Maalox, Maldroxal, Milk of Magnesia, Mintox, Mylagen, Mylanta, Pepcid Complete, Rolaids, Rulox, and others. These antacids can make Azicine less effective when taken at the same time.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking Azicine and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

Avoid exposure to sunlight or tanning beds. Azicine can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

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X-ray reflectivity (XR) and grazing incidence X-ray diffraction (GIXD) have been used to examine an oxyethylene-b-oxybutylene (E(23)B(8)) copolymer film at the air-water interface. Sequelae include adult respiratory distress syndrome, coagulopathy, shock, loss of fertility, and pituitary necrosis (Sheehan syndrome). Flapless surgery requires penetration of the alveolar mucosa and bone without reflection of mucoperiosteal flaps. Monomeric and dimeric anhydro sugars form during the thermolysis and are incorporated into the fructoglucan polymer. The CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiency.

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