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Arachitol (Calcitriol)
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Arachitol

Arachitol is a hormonally-active, synthetic vitamin D analog prescribed to treat hypocalcemia, osteoporosis, and the prevention of corticosteroid-induced osteoporosis. Systemic Arachitol is FDA indicated to control hypocalcemia in patients on chronic renal dialysis, secondary hyperparathyroidism in those with chronic kidney disease not yet on dialysis, and hypocalcemia in patients with hypoparathyroidism and pseudohypoparathyroidism.

Other names for this medication:
Actical, Alfabond, Alfacalcirol, Apcical, Arachitol, Aristrol, Biocal, Bonestat, Bonetuf, Calasto, Calbovic, Calcibest, Calcikind, Calcirol, Calcor, Calday, Caldikind, Calgel, Calsonic, Calsure, Caltin, Caltop, Calvical, Calzem, Cholical, Devita, Dmcal, Duracal, Estovon, Koncal, Lctrol, Minroset, Ostonex, Politrol, Rical, Riecal, Rockbon, Roical, Rolsical, Romical, Solbiocal, Statbone, Tobalt, Trolec, Vezocal

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Reminyl, Viramune, Xeloda, Duricef, Rocaltrol, Zovirax, Motrin, Simbastatin, Plagerine, Lanzosec, Rotad, Ladlid, Stamlo, Alprodine, Bepride, Dapoxetina, Doyle,

Also known as: Calcitriol

Description

Generic Arachitol is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Arachitol are intestine and bone. Generic Arachitol receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Arachitol may also act on the kidney and the parathyroid glands. Generic Arachitol is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Arachitol has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Arachitol, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Arachitol in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Arachitol produces other independent beneficial effects. Arachitol is also known as Calcitriol. Generic Arachitol treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Arachitol is Calcitriol. Brand name of Generic Arachitol is Arachitol.

Dosage

Generic Arachitol is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Arachitol suddenly.

Overdose

If you overdose Generic Arachitol and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Arachitol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

It is especially important that you receive the right amounts of vitamins so that your baby will also get the vitamins needed to grow properly. Infants who are totally breast-fed and have little exposure to the sun may require vitamin D supplementation. However, taking large amounts of a dietary supplement while breast-feeding may be harmful to the mother and/or baby and should be avoided.

Only small amounts of alfacalcidol, calcifediol, calcitriol, or dihydrotachysterol pass into breast milk and these amounts have not been reported to cause problems in nursing babies.

It is not known whether doxercalciferol or paricalcitol passes into breast milk. Be sure you have discussed the risks and benefits of the supplement with your doctor.

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