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Axanthine (Allopurinol)

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Axanthine is a medicine used to treat and prevent gout. Gout happens when there is too much uric acid in your body. It forms into crystals that can appear around your joints and kidneys and cause pain. This medicine helps to keep uric acid levels low.

Other names for this medication:
Algoric, Allgoric, Allgout, Allopurinol, Alloric, Alopur, Aloric, Aloriv, Alpuric, Axanthine, Ciploric, Estinol, Lodiric, Mallor, Mecnol, Myloric, Purolic, Riloric, Satric, Seloric, Swiloric, Ureka, Uriclear, Urigon, Urinol, Uripure, Urxoall, Xoric, Zanupirol, Zeric, Zyloric, Zyprinol, Zyrinol

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Also known as: Allopurinol


Generic Axanthine is used for treating gout caused by excessive levels of uric acid in the blood (hyperuricemia). Hyperuricemia occurs when the body produces more uric acid than it can eliminate. The uric acid forms crystals in joints (gouty arthritis) and tissues, causing inflammation and pain. Elevated blood uric acid levels also can cause kidney disease and stones. Generic Axanthine prevents the production of uric acid by blocking the activity of the enzyme that converts purines to uric acid. Generic Axanthine prevents the production of uric acid by blocking the activity of the enzyme that converts purines to uric acid. Axanthine is also known as Allopurinol, Allohexal, Allosig, Progout, Zyloric, Puricos. Generic name of Generic Axanthine is Allopurinol. Brand names of Generic Axanthine are Axanthine, Aloprim.


Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

You may take this medicine after meals to avoid stomach upset.

Take this medicine with plenty of liquids to help prevent kidney stones. Check with your doctor about the amount of liquid you should drink each day. You should also increase your fiber intake.

You may need to lessen your intake of animal protein, sodium, refined sugars, or foods rich in oxalate and calcium, especially if you have kidney stones that keep coming back.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets): For gout: Adults—At first, 100 to 300 milligrams (mg) per day, taken once a day or in divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 800 mg per day. Children—Use and dose must be determined by your doctor. For high uric acid levels caused by cancer medicines: Adults and children 11 years of age and older—600 to 800 milligrams (mg) per day, taken in divided doses for 2 to 3 days. Children 6 to 10 years of age—300 mg per day, taken once a day for 2 to 3 days. Children younger than 6 years of age—150 mg per day, taken once a day for 2 to 3 days. For kidney stones: Adults—200 to 300 milligrams (mg) per day, taken once a day or in divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 800 mg per day. Children—Use and dose must be determined by your doctor.


If you overdose Generic Axanthine and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from light and moisture. Do not store in the bathroom. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Axanthine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of allopurinol in children with high uric acid levels caused by cancer.

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NADPH oxidase inhibitors and superoxide scavengers significantly decreased Ang II-induced ET-1 mRNA and peptide expression, superoxide production as well as collagen expression. Osteoporosis is caused by excessive bone resorption (by osteoclasts) over bone formation (by osteoblasts). Adherence is the degree to which patients comply with their caregivers prescribed treatments. Effects of social demands on generalized imitation learning in retarded children. The third example of a pathogenic immune reaction is virus-induced immune complex diseases (infections with FeLV, FIPV and CAV-1). Effects of oral and transvaginal ethinyl estradiol on hemostatic factors and hepatic proteins in a randomized, crossover study. Mammalian cells expressing Escherichia coli O6-alkylguanine-DNA alkyltransferases are hypersensitive to dibromoalkanes. A crevicular washing method for investigating immune components of crevicular fluid in man. This review summarizes what is known about the functional consequences of the interaction of C1q with cells, and describes initial investigations of the biochemical mechanisms/signal transduction pathways involved in these C1q-induced responses. A thin film of SiO2 with thickness of 200 nm (used as sacrificial layer) was coated by physical evaporation deposition (PVD) first.


Although several studies have outlined the need for and benefits of diversity in academia, the number of underrepresented minority (URM) faculty in academic health centers remains low, and minority faculty are primarily concentrated at the rank of assistant professor. This review article will briefly discuss the features and potential application of recent advances in ligand-based drug design, with emphasis on a detailed description of a novel 3D QSAR method based on the conformationally sample pharmacophore (CSP) approach (denoted CSP-SAR). Dose responses for an endothelium-dependent vasodilator, acetylcholine (ACh, via endothelium-dependent nitric oxide), and an endothelium-independent vasodilator, nitroglycerin, were determined. The objective of this study is to develop a simple assay for identifying hypercholesterolemia, and assessing the impact of therapeutic treatments. Both had successful treatment after CVC removal and combination drug therapy. Diabetes information systems linking multiple data sources have been described. Successful pregnancy in a patient with heart failure secondary to aortic and mitral regurgitation. Anatomy of the common trunk of the middle and left hepatic veins: application to liver transplantation.

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Clinicopathological implications of parathyroid hormone-related protein in human colorectal tumours. The enzyme systems in cellulolytic bacteria have been investigated by sequencing and bioinformatic analysis of genomes from plant biomass degrading microorganisms with valuable insights into the variety of the involved enzymes. The study findings will be published in peer-reviewed journals and presented at national and international conferences. Pseudomonas pseudoalcaligenes KF707 possesses a chromosomally encoded bph gene cluster responsible for the catabolism of biphenyl and polychlorinated biphenyls. In Northern and Central Europe, where there are no olive trees, there are two commonly occurring genera of the Oleaceae family, namely Fraxinus and Ligustrum, but these have a low frequency of allergic sensitization. We report the experimental results and theoretical analysis of broadband detection of terahertz (THz) waves via electric-field-induced second-harmonic generation in laser-induced air plasma with ultrashort laser pulses. The same instrument was used by the same operator for all scans. To identify cis-acting elements and trans-acting factors involved in the expression of human IRBP gene. (Apricot) extracts ameliorates TNBS-induced ulcerative colitis in rats.

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The aim of this study was to investigate the significance of IgG subclasses and MBL for susceptibility to infection in association with IgA deficiency. Recent studies have revealed two methods to increase binding affinity for FcgammaRIIIa and enhance ADCC more efficiently for antibodies: (i) fucose removal from antibody N-linked complex oligosaccharides and (ii) amino acid mutations in the antibody Fc region. Advancement in stationary phase for peptide separation helps in protein identification: application to atheroma plaque proteomics using nano-chip liquid chromatography and mass spectrometry. Transverse osteotomies on 65 cadaver femora were fixed with two or three screws of two types: one with a shank diameter of 6 mm and thread diameter of 8 mm, and a prototype screw with equal shank and thread diameter of 7 mm. In conclusion, combining the in vitro myelination assay with lentiviral infected OPCs provides a strategic tool for the analysis of molecular mechanisms involved in myelination.

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MicroRNA-145 contributes to enhancing radiosensitivity of cervical cancer cells. Estrogen supplementation was needed to maintain the features of uterine leiomyoma in xenografted tissues. Myocardial fibrosis puts the patient at risk for systolic or diastolic heart failure and dysrhythmias. Another approach described uses Wiener-Volterra kernel technique to obtain a satisfactory estimation and causality test among EEG recordings. After egg-yolk-induced reactive lymph-node hyperplasia, the enlarged nodes were well demonstrated by MRI. These may include one or more of those proteins identified as having an affinity for osteoprogenitor cells that are either exclusively present or up- or downregulated in the serum and CSF of brain-injured patients. Specifically, the proposed approach is based on large margin structured output learning and the visual consistency is integrated with the click features through a hypergraph regularizer term.

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The potential of capillary electrophoresis for fast analyses of nanoparticles, their conjugates with antibodies, and immunocomplexes with targeted antigens is demonstrated on examples. Fatal intracerebral haemorrhage secondary to Aspergillus arteritis following aneurysm clipping. Bromodeoxyuridine (BrdUrd) labelled and unlabelled mitotic cells, respectively, can be discriminated from interphase cells using a new method, based on immunocytochemical staining of BrdUrd and flow cytometric four-parameter analysis of DNA content, BrdUrd incorporation, and forward and orthogonal light scatter. To evaluate the long-term endothelial cell loss after implantation of Worst-Fechner and Baikoff ZB5M anterior chamber intraocular lenses. In conclusion, ATRA has an inhibitory effect on the cell growth of MiaPaCa-2, and its tumor suppressive effect is by means of cell cycle arrest and apoptosis induction. Vascular resection was performed in 26 patients, with a total of 31 resected vessels (3 of grade 0, 5 of grade I, 8 of grade II, 15 of grade III).

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Proceedings: An amplitude discriminator for use in research and teaching. We describe a protocol for systematically determining the appropriate level of modeling to fit a SAXS data set based on goodness of fit and whether the addition of parameters improves it. Previously agreed upon counting criteria as well as standardized FISH hybridization protocols may decrease this variability. In two postoperative groups of patients with low and high blood loss from chest drainage, we determined, in addition to free plasma hemoglobin, the following: factor XII, kallikrein-like activity, thrombin-antithrombin III complex, tissue-plasminogen and d-dimers. The genetic basis of intrinsic and extrinsic post-zygotic reproductive isolation jointly promoting speciation in the lake whitefish species complex (Coregonus clupeaformis).

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