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Aptric (Amitriptyline)

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Aptric is an antidepressant medication that is sometimes prescribed off-label to manage chronic back pain. It is one of the drugs in a class of drugs known as tricyclic antidepressants. Aptric is not a narcotic (opioid) drug, and there is not usually an addiction risk with the medication.

Other names for this medication:
Abamax, Amitar, Amitin, Amitrol, Amitryn, Amitryptyline, Amixide, Amizep, Amline, Amsha, Amtipax, Amypres, Bluneel, Cotrip, Gentrip, Goldep, Kamitrin, Latilin, Limbival, Mitrip, Mitryp, Normaline, Psycomer, Raitrip, Relidep, Ristryl, Ronet, Sereval, Tablin, Teedep, Tridep, Triplent, Tryptomec, Typlin, Vanatrip

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Also known as: Amitriptyline


Aptric target is the treatment of depression. Aptric is acting by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. It is tricyclic antidepressant. Generic name of Aptric is Amitriptyline. Aptric is also known as Amitriptyline, Amitryptyline, Amidon, Amitryn, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, Laroxyl, Saroten, Triptyl, Amitrip. Brand names of Aptric are Aptric, Endep, Vanatrip.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Aptric dosage information


If you overdose Aptric and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Aptric overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Aptric are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Aptric if you are allergic to Aptric components. Do not take Aptric if you are pregnant, planning to become pregnant, or are breast-feeding. Be careful with Aptric if you suffer from or have a history of a history of heart attack, stroke, bipolar disorder (manic-depression), schizophrenia or other mental illness, diabetes, overactive thyroid, glaucoma, problems with urination, heart disease, seizures. Be careful with Aptric if you are taking guanethidine (Ismelin), disulfiram (Antabuse), heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), quinidine (Cardioquin, Quinidex, Quinaglute), cimetidine (Tagamet). Avoid alcohol. Be careful! Taking Aptric you can become suicidal. Be careful when you are driving or operating machinery. Be careful with Aptric if you are going to have a surgery. It can be dangerous to stop Aptric taking suddenly.

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Adaptive numerical morphological filter for identifying chromatographic signals. Emission factors for PCDD/PCDF and dl-PCB from open burning of biomass. Follow-up of this cohort will allow the identification of clinical predictors of beta-cell failure in type 2 diabetic outpatients. Pathology confirmed squamous cell carcinoma arising from mature cystic teratoma of the ovary. In this study, we assessed the effectiveness of Eadyn to predict the arterial blood pressure response to a fluid challenge (FC) in preload-dependent, spontaneously breathing patients. Effect of arginine administration in patients with total parenteral nutrition and chronic renal failure. Then, we study the relationship between the epidemic rate and synchronization stability of these models and, in particular, obtain the conditions of local and global stability for epidemic synchronization. It will also enable identification of ankle injury risk factors that will lead to more efficient rehabilitation programs and injury prevention strategies.

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To determine the number of surgeons trained by the Department of Surgery, Faculty of Medicine, College of Health Sciences, University of Nairobi, since its inception in 1967. The apparent reality of hormesis raises the possibility of counterproductive effects of current dosage recommendations and limits for nutrients and pollutants. Converting apogeotropic into geotropic lateral canalolithiasis by headpitching manoeuvre in the sitting position. We now show that the activity of SHP is also increased by posttranslational methylation at Arg-57 by protein arginine methyltransferase 5 (PRMT5). Pharmacotherapy and cognitive behavioural therapy: similarly cost effective compared with community referral for disadvantaged women with major depression. There are also surgical approaches to target brain circuits via implanted stimulators placed in the brain or on cranial nerves. We compared 27 consecutive cases of ABAO identified in a university hospital between 2003 and 2007 with 311 unselected cases of ischemic stroke from two 4 month surveys. We retrospectively investigated 1,100 myocardial perfusion scintigraphies taken between January 2011 and December 2012 at Canakkale Onsekiz Mart University Medical Faculty Nuclear Medicine Department.

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Arboviruses are maintained in a natural cycle that requires blood-sucking arthropod and vertebrate hosts. Reversal of atrial electrical remodeling following cardioversion of long-standing atrial fibrillation in man. They are now arranged in all three mutually perpendicular directions. In our sample, the presence of depression seems to impact on the short-term control of T2DM. Interestingly, the intracellular reactive oxygen species (ROS) level increased significantly under J series metabolites treatment and, incubation with N-acetyl-L-cysteine or glutathione reduced ROS production and cell death significantly. Excitatory GABA actions, induced by altered expression of chloride transporters (KCC2/NKCC1), can contribute to seizure generation in temporal lobe epilepsy. It treats in depth some of the complications such as periodontal disease, fungal infection and salivary dysfunction while other complications are mentioned briefly.

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Radioisotope-antibody conjugates selectively target bone marrow prior to stem cell therapy. Results of the use of an automated system of management at a municipal teaching hospital. FISH analysis of uncultured interphase amniotic fluid cells from a male fetus revealed two signals using an alpha-satellite X-chromosome DNA probe. Differential effects of caffeine and perchlorate on excitation-contraction coupling in mammalian skeletal muscle. Design, synthesis, and biological evaluation of combretastatin nitrogen-containing derivatives as inhibitors of tubulin assembly and vascular disrupting agents.

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Echocardiographic evaluation of the serial changes in cardiac functions before and after surgery of valvular heart diseases and the left ventricular reserve by the dynamic exercise. None of the other parameters studied was shown to be a significant predictor of success. We assessed the lower urinary tract symptoms (LUTS) and urodynamic findings in patients with neuromyelitis optica spectrum disorders (NMO-SD), a recently defined neurological disease. This method permits the efficient activation of a given protein (for example, an enzyme) in its native cellular context within minutes. comparative cross-sectional survey with a non probabilistic sample at a primary care unit was done. However in the midst of our economic recession we are noticing an increasing number of these injuries.

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The received Doppler signal was stable but it proved sensitive to pathophysiologic changes in flow. Mineralized ring, an elongated tubular structure ensheathing bone metaphysis, is described at successive stages of long bone growth. Laparoscopic versus abdominal myomectomy: practice patterns and health how much does protonix usually cost care use in British Columbia. We report a successful percutaneous repair of a brisk left anterior descending coronary artery perforation by the implantation of a Magic Wallstent. Tetanus toxoid (TT) was assessed as a positive marker for avian influenza (AI) virus vaccination in chickens, in a vaccination and challenge study. Glial cell line-derived neurotrophic factor and synaptophysin expression in pelviureteral junction obstruction. The aim of this in vitro study was to determine the elution kinetics of 14 different high-dose ALACs. Emergence of tumors in young animals treated with azathioprine and ifosfamide, including a histologic assessment of the neoplasms.

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The aim of this study was to investigate Candida carriage and species in Maras powder users and non-users. Results of the study led to conclude that an earlier timing of allogeneic hematopoietic stem cell transplantation can be recommended in order to treat patients who would otherwise suffer an early relapse. Simultaneously, social concern about environmental sustainability rises every day and, as a consequence, improvement on waste treatment systems is being demanded. To compare the efficacy of doxycycline plus methotrexate (MTX) versus MTX alone in the treatment of early seropositive rheumatoid arthritis (RA), and to attempt to differentiate the antibacterial and antimetalloproteinase effects of doxycycline. Our study is aimed at analysing patients diagnosed with mad honey poisoning and their behaviour towards the consumption of this honey after diagnosis. In contrast to adulthood, little is known about the potential effects of methamphetamine exposure on cognition in adolescent mice. The proposed new application technique ensures that more sunscreen will be used and that it imdur 60 mg tablet will be applied more evenly. Physician division of labor and patient selection for outpatient procedures. Studies of the efficacy and potential hazards of methylene blue therapy in aniline-induced methaemoglobinaemia.

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Angiosarcoma of the scalp and use of a cordless (portable) telephone. Longevity of cemented femoral components is dependent upon many factors. InsightII and MOPAC 6.0 molecular modeling package were used to calculate the free energy of hydration (delta Ghydration), the energy of the highest occupied orbital (EHOMO), and the energy of the lowest unoccupied orbital (ELUMO) for each QA ion, respectively. Functional studies of discriminative and prognostically important microRNA may provide new insights into the biology of pediatric acute lymphoblastic leukemia. These data suggest that the antimotigenic and anticollagen effects of PTX were mediated predominantly through a cAMP-PKA effector pathway. Moreover, the inclusion of this technique in the new definition of remission is being validated. Formula optimization based on artificial neural networks in transdermal drug delivery. In all cases the catheter tip had been dislodged and was proximal to its correct position, allowing the stomach to be directly infused with 5-FU. Work-related fatalities among youth ages 11-17 in North Carolina, 1990-2008.

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