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Aprical (Nifedipine)

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Aprical is a calcium-channel blocker. It affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work the heart has to do. This medicine is used to treat chest pain caused by angina.

Other names for this medication:
Adefin, Adipine, Antrolin, Belnif, Calcibloc, Cobalat, Conducil, Cordipin, Corinfar, Epilat, Farmalat, Fenamon, Glopir, Hexadilat, Myogard, Nicardia, Nifcal, Nifecap, Nifeslow, Nifin, Nipidin, Nyefax, Pabalat, Sidalat, Tenif, Tredalat

Similar Products:
Astelin, Zyprexa, Lopid, Cytoxan, Geodon, Seroquel, Loxitane, Persantine, Klitopsin, Alwel, Vomcid, Fulterm, Beltrax, Xavin, Glubose,

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Aprical. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Aprical and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Recently, a greatly increased number of macrofossil and pollen analytical records from Australasia and southern South America has permitted, for the first time, a comprehensive overview of past vegetation and climate change in southern temperate ecosystems. Plasma leptin response to oral glucose tolerance and fasting/re-feeding tests in rats with fructose-induced metabolic derangements. Pure optical dephasing dynamics in semiconducting single-walled carbon nanotubes. Effects of respiratory syncytial virus infection on the airway neuronal plasticity and its relationship to the bronchial hyperresponsiveness in rats. The First International Teleconference in Ophthalmology was held during March 1998 between five sites in the UK, USA, Greece and Malaysia. The psychiatry of vertebro-basilar insufficiency with the report of a case. 1,2-Hydride Shift in the Biosynthesis of Pinguisane-type Sesquiterpenes. Analyzing the content, of other physiologically active components will be necessary.

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Lymphovascular invasion (LBVI) including lymphatic (LVI) and blood (BVI) vessel invasion is a critical step in cancer metastasis. As a result, conventional tools that are based on reductionist approach are not adequate. The saturation capacity for Hg(II) exceeds 2 g g(-1) , more than doubling the best thiol-functionalized sorbents in the literature. Despite similar infarct size, females developed less pronounced abnormalities of LV diastolic filling. The analysis presented here combines the application of a correlation-based clustering method with a graphical color map allowing intuitive visualization of patterns within a large table of expression measurements. Why conventional exhaled breath condensate pH studies cannot provide reliable estimates of airway acidification. Chikungunya virus infections among travelers-United States, 2010-2013. The amount of HC absorbed from the liposome-gel after 8 h into the SC-removed skin was less than one third of that from the conventional ointment.

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Using the overlay assay to qualitatively measure bacterial production of and sensitivity to pneumococcal bacteriocins. We studied patients with elevated serum levels of prostate specific antigen (PSA) and low urinary tract symptoms (LUTS) aiming to determine whether histological examination after transurethral resection of the prostate (TURP) could detect prostate cancer (PC) missed by previous routine transrectal ultrasound (TRUS) guided sextant prostate biopsies. Although the pathogenesis of gonadal dysfunction in thalassaemia is known to be the consequence of iron overload, this study demonstrates that genotype acts as an independent variable, contributing to the development of SA in thalassaemic women. Variation of ACh concentration over time may modulate the complexity of atrial arrhythmias. Nerve-stimulated secretion of calcium by rat submandibular gland. Previously, we have shown in other upper and lower airway diseases that immunoglobulin free light chains (FLCs) are increased and may be involved in initiating a local inflammation.

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Norwegian lemmings exhibited a large-scale outbreak synchronously with gray-sided voles in Finnmark, northern Fennoscandia, during 2006 to 2007 for the first time in two decades. By analysis of meiotic recombinations in affected individuals, the critical region was restricted to the 7-cM interval between D10S198 and D10S1795. Hospital acquired pneumonia (HAP) add to the morbidity and mortality of traumatic brain-injured patients. Here we describe a new in vitro system that utilizes adult human pancreatic islet-enriched fractions to generate hormone-producing cells over 3-4 weeks of culture. To characterize the left ventricular (LV) regional deformation patterns and identify normal values of left ventricular strains from tagged magnetic resonance imaging (MRI) in a population with low-risk-factor (LRF) exposure. A 10-year prospective study of respiratory disease and depression and anxiety in adulthood. Gender, rural residence, and poverty are identified as risk factors for reduced access to health care services, lower rates of health care service utilization, and poorer health outcomes. Lamellar bone occurs also in this bone around vascular channels but rarely in the form of typical osteons. Ductal stenting is a good alternative strategy for left ventricular retraining in TGA with regressed LV even in patients with occluded ducts.

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To inform practitioners about this rare condition and to emphasize the importance of surgical treatment. The Interpersonal Support Evaluation List (ISEL) was used to measure the functional aspects of the perceived availability of social support. The role of ketotifen in the prevention of testicular damage in rats with experimental unilateral undescended testes. Giant-cell arteritis of temporal localization and hepatic granulomatosis. These include a zona pellucida binding domain, which is present in a number of proteins such as the zona pellucida sperm binding proteins, and uromodulin, In addition, there is a repeat of a motif called CUB domain, which exists in a number of genes involved in development and differentiation such as bone morphogenetic protein 1 (BMP1). In any case of cardiogenic shock, hypocalcemia should be included in the differential diagnosis and must be investigated.

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Effects of biotechnical management procedures on blood parameters in gilts. OSAS should be excluded in patients with Melnick-Needles syndrome and, if diagnosed, nasal CPAP may be a helpful treatment. Little is known about the way in which the psychiatrists and attorneys on these committees arrive at their decisions. At baseline, the patients had low serum concentrations of free thyroxin and slightly elevated TSH. This study aimed to evaluate the mortality pattern in children seen danocrine cost at Federal Medical Centre Umuahia (FMCU) Abia state, South Eastern Nigeria. Conostegia xalapensis (Melastomataceae): an aluminum accumulator plant.

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Segmentation of volumetric MRA images by using capillary active contour. The findings of this study suggest that high-risk elders with significant cardiac problems may benefit from a care program that emphasizes collaborative, coordinated discharge planning and home follow-up that includes telephone and home visits by APNs. Several studies support the notion that T cells are activated only by TCR/pMHC interactions that are above a threshold of half-life. Do practice characteristics explain differences in morbidity estimates between electronic health record based general practice registration networks?. Omega-3 carboxylic acids (Epanova): a review of its use in patients with severe hypertriglyceridemia.

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An increased cancer risk in patients with sarcoidosis has been suggested, although results are conflicting in a number of case-control and cohort studies. For this purpose, we separated committed progenitor populations from primitive hematopoietic cells in DHFR transgenic marrow by counterflow elutriation (CE). Prevalence of smoking and second-hand smoke exposure: differences between Spanish and immigrant pregnant women. This cohort also illustrates that patients with chondrosarcomas have better long-term survival rates than patients with chordomas of the cranial base. The chromatographic properties of four phenyl-bonded phases with different structures were studied. Examination of Golgi-impregnated rat brains reveals that three main cell types can be distinguished in the nucleus of the lateral olfactory tract (NLOT). Furthermore, a logistic regression analysis was performed to determine the independent risk factors for colorectal adenoma in these subjects.

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This document provides recommendations for TOE probe decontamination based on the available evidence, expert opinion, and modification of the current British Society of Gastroenterology guidelines. Investigations into the mechanisms responsible for the effects of serum have identified specific receptors, some of which appear to be involved in receptor-mediated transcytosis and endocytosis via noncoated plasmalemma vesicles (also known as caveolae). Urinary zearalenone levels in girls with premature thelarche and idiopathic central precocious puberty. Temperature gradient sensor based on a long-fiber Bragg grating and time-frequency analysis. Furthermore, phenylacetic acid was converted to phenylacetyl-CoA by the catalysis of phenylacetate-CoA ligase in strains ST-5 and ST-10. Opportunities for practice development abound in the area of learning related vision problems. Immunohistochemical differences in p53 expression were correlated with smoking status.

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Allocation of household responsibilities influences change in dietary behavior. Liver stiffness measurement (LSM) using transient elastography (FibroScan) is a useful tool to assess fibrosis in various chronic liver diseases. The aim of the study was to define, before any sort of cleaning procedure, if there is any epithelial inclusion inside the ossicles of patients with cholesteatoma and if the findings could be correlated with surgical aspect of cholesteatoma. Intercellular bridges with continuous cytoplasm were zithromax 500mg tablets side effects observed between fetal Leydig cells (FLCs) in the early postnatal period. Gender differences in outcomes may be improved through durable revascularization strategies and close postoperative follow-up care targeted to women. The present paper compares echostructure of the thyroid gland with the level of hormones--triiodthyronine (T3), thyroxine (T4), thyroidstimulating hormone (TSH) and thyroglobulin (tg) and thyroglobulin autoantibodies (tg-ab).

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Cytosolic phospholipase A(2) (cPLA(2)) catalyzes release of arachidonic acid from membrane phospholipids to initiate the synthesis of prostaglandins and other inflammatory mediators. An evaluation of information available on the internet regarding minimally invasive hip arthroplasty. For all subjects, the PG method showed on average approximately 10 times higher gamma production rates than the PET method before, and 60 to 80 times higher production after including the washout correction and acquisition time delay. Prevention of cardiovascular events in variant angina by long-term diltiazem therapy. Twenty family members of cancer patients were included in the study shortly after the diagnosis. This ineffectiveness is due, in part, to the involvement of additional effectors in Ras-dependent cancer growth, such as the Rac small GTPase and the p21-activated serine-threonine kinases (PAK). Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) has become a rapid and sensitive tool in proteomics, notably with maxolon drug group the new instrumental improvements. DNA analysis and Western blot analysis did not show significant differences in ribosomal protein S3 between FA cells and cells from healthy individuals. An extended discussion of our surgical technique for aneurysm bypass is included. These targets are based on epidemiological studies of complication development, but so far have not adequately addressed the adverse effects associated with lowering HbA1c towards the normal range.

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