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Apodruff (Ketoconazole)

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Apodruff is an antifungal medicine. It is used to treat skin infections caused by fungi. These include athlete’s foot, ringworm, vaginal thrush, and sweat rash. It works by killing and stopping the growth of fungi, thereby clearing the infection and relieving the symptoms.

Other names for this medication:
Apodruff, Arcolane, Clinhair, Danclear, Dancure, Dandcare, Danket, Danruf, Danstop, Emvate, Flakfree, Forfora, Fungicide, Funginoc, Fungizole, Hairdruff, Hyphoral, Kekona, Keticon, Ketoco, Ketodan, Ketosh, Ketosis, Ketotar, Ketovate, Ketozoe, Kuric, Nizral, Nodan, Ocona, Phytoral, Rivtar, Sebotar, Silkin, Triben, Xolegel

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Also known as: Ketoconazole


Apodruff Topical (for the skin) is an antifungal medicine used to treat infections such as athlete's foot, jock itch, ringworm, and seborrhea (dry, flaking skin or dandruff).

Apodruff Topical is also used to treat a fungal infection called pityriasis, which causes scaly discolored patches on the skin of the neck, chest, arms, or legs.


This section provides information on the proper use of a number of products that contain ketoconazole. It may not be specific to Apodruff A-D. Please read with care.

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine is for use on the skin only. Do not get it in your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

For patients using the cream:

Apply enough cream to cover the affected and surrounding skin areas, and rub in gently. To help clear up your infection completely, it is very important that you keep using the cream for the full time of treatment, even if your symptoms begin to clear up after a few days. Since fungus or yeast infections may be very slow to clear up, you may have to continue using this medicine every day for up to several weeks. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses.

For patients using the foam:

Wash your hands before and after using this medicine. Do not spray the foam directly on your hand because it will begin to melt as soon as it touches your skin. Instead, spray the foam into the cap of the medicine can or other cool surface. Then dip your fingertips into the foam to pick up small amounts of the medicine, and apply to the affected skin areas. Gently massage the foam into your skin until it disappears. If you are treating skin areas with hair, such as your scalp, move any hair away so the foam can be applied directly to the affected skin. This medicine is flammable. Do not use it near heat, an open flame, or while smoking. Do not puncture, break, or burn the medicine can.

For patients using the gel:

Wash your hands before and after using this medicine. Apply enough ketoconazole gel to cover the affected and surrounding skin areas, and rub in gently with your fingertips. After applying this medicine, do not wash the affected area for at least 3 hours. Cosmetics (makeup or sunscreens) may be used on the treated skin areas no sooner than 20 minutes after this medicine is applied. This medicine may be flammable. Do not use it near heat, an open flame, or while smoking.

For patients using the 1% shampoo:

Wet your hair and scalp well with water. Apply enough shampoo to work up a good lather and gently massage it over your entire scalp. Rinse your hair and scalp with warm water. Repeat application. Rinse your hair and scalp well with warm water, and dry your hair.

For patients using the 2% shampoo:

Wet your hair and scalp well with water. Apply the shampoo to the skin of the affected area and a wide margin surrounding this area. Work up a good lather and leave it in place for 5 minutes. Rinse your hair and scalp well with warm water, and dry your hair.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For cream dosage form: For cutaneous candidiasis, tinea corporis, tinea cruris, tinea pedis, or pityriasis versicolor: Adults—Apply to the affected area of the skin and the surrounding area once a day. Children—Use and dose must be determined by your doctor. For seborrheic dermatitis: Adults—Apply to the affected area of the skin and the surrounding area two times per day. Children—Use and dose must be determined by your doctor. For foam dosage form: For seborrheic dermatitis: Adults—Apply to the affected area of the skin and the surrounding area two times per day for 4 weeks. Children—Use and dose must be determined by your doctor. For gel dosage form: For seborrheic dermatitis: Adults, teenagers, and children 12 years of age and older—Apply to the affected area of the skin and the surrounding area once a day for 2 weeks. Children younger than 12 years of age—Use and dose must be determined by your doctor. For 1% shampoo dosage form: For dandruff: Adults—Use every 3 or 4 days for up to 8 weeks. Then use only as needed to keep dandruff under control. Children—Use and dose must be determined by your doctor. For 2% shampoo dosage form: For pityriasis versicolor: Adults—Use once. Children—Use and dose must be determined by your doctor.


An overdose of Apodruff Topical is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Apodruff are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Apodruff Topical if you are allergic to ketoconazole.

Ask a doctor or pharmacist if this medicine is safe to use if you have:

asthma or a sulfite allergy; an allergic reaction to an antifungal medicine, such as clotrimazole, econazole, or miconazole.

Ask a doctor before using this medicine if you are pregnant.

You should not breast-feed while using Apodruff Topical.

Always follow directions on the medicine label about using this medicine on a child.

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