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Asoprol (Metoprolol)

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Asoprol is a type of medicine called a beta blocker. Like other beta blockers, Asoprol works by changing the way your body responds to some nerve impulses, especially in the heart. It slows down your heart rate and makes it easier for your heart to pump blood around your body.

Other names for this medication:
Actiblok, Actocard, Asoprol, Betaloc, Betaone, Blumeta, Cadmet, Dutoprol, Intramet, Macsart, Mepol, Metapro, Metin, Metocare, Metofin, Metolar, Metolex, Metomac, Metoprolol, Metozest, Metpure, Metscore, Metzok, Nexovas, Powermet, Sitelol, Supermet, Telidin, Teliprolol, Toprol, Translol, Vasomet, Vinicor, Vivalol

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Also known as: Metoprolol


Hydrochlorothiazide is a thiazide diuretic (water pill). Metoprolol is a beta-blocker.

Asoprol HCT is a combination medicine used to treat high blood pressure (hypertension).


This section provides information on the proper use of a number of products that contain metoprolol. It may not be specific to Asoprol. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Your dose may need to be changed several times in order to find out what works best for you.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of food you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should first check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many patients feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, strokes, or kidney disease.

Swallow the extended-release capsule and tablet whole. Do not crush, break, or chew them.

If you cannot swallow the extended-release capsule:

You may open it and sprinkle the contents over a small amount (teaspoonful) of soft food (including applesauce, pudding, or yogurt). Swallow the mixture within 60 minutes. Do not store for later use. You may also use a nasogastric tube to give the medicine. Mix the contents of the opened capsule with water into a syringe. Gently shake the mixture for about 10 seconds, then flush it through the tube. Rinse the tube with water until all of the medicine is washed out.

Take the tablet or extended-release tablet with a meal or just after you eat. You may break the extended-release tablet into two pieces, but swallow the two pieces whole and do not crush or chew them.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For acute heart attack or heart failure: For oral dosage form (extended-release capsules): Adults—At first, 25 milligrams (mg) once a day for 2 weeks. Your doctor may adjust your dose as needed. However, the dose is usually not more than 200 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 25 milligrams (mg) once a day for 2 weeks. In patients with severe heart failure, the starting dose is 12.5 mg once a day. Your doctor may adjust your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 50 milligrams (mg) every 6 hours for 2 days. Then, 100 mg 2 times a day. The medicine will be started in the hospital. Children—Use and dose must be determined by your doctor. For chest pain: For oral dosage form (extended-release capsules): Adults—At first, 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 100 milligrams (mg) per day, given in two divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children—Use and dose must be determined by your doctor. For high blood pressure: For oral dosage form (extended-release capsules): Adults—At first, 25 to 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children 6 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 1 milligram (mg) per kilogram (kg) of body weight once a day. The first dose should not be more than 50 mg once a day. Your doctor may adjust your dose as needed. Children younger than 6 years of age—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 25 to 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children 6 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 1 milligram (mg) per kilogram (kg) of body weight per day, given as a single dose. The first dose should not be more than 50 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 100 milligrams (mg) per day, given as a single dose or in divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 450 mg per day. Children—Use and dose must be determined by your doctor. .


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include fast or slow heart rate, trouble breathing, or fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Asoprol dosage information

Side effects

The most common side effects associated with Asoprol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


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Development and phonetic differentiation of speech movement patterns. A screening of fungal and microbial strains allowed to select the best microorganisms to produce in high yields some of the human metabolites of two benzodiazepine drugs, diazepam and clonazepam, in order to study new pharmacological activities and for chemical standard proposes. Unlike in Crimp Cap vials, in Exetainers no nitrous oxide loss following low pressure storage was detectable. This eliminates the need for serial dilutions in a separate titration and reduces the number of necessary reactions. These factors include physicochemical and biological ones, with the emphasis on the latter, including membrane permeation, enzymatic metabolism, and excretion by efflux transporters. The pd values were similar whether the ileostomy had been recently or long established. However, as reasonable as this sounds, there remains no conclusive evidence of such a molecular machinery in insects.

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To review the phenomenon and implications of temporal bone and craniofacial bone staining in the context of prolonged exposure to tetracycline antibiotic. This observation was confirmed by the relationship between AST behaviour and quantitative alcohol intake. Galanin-like peptides exert potent vasoactive functions in vivo. There were 40 men and 10 women with an average age of 44 years (range, 19-76 years). Maternal use of acetaminophen, ibuprofen, and acetylsalicylic acid during pregnancy and risk of cryptorchidism. This paper is a case report describing the successful microvascular replantation of a completely degloved thumb, the result of an avulsion injury caused by a drill.

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GC receptor was first shown to be a potent activator of transcription, but recently, GC receptor has also been shown to repress expression of various of genes through interaction with other transcriptional factors. The identification of heat shock protein genes in goldfish (Carassius auratus) and their expression in a complex environment in Gaobeidian Lake, Beijing, China. Compared to these large-scale changes in morphology, more subtle changes were induced by structural changes in the acyl chain of 24:1(Delta15)GalCer. Restoration to normal structure can be accomplished mainly by plication. Role of chloride and inhibitory action of inorganic nitrate on gonadotropin-stimulated steroidogenesis in mouse Leydig tumor cells. We describe the clinical and imaging features of a group of rare lymphoepitheliomas related to the palate.

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115 consecutive patients with inoperable malignant biliary obstruction underwent endoscopic placement of 10 Fr straight, plastic biliary stents, Amsterdam-type. Patients with dyspepsia, normal upper gastrointestinal endoscopy and no psychological comorbidity according to the 12-item General Health Questionnaire underwent duodenal biopsy sampling. The actual states and aspects of psychiatric emergency services in Tokyo, Chiba, and Kanagawa areas. The success of clinical BAL application systems is, however, largely dependent on the functionality and stability of hepatocytes. Gel-shift experiments performed with whole cell extract of those cells, containing approximately 700 fmol AR/mg protein, and labeled AR-binding GRE (glucocorticoid responsive element) showed that R1881 induced the formation of a protein-GRE complex. However, there is a need for further research into the relationship between visual impairment and chronic medical conditions in the elderly. However, exposure of capsids to increasing temperatures or low pH led to its progressive accessibility without particle disassembly. The involvement of T cells in IgE-mediated enhancement of the Ab response was studied in several ways: nude mice were resistant to the effect of IgE and a dramatic effect on the induction of immunologic memory was seen, both by in situ secondary immunizations and in adoptive transfer systems. Rabbits were injected bilaterally with a 0.5 mL ( approximately 1.33 x 10(14) PCN) volume.

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This suggests that DNA phosphates may be sandwiched between lysine and arginine groups of H1 histone when this molecule binds to chromatin, constituting a relevant parameter for the reciprocal stabilization of the protein and of the chromatin higher order structures. Hyaline membrane disease: diagnosis, radiologic surveillance, treatment and complications. Detection of multiple drug-resistance-associated pol mutations in cervicovaginal secretions from women largely treated with antiretroviral agents. We believe that increased awareness and sophisticated echocardiographic techniques should lead to an increased recognition of accessory mitral tissue causing subaortic stenosis. The study evaluated responses of human primary airway epithelial cells to diesel exhaust (DE). Mathematical correlation between villus height and the nutritional state in Sprague-Dawley rats. With the increasing use of computers to store patient data and to use these data as an electronic patient record to support the direct patient care these data now play an essential role in the care process. The recording of blue cone (S-cone) responses as described by Gouras and MacKay was slightly modified and incorporated into our routine ganzfeld electroretinogram protocol. Automatic detection and analysis of intracardiac electrograms for electrophysiology studies by digital signal processing chip implementation. Alteration of iron homeostasis following chronic exposure to manganese in rats.

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Malignant neoplastic epithelial cells from primary breast cancers and luminal and myoepithelial cells isolated from normal human breast tissue were isolated by immunomagnetic separation methods. These are choline-like molecules, the latter of which is apparently formed by a prebiotic methylation process. The detection of laser-induced structural change of MnO2 using in situ Raman spectroscopy combined with self-modeling curve resolution technique. The maximum extent of irreversible binding was at 4 hr for the R-ketoprofen conjugate, but was later for the S-form. all patients were admitted for the need of mechanical ventilation. Across all four memory response types, an increase in confidence at recognition was associated with bilateral activation in the anterior and posterior cingulate cortex along with medial temporal regions. This mouse model offers new insights into the pathophysiology of LPI and into mechanisms linking CAA metabolic pathways and growth control. Electrocardiographic findings in 24 patients with myasthenia gravis. This discussion reviews the recent literature as it pertains to the management of coincident cataract and glaucoma.

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Carbon nanotube-based separation columns for microchip electrochromatography. Fluorescein isothiocyanate labelled bovine serum albumin (FITC-BSA) as a model protein drug: opportunities and drawbacks. Under these conditions, resolution of the various sialoforms from the iron-saturated Tf was possible and the glycoforms were found to migrate differently than their iron-depleted counterparts. In Australia, the Act on the Rights of the Terminally Ill of 1995 legalized the institution of assisted suicide, which is not identical to active euthanasia. In T cells, MIF-mediated activation of the JNK pathway led to upregulated gene expression of the inflammatory chemokine CXCL8. Assessment of functional activity of cold-stored kidney transplant by proton magnetic resonance spectroscopy. The aAPCs support ex vivo growth and long-term expansion of functional human CD8 T cells without requiring the addition of exogenous cytokines, in contrast to the use of natural APCs. Of six patients treated with lamotrigine, five have improved substantially, but only one is in sustained complete remission. hominis have almost the same sexual risk behaviour as women with classic sexually transmitted diseases. Additionally, the lack of influence of EMD 57445, administered po, on the dopamine D1 and D2 receptor binding in the striatal membranes was observed in these studies.

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A delineation of contemporary needs, a modern view of the elements of cancer induction, and bactrim ds 100 mg an examination of new assays and technologies may provide a framework for integrating new approaches into current schemes for evaluating the potential genetic and carcinogenic risk of environmental chemicals. While the venom components of cone snails have been intensively characterized, the mechanism of venom translocation and loading prior to and during injection remains elusive. In all other cases of high energy trauma, spinal trauma with neurological deficit or incomplete or difficult standard radiographic evaluation, CT will be indicated for osseous injuries while MRI will provide optimal evaluation of soft tissues. The aim of the present study is to establish a novel nude mouse model with xenografted human bladder cancer. The most frequent toxicities were edema and fatigue, with dose-limiting fatigue and dyspnea. Rheumatologic manifestations of chronic myelomonocytic leukemia. The benefits and risks of use of these agents versus conventional treatment need to be considered on a case-by-case basis by the surgeon.

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Are there dosage of xanax bar differences between the secretion characteristics of NGF and BDNF?. Etiology of late-onset tibia vara: is varus alignment a prerequisite?. A lensless interferometric camera that captures planes of mutual intensity data is described and used to reconstruct an incoherently illuminated visible object in three dimensions. An atypical presentation of fibrous dysplasia with a very large cystic component is described. These genes encode the alternative sigma factor AlgT (sigma(22)), its anti-sigma factors MucA and MucB, MucC, a protein with a controversial function that is absent in P. Value of thermography in the examination of ischemias of the hands. The echocardiograms of two patients with sclerodermatous cardiac disease are described. Combining our results with findings made previously in other Hymenopteran species, we discuss possible functions and some of the ultimate factors influencing the evolution of the octopaminergic system in the insect brain.

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Accordingly, the fractional inhibitory concentration (FIC) and FIC index (FICI) were calculated for each of the combinations. The results showed distinct task sequencing effects in favor of initial practice on a closed loop task. Colorectal cancer (CRC) is one of the most common cancers in the what drug can replace lipitor world, having both high prevalence and mortality. Melasma is a uichronic, often relapsing skin disorder, with poor long-term results from all current therapies. Ninety-three forms were completed by children ages 2 to 16 years. As in transformed cells, normal mouse cathepsin L was secreted by COS cells. Separate subpopulations of cells encoded either saccade direction or direction error before the second saccade. In IPAH with narrow QRS, RV dyssynchrony is associated with RV dilation and eccentric hypertrophy pattern, suggesting a role of segmental wall stress heterogeneity as the major determinant of mechanical delay. These interventions could lead to better outcomes for adolescents with sickle cell disease. Does tramadol affect coagulation status of patients with malignancy?.

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After 4, 8, and 12 weeks of the operations, capillary vessel ink infusion, vascular endothelial growth factor ( VEGF) immunohistochemical staining and histological examination were conducted. Human immunodeficiency virus type 1 drug susceptibility determination by using recombinant viruses mebeverine dose bnf generated from patient sera tested in a cell-killing assay. Isoelectric focusing showed that the isoelectric point of STII is 9.7, indicating that the side chains of some of these basic amino acid residues project outside the molecule. There is no strong evidence against quality of life benefits associated with CSII or otherwise, with poor methodology and inconsistent assessment of quality of life clouding the issue. Past behavior predicted attitude in the domains of binge eating and smoking, but not in the domains of alcohol use, drunk driving, or marijuana use. Patients with unexplained iron deficiency anemia have a greater prevalence of colonic neoplasia, and should be evaluated for a colonoscopy. There are few epidemiological reports on the etiology of uveitis from areas within Asia. A contribution to the differential diagnosis of odnotogeneous cysts. We also devise adjusted V- and K-residuals to account for right censoring of any response. Nucleotide polymorphisms between parental lines were detected by DNA sequencing.

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The inhibition of aminoacyl-tRNA synthetases by acyl derivatives of amino acids. The results obtained indicate that the protein tyrosine kinase Syk interacts with multiple CD22-derived phosphopeptides in both immunoprecipitation and reverse Far Western assays. Burn wound assessment in porcine skin using indocyanine green fluorescence. In this study, we evaluated its analgesic efficacy over the first 48 postoperative hours after appendectomy performed through an open abdominal incision, in a randomized, controlled, double-blind clinical trial. F344 kidneys were transplanted orthotopically into bilaterally nephrectomized LEW recipients. Immunoscreening of a Candida albicans cDNA library in the expression vector lambda gt11 with rabbit polyclonal antibodies against the 37 kDa cell surface laminin receptor of C albicans resulted in the isolation of a cDNA clone of 0.9 kb. In addition, we demonstrated that ERK and p38 MAPK exerted diversified roles in the protection of LBP against ES-induced cellular damages. Standard heparin, low molecular weight heparin and aspirin are at present the only antithrombotic agents of proven value in the initial treatment of patients with an acute coronary syndrome.

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Hyaluronidase increases the biodistribution of acid alpha-1,4 glucosidase in the muscle of Pompe disease mice: an approach to enhance the efficacy of enzyme replacement therapy. The amplitude of modulation increased proportionally to rotational velocity, but the phase remained the same. Response of two-phase droplets to intense electromagnetic radiation. Ultrastructural analyses revealed the presence of five morphologically distinct types of hemocytes: prohemocytes, plasmatocytes, granulocytes, oenocytoids and macrophage-like cells. Our patient had the symptom of discharging pus in the left ear when he was about 1 year old. Vaccination rates are low in clinical practice, and public health and educational programs are needed to overcome barriers to facilitate timely implementation of these recommendations.

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Low skin reactivity to common inhalant allergens is frequently found in asymptomatic individuals as well as in patients with respiratory complaints. Membrane permeabilization underlies the enhancement of extracellular bioactivity in Shewanella oneidensis by a membrane-spanning conjugated oligoelectrolyte. Our results indicate that the PMv (but not aIPS) is involved in should you apply moisturizer before or after differin gel the deployment of the compensatory response in the presence of haptic perturbations during prehension. A small simulation study was conducted to illustrate the results and to compare results from TLME and PM. A quantitative structure-activity relationship for the modulation effects of flavonoids on p-glycoprotein-mediated transport. These results reveal a higher complexity to the regulation of rat epididymal segments than heretofore appreciated. However, at a larger dose of 300 mug, phentolamine frequently induced a biphasic chronotropic response, i.e., sinus deceleration followed by sinus acceleration. The present study was undertaken to evaluate the ability of FDG-PET to detect local residual tumor after treatment of laryngeal cancer.

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These results reveal that visual contact with the arms modulates their selection to perform reaching movements. In one experiment all these inhibitory effects of tea were statistically significant, whereas in the two other experiments many but not all of the inhibitory effects of tea were statistically significant. In this anatomical study, the anteroposterior curvature of the surface of 16 cadaveric distal femurs was examined in terms of radii and center point. Overexpression of bcl-2 protein in synovial sarcoma: a comparative study of other soft tissue spindle cell sarcomas and an additional analysis by fluorescence in situ hybridization. However, the cleocin tablets analysis revealed the absence of certain types of SNAREs found in metazoans and yeast, while suggesting the presence of original SNAREs as well as others with unusual localisation. The cavities in the cancellous bone could produce load modifications and consequent bone deformity. As positive controls V79 cells with CYP450-2E1 expression (V79-CYP450-2E1) and pooled human liver microsomes were used. Monocationic IL-aggregates generally exhibited higher partition coefficients compared to analogous dicationic ILs. This work was undertaken to review research addressing the cost-effectiveness of stroke-related diagnostic, preventive, or therapeutic interventions. Anginex-conjugated liposomes for targeting of angiogenic endothelial cells.

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PSA values collected in this study may serve as a reference for the Spanish working population, using the range described for decades, or even better, those relating to each age. The main areas of activity of the Ministry of Health and Public Welfare in 1972 and actions planned for 1973. Complete utilization of all available carbon sources in lignocellulosic biomass still remains a challenge in engineering Saccharomyces cerevisiae. The effects of concentrated salt solutions on the structure and the enzymatic activity of myosin molecules from skeletal and cardiac muscles. Comfortable and effective restoration of eye opening with maintenance of the blink is feasible using external static magnets and warrants further study. All respondents indicated that the continuing medical education programme created important physician networks absent in this post-conflict zone, updated professional skills, and improved professional confidence among participants. Study outcomes included cancer cell proliferation rates and angiogenic factor secretion from cancer cells. Thirty-day Hospital Readmissions in Patients with Non-ST-segment Elevation Acute Myocardial Infarction.

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