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Ativan (Lorazepam)

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Ativan is used to treat anxiety. Ativan belongs to a class of drugs known as benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. This drug works by enhancing the effects of a certain natural chemical in the body (GABA). Ativan may also be used to treat: Symptoms from Alcohol Withdrawal, Mania associated with Bipolar Disorder, Adjunct Treatment, Muscle Spasm, Chronic Trouble Sleeping, A Feeling of Restlessness with Inability to Sit Still, Nausea and Vomiting caused by Cancer Drugs, Prevent Nausea and Vomiting from Cancer Chemotherapy, Psychosis caused by Sudden Alcohol Withdrawal.

Other names for this medication:
Almazine, Anxilor, Anxionil, Anxipose, Atipam, Biokalm, Biolar, Calmese, Dulozep, Larosh, Lopam, Lopez, Loracalm, Lorakar, Loralite, Lorazam, Lorazepam, Lorazine, Loricon, Loripam, Lorivan, Lorpam, Lorvin, Lotweet, Nexlor, Norpose, Olraz, Trapex, Urpam, Zelor, Zepatrac, Zepnap

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Desyrel, Danocrine, Microzide, Nolvadex, Ovral, Levaquin, Rogaine, Valaplex, Valcap, Unasera, Hyphoral, Kiraza, Clopin,

Also known as: Lorazepam


Ativan belongs to a class of medications called benzodiazepines. These medications work by boosting the activity of gamma-aminobutyric acid (GABA) within your body.

GABA is a neurotransmitter that transmits messages between cells in different parts of your body. Increasing GABA in the body results in a tranquilizing effect that reduces feelings of stress and anxiety.

How long does it take to work?

Benzodiazepines such as Ativan are categorized based on how fast they work. Ativan is classified as having a rapid to intermediate onset (start) of action. It begins to work right away after it’s taken, but its peak effect occurs within 1 to 1.5 hours.


Take Ativan exactly as it was prescribed for you. Follow all directions on your prescription label. Never use Ativan in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in treating your symptoms.

Lorazepam may be habit-forming. Never share Ativan with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

Misuse of habit-forming medicine can cause addiction, overdose, or death. Selling or giving away Ativan is against the law. Ativan should be used for only a short time. Do not take this medicine for longer than your doctor recommends.

Do not stop using Ativan suddenly or you could have unpleasant withdrawal symptoms, including a seizure (convulsions). Ask your doctor how to safely stop using this medicine. Call your doctor if this medicine seems to stop working as well in treating your anxiety symptoms.


In a medical setting an overdose would be treated quickly.


Store Ativan at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Ativan is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Ativan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Ativan should be avoided in people with:

Sleep apnea – Sleep apnea may be worsened by Ativan's central nervous system depressant effects. It may further reduce the patient's ability to protect his or her airway during sleep.

Myasthenia gravis – This condition is characterized by muscle weakness, so a muscle relaxant such as Ativan may exacerbate symptoms.

Pregnancy and breast feeding – Ativan belongs to the Food and Drug Administration (FDA) pregnancy category D, which means it is likely to cause harm to the developing baby, if taken during the first trimester of pregnancy. Evidence is inconclusive whether Ativan, if taken early in pregnancy, results in reduced intelligence, neurodevelopmental problems, physical malformations in cardiac or facial structure, or other malformations in some newborns. Ativan given to pregnant women antenatally may cause floppy infant syndrome in the neonate, or respiratory depression necessitating ventilation. Regular Ativan use during late pregnancy (the third trimester), carries a definite risk of benzodiazepine withdrawal syndrome in the neonate. Neonatal benzodiazepine withdrawal may include hypotonia, reluctance to suck, apneic spells, cyanosis, and impaired metabolic responses to cold stress. Symptoms of floppy infant syndrome and the neonatal benzodiazepine withdrawal syndrome have been reported to persist from hours to months after birth. Ativan may also inhibit fetal liver bilirubin glucuronidation, leading to neonatal jaundice. Ativan is present in breast milk, so caution must be exercised about breast feeding.

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