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Axedol (Tramadol)
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Axedol

Axedol is a centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. Axedol is a centrally acting synthetic opioid analgesic and SNRI (serotonin/norepinephrine reuptake-inhibitor) that is structurally related to codeine and morphine.

Other names for this medication:
Accupain, Acema, Antram, Arrestadol, Atdol, Avdol, Axedol, Bludol, Dolocet, Dolodol, Dolomed, Dolstar, Drobit, Formador, Hyperdol, Jpdol, Mandol, Opidol, Opigesic, Oshdol, Paintrol, Ramax, Ramcet, Sedate, Tandam, Taramol, Traiz, Tramache, Tramacip, Tramaflam, Tramagesic, Tramared, Tramest, Trapidol, Tridol, Tromar, Typhon, Ultracon, Zamadol, Zytram

Similar Products:
Vantin, Duricef, Azulfidine, Antabuse, Lasix, Aldara, Eriacta, Provera, Levaquin, Xeloda, Plusgin, Isofloxx, Loratia, Cetrimin, Romet, Valcort,

Also known as: Tramadol

Description

Axedol ER is an pain medicine similar to an opioid. This medicine is used to treat moderate to severe pain.

The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.

Dosage

Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Axedol: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Axedol is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Axedol dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.

Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Axedol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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Global ischemia/reperfusion was adopted to induce myocardial ischemia/reperfusion injury (MIRI) in isolated rat heart. Experience-based agonistic behavior in female crickets, Gryllus bimaculatus. The average estimated blood loss was 562 mL, and three of four patients avoided transfusion. This clearly indicates that they are not involved in apoptosis signalling/progression. Characterization of RFB4-Pseudomonas exotoxin A immunotoxins targeted to CD22 on B-cell malignancies. In particular, tripolar mitoses were identified as surrogate markers of a near triploid DNA content. Oxytetracycline-induced nephrotoxicosis in dogs after intravenous administration for experimental bone labeling. Screening of family members of symptomatic probands has the potential to identify still asymptomatic carriers who may benefit from more appropriate thromboprophylaxis during high-risk situations for VTE. The Eph receptors and ephrins provide cell contact-dependent pathways that regulate axonal and dendritic development.

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Comparative activity of oral beta-lactam antibiotics at clinically achievable levels against Haemophilus influenzae serotype b. A ribozyme specific for Ki-ras mRNA carrying the activating mutation in codon 12 (GGU to GUU) was designed and shown to be stimulated by interaction with an RNA-binding protein NCp7 of HIV-1. Survey of the use of non-invasive positive pressure ventilation in U.K. The use of telemedicine to diagnose patients before they come to the ED may benefit the operation of your ED, as well as the emergency medicine system in general. Hypophophatasia is classified into six clinical forms namely, perinatal lethal, perinatal benign, infantile, childhood, adult and odontohypophosphatasia. These photoswitches offer the potential for rapidly and reversibly screening the vision restoration expected in an individual patient. Atorvastatin showed a number of cardiovascular benefits, however, the role and underlying molecular mechanisms of short-term atorvastatin-mediated protection remain unclear. In contrast, their influence on the proliferation of keratinocytes is discussed controversially.

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Hazardous alcohol use often co-occurs with psychological distress (e.g., depression and post-traumatic stress). The nucleotide sequence of sacbrood virus of the honey bee: an insect picorna-like virus. Congenital hypoplasia of the nasal wing can appear as a defect (congenital notch) or as a flattening and deficiency of the cartilagineous support. Fifteen other cases of rheumatism associated with this very special type of acne have been reported. Training induces plastic changes within the normal and injured brain. The aim of this study was to assess the efficacy and applicability of on-pump beating heart mitral valve replacement with Sorin Bicarbon prosthesis using prilosec otc vs generic omeprazole retrograde coronary sinus perfusion. The manufacture of clinical grade cellular products for adoptive immunotherapy requires ex vivo culture and expansion of human T cells. Genetic resistance and susceptibility to experimental Lyme arthritis have been linked with the production of interleukin-4 (IL-4) or gamma interferon (IFN-gamma), respectively.

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