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Avodart

Avodart is a medication primarily used to treat the symptoms of an enlarged prostate. A few months may be required before benefits occur. It is also used for scalp hair loss in men and as a part of hormone therapy in transgender women. It is taken orally

Other names for this medication:
Alfuprost, Alfusin, Duagen, Duprost, Durize, Dutalfa, Dutas, Dutasteride, Dutride, Flodart, Jalyn, Jyotam, Sterdu, Tamcontin, Tamdura, Urifine, Urimax, Uritin, Veltam, Veltride

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Also known as: Dutasteride

Description

Avodart is produced by GlaxoSmithKline. Benign prostatic hyperplasia (benign prostatic hypertrophy or benign prostatic adenoma) is an overgrowth of cells of the prostate due to the aging process and hormonal changes. The enlarged prostate squeezes the urethra, obstructs the urine flow and makes it difficult for the patient to void his bladder. BPH is characterized by frequent urination, urgency to urinate (compelling need to void that cannot be deferred), involuntary urination, urge incontinence, urinary hesitancy (a delay between trying to urinate and the flow actually beginning), intermittency (not continuous), involuntary interruption of voiding, weak urinary stream etc. Avodart soft gelatin capsules (softgels) contain the active ingredient Dutasteride which aim is to inhibit the action of both isoforms (type I and type II) of the enzyme 5α-reductase, that converts the male sex hormone testosterone to dihydrotestosterone (DHT). DHT is another male sex hormone (androgen) that causes the growth of prostate gland. This helps to relieve such symptoms of BPH as starting to urinate, weak stream, and the need to urinate frequently or urgently (including during the middle of the night). Taking Avodart may also reduce the need for surgery to treat BPH. Avodart can be used for the treatment of male pattern baldness (MPB) or androgenetic alopecia (AGA) off-label. DHT, which is also found in hair follicles, is the androgen responsible for hair loss, as it causes hair follicles to miniaturize and atrophy. Avodart softgels reverse hair loss process as it blocks the build-up of DHT in the hair follicles of the scalp, allowing the hair to grow normally.

Dosage

Take it orally with or without food. Do not crush or chew it. Take Generic Avodart at the same time once a day. This medicine is only for men. If you want to achieve most effective results do not stop taking Generic Avodart suddenly.

Overdose

If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Avodart are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Using Avodart may increase your risk of developing prostate cancer. Your doctor will perform tests to make sure you do not have other conditions that would prevent you from safely using Avodart.

Before taking Avodart, tell your doctor if you have ever had an allergic reaction to this medication, or to a similar medicine called finasteride (Propecia, Proscar).

Avodart should never be taken by a woman or a child. Dutasteride can be absorbed through the skin, and women or children should not be permitted to handle Avodart capsules. Although this medicine is not for use by women, this medication can cause birth defects if a woman is exposed to it during pregnancy. Avodart capsules should not be handled by a woman who is pregnant or who may become pregnant. If a woman accidentally comes into contact with this medication from a leaking capsule, wash the area with soap and water right away.

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ADAM10 and ADAM17 have opposite roles during sprouting angiogenesis. Increased plasma S-adenosylhomocysteine-accelerated atherosclerosis is associated with epigenetic regulation of endoplasmic reticulum stress in apoE-/- mice. Self emulsifying drug delivery system (SEDDS) for phytoconstituents: a review. However, in vivo, similar observations have not been easily made so far. Artemisia extracts have been used as remedies for a variety of maladies related to metabolic and gastrointestinal control. Twenty to 30 mg BU/kg produced severe but in most cases reversible myelotoxicity.

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Forty-three patients with biopsy-proven primary lung malignancy with pathological mediastinal nodal staging and unenhanced CT of the thorax were studied retrospectively. Tuberoinfundibular dopamine tonically inhibits PRL expression and secretion from the pituitary gland by the activation of dopamine D2 receptors (D2R) localized on lactotrophs. This article introduces a novel tai chi intervention and provides quantitative and qualitative data from a randomized clinical trial indicating its effects on psychosocial variables in individuals living with various stages of HIV disease. Many clinical trials have been carried out with many more in progress. Clinical governance places for legal duty for quality on Trust chief executives. Report on the thirteenth Congress of the International Society of the History of Medicine. officinalis aqueous extracts (infusions and decoctions) only showed presence of tannins, saponins, flavanoids, Terpenoids and phenols.

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Risk factors and management of post-intubation tracheal stenosis. Meconium/stool specimens were obtained on days 1, 3, 5 and 7 from 38 very low-birth-weight infants in a level III neonatal intensive care unit. We show how the BACs provide molecular links for understanding human genomic duplications, meiosis, and evolution, as well as reagents for conducting genome-wide prenatal diagnosis at the molecular level and for detecting gene candidates associated with novel cancer breakpoints. Any such observed changes should be investigated through further data analysis and/or mosquito trapping and testing in order to assess validity. Higher aspirin doses may have clinical utility in particular settings, but this requires further study. Minimum, maximum, and mean ADC values (ADCMIN , ADCMAX , and ADCMEAN , respectively) were measured from ADC maps obtained for the two b-values for each subject.

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Neonatal mortality in a referral prevacid dose infant hospital in Cameroon over a seven year period: trends, associated factors and causes. Lethality is apparently attributable to asphyxia and is dependent on the level of CVF administered: eg, 100 micrograms CVF was not lethal in 4 animals given SCPN inhibitor, although signs of respiratory distress were observed. Functional MR imaging, similar to positron-emission tomography, shows the regions in which cerebral blood flow changes as neurons are active in the performance of cognitive tasks. The clinical symptoms are often non-specific and the diagnosis is often delayed. The potential dangers of complementary therapy use in a patient with cancer. Computed tomography is still preferred to MRI for imaging the pancreas. There are strong indications that maternal serum hyperrelaxinemia correlates with an increased risk of preterm birth. A yeast strain defective in oleic acid utilization has a mutation in the RML2 gene. injection the tissue distribution of liposomal Dxn is drastically changed.

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A stream of new data from randomized clinical trials has recently prompted the release of a focused update of the PCI guidelines, endorsing new recommendations on the use of antiplatelet drugs and parenteral anticoagulants. acquisition phase, social approach (SA), and hippocampal mRNA expression were compared at P65 in 4 male adult offspring groups: formerly iron deficient (FID), FID with choline supplementation (FID-C), IS, and IS with choline supplementation. Protein kinase Cdelta mediates neurogenic but not mitogenic activation of mitogen-activated protein kinase in neuronal cells. Comparison of three plate system for lateral malleolar fixation. Western blot analysis showed that phospho-ser727-STAT3 significantly increased from 8 to 48 h after nonlethal ischemia, while it increased only for 1h after lethal ischemia and returned to the baseline within 24h. Ileorectal anastomosis (IRA) is a possible surgical treatment for hyperacute and drug-unresponsive forms of ulcerative colitis (UC). The strains were grown under filamentous and non-filamentous conditions. The cells were chiefly eosinophilic with a regular oval grooved nucleus and a small inconspicuous nucleolus. Complete data about residual drug in the inserts and plasma concentrations of misoprostol acid were gathered for 27 and 25 patients, respectively. All 10 investigated mushroom species inhibited the reproduction of influenza virus strain A/FM/1/47 (H1N1) in MDCK cells reducing the infectious titer by 2.0-6.0 lg ID50.

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