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Apcical (Calcitriol)
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Apcical

Apcical is an active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. Apcical is a biologically active calcitrophic hormone with anti-osteoporotic, immunomodulatory, anticarcinogenic, antipsoriatic, antioxidant, and mood-modulatory activities.

Other names for this medication:
Actical, Alfabond, Alfacalcirol, Alfarich, Biocal, Biocitral, Calbec, Calbory, Calcibest, Calcicare, Calcikind, Calcimet, Calcor, Caldix, Calfa, Calgel, Calosto, Calotec, Calsure, Caltin, Caltop, Calvical, Citroj, Coecoral, Denscal, Devita, Dmcal, Estovon, Ikmag, Koncal, Nutribone, Osteobel, Ostonex, Politrol, Riecal, Ritoca, Roical, Solbiocal, Statbone, Vezocal

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Prometrium, Leukeran, Imdur, Ovral, Cozaar, Floxin, Effexor, Valtrex, Flutivate, Tetra, Bonetuf, Ralista, Promethazine, Melalite, Lynacold, Tanlozid,

Also known as: Calcitriol

Description

Generic Apcical is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Apcical are intestine and bone. Generic Apcical receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Apcical may also act on the kidney and the parathyroid glands. Generic Apcical is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Apcical has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Apcical, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Apcical in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Apcical produces other independent beneficial effects. Apcical is also known as Calcitriol. Generic Apcical treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Apcical is Calcitriol. Brand name of Generic Apcical is Apcical.

Dosage

Generic Apcical is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Apcical suddenly.

Overdose

If you overdose Generic Apcical and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Apcical are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Problems in older adults have not been reported with intake of normal daily recommended amounts. Studies have shown that older adults may have lower blood levels of vitamin D than younger adults, especially those who have little exposure to sunlight. Your health care professional may recommend that you take a vitamin supplement that contains vitamin D.

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A case of acute gastric volvulus associated with eventration of the diaphragm in a previously well 6 year old child is reported. The role of CC chemokine receptor 6 in host defense in a model of invasive pulmonary aspergillosis. In-silico prediction of key metabolic differences between two non-small cell lung cancer subtypes. Class time was focused on active-learning and case-based exercises. The future of surgical endoscopy may be the shared entity of NOTES, which further integrates endoscopy, gastroenterology, and minimally invasive and general surgery. In a combined sample of patients and controls, six of eight items were significantly correlated with the SC task assessing the same domain, providing modest evidence of convergent validity. This study demonstrates the use of two different classes of anti-angiogenic agents, one targeting the Vascular Endothelial Growth Factor (VEGF) pathway involved with vessel sprouting and the other targeting the Angiopoietin/Tie2 pathway involved in vascular destabilization. Public health strategies are needed to facilitate participation in physical activity, especially for women, elderly, and less educated individuals. Laparoscopic treatment for extensive endometriosis has been described but should only be performed by very experienced operative laparoscopists.

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A para-ureteric pseudo-cyst of the middle third of the ureter was observed following a sympathectomy. Different species-specific chromosome translocations in Triticum timopheevii and T. Comparison of continuous infusions and bolus injections of 5-fluorouracil with or without leucovorin: implications for inhibition of thymidylate synthase. Subsequently, we use this expert model as a reference model in the definition of an objective metric to evaluate performance of surgeons with different abilities. Iran has had incremental incidence of traffic accident mortality since introduction of mechanization about a century ago. A case of recurrent intramural uterine stromal tumor with epithelial differentiation effectively treated with oral low-dose administration of etoposide. Donor leukocyte infusion for relapsed ANLL after allogeneic BMT and the use of interferon alpha to induce graft-versus-leukemia effect.

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A comparison cohort of 84,996 participants was formed by age-, gender-, income-, and urbanization-matched controls. Recent experiences with mobile-phone technology to access and update the BAMWSP data in the field are also described. The results suggest that, like in other eukaryotes studied, the control of meiotic crossover formation also in D. It suggests a role of free radicals in the pathogenesis of certain types of acute hepatic failure. The effect of antibodies against some neurotrophic factors (S-100b protein, CSL, etc.) on elaboration, storage, and retrieval of acoustic startle habituation and concomitant freezing behaviour, was found to be dose-dependent in adult rats. Thoracoscopic enucleation of a large esophageal leiomyoma using a three thoracic ports technique. coli induces significant proliferation in lymphocytes obtained from milk, but fails to stimulate blood lymphocytes.

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Localization of neurofibromin to keratinocytes and melanocytes in developing rat and human skin. Interictal epileptiform discharges (IEDs) constitute a perturbation of ongoing cerebral rhythms, usually more frequent during sleep. Hepatocellular carcinoma (HCC) is a major pathological type of primary liver cancer. Antismoking television advertising and socioeconomic variations in calls to Quitline. We determined growth selection by cell enrichment assay and cloning efficiency after treatment with 5 micromol/L 5-FU, assayed nucleic 3H-5-FU incorporation, and analyzed the cell cycle by flow cytometry.

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To elucidate the whole diversity of N1 influenza viruses from a dynamic view, 202 neuraminidase (NA) sequences of N1 subtype influenza isolates were selected and analyzed in this study. The Comprehensive Meta-Analysis version 2 was used for meta-analysis. Differences in linkage disequilibrium structure and heterogeneity in allelic effects are expected to play a role in the associations observed between populations. The range of possibilities suggested include tonic underarousal and phasic abnormalities such as hypersensitivity to reward and/or reduced sensitivity to negative consequences associated with losses. Nonspecific immunoglobulin replacement in lung transplantation recipients with hypogammaglobulinemia: a cohort study taking into account propensity score and immortal time bias.

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The patients were followed up for 5 to 10 years from the date of coronary arteriography. Chimeric bifunctional oligonucleotides as a novel tool to invade telomerase assembly. Indicators of natural resistance in patients with pulmonary tuberculosis. The aim of this research was to provide convergent validity evidence for the use of the Godin-Shephard Leisure-Time Physical Activity Questionnaire (GSLTPAQ) to classify breast cancer survivors into active and insufficiently active categories. Simultaneous ablation of H3f3a and H3f3b in folliculogenesis resulted in early primary oocyte death, demonstrating a crucial role for H3.3 in oogenesis. It is shown that this pathology is characterized by the predominance of marked degenerative, necrotic and inflammatory changes over the reparative processes. Among the eight families of Anopheles willmori derived from individual wild-caught females collected from Chiangmai Province (northern Thailand) and examined, four isofemale lines showed variation in the X chromosome, including the normal X1 and three aberrant types (X3, X4 and XL). A total of 57 patients was found to have a chromosome abnormality, including five with a balanced structural rearrangement.

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As DNA barcoding is an effective tool for resolving species complexes and analyzing species distributions, we used this approach to analyze genetic diversity in the B. Elements of the hAT transposon family, such as the maize activator (Ac), have been discovered in a large number of eukaryotic species. The high incidence of these infections would be accounted for by the poor hygienic conditions due to lack of bathing facilities due to scarcity of water and the consequent sweat retention and overgrowth of cutaneous infective organisms. The relative stability between both conformations and the agreement with some experimental values is also discussed. The limit of distribution of three species is extended east to the Gulf of Carpentaria, from Kenya for C. These strains are representative of a pathovar called enteropathogenic E. Anatomical, morphological, and phytochemical effects of inoculation with plant growth- promoting rhizobacteria on peppermint (Mentha piperita).

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Aerobic and anaerobic metabolic changes due to work in relation to the hemodynamic adaptation in normal subjects and patients with heart diseases. In order to study the components that interact with BCR complexes in the cell it is essential that they are accessible to biochemical studies. The evaluation should include chest X-ray, echocardiography, and barium swallow. In the present study, we investigated the anti-proliferative effects of formononetin on human non-small cell lung cancer (NSCLC), and further elucidated the molecular mechanism underlying the anti-tumor property. Therapeutic drug monitoring was performed in plasma and dialysate. The aim of the study was to determine if a more rational therapeutic approach could be devised for neuroleptic resistant psychotic patients treated for months and years with clozapine. The larger morphine infusion dose also increased nociception in both sexes on Days 4 and 6. First-line therapy with moderate dose capecitabine in metastatic breast cancer is safe and active: results of the MONICA trial. The P300 latencies for the target trials with acute sinusitis levaquin dose SSNA bursts were shorter than those for the target trials without SSNA bursts. Hyperthyroidism per se probably accounts for the increased cerebrovascular mortality after RAI treatment.

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Co-immunoprecipitation with anti-cdk4 antibody showed that induced p21 associates with cdk4 and that its kinase activity is reduced by TGF-beta, which kinetically correlates closely with G1 arrest following TGF-beta treatment of both cell lines. The purpose of this study was investigate the hypothesis that specific ECG features identify an epicardial origin for RV VT. Cyanogen bromide-cleaved transferrin is separated into three fragments (CN-A, CN-B and CN-C) by gel filtration with Sephadex G-100. EGF-induced activation of MMP7 and MMP13 can be both inhibited by use of an inhibitor for EGFR. Immunohistochemical staining what schedule drug is xanax considered for CAM 5.2 and S100 markers, as well as morphological assessment were performed.

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Here we investigated the impact of cortical state on the population coding of tones and speech in the primary auditory cortex (A1) of gerbils, and found that responses were qualitatively different in synchronized and desynchronized cortical states. Syndrome of familial dwarfism and high plasma immunoreactive growth hormone. Giant enhancement of band edge emission in ZnO and SnO nanocomposites. Controversies in transfusion medicine: should a febrile transfusion response occasion the return of the blood component to the blood bank?. : Maximum cross-sectional area was greater during sitting than during what is generic zyrtec called supine posture at both retropalatal (median (10th-90th percentile): 1.91 (1.52-3.40) versus 1.25 (0.65-1.97) cm) and retroglossal (2.42 (1.72-3.84) versus 1.75 (0.47-2.35) cm) airways. Spatial distribution of stabilizer-derived nitroxide radicals during thermal degradation of poly(acrylonitrile-butadiene-styrene) copolymers: a unified picture from pulsed ELDOR and ESR imaging. Systolic compression of the septal perforator arteries is not a pathognomonic sign of idiopathic hypertrophic subaortic stenosis. The calculated isotherm for adsorption of hard spheres using scaled particle theory for hard discs agrees well with that calculated from the hard disc virial expansion. Secondary thematic analysis of 65 in-depth narrative interviews with family members of people in vegetative or minimally conscious states. Although one death has been reported, other cases have shown complete recovery.

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Effects on nutritional and inflammatory status: a phase II trial. A retrospective chart review (2002-2009) was conducted in our institution. Epidermal growth factor activates telomerase activity by direct binding of Ets-2 to hTERT promoter in lung cancer cells. Keratoconus (KC) is a genetically heterogeneous corneal dystrophy with unknown etiology that causes loss of visual acuity. Effect of tannic acid on liver levels of neurontin cost generic vitamin A in rats maintained on balanced diets or deprived of this vitamin.

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Anatomic significance of magnetic resonance imaging findings in hip fracture. Synthesis and G-quadruplex binding studies of new 4-N-methylpyridinium porphyrins. Hepatitis B and C seropositivity among nursing students at a Turkish university. Similarly, selection for hyaluronic acid binding sites may enable the most mature spermatozoa to be selected for IVF or ICSI. A review of the current literature suggests that symptomatic cardiac papillary fibroelastomas should be surgically removed, whereas asymptomatic lesions that are left-sided, large (larger than 1 cm) or mobile should be considered for surgical excision.

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Under analysis were results of treatment of 141 patients with infected pseudoarthroses of the tibia. To illustrate the importance of a careful differential diagnosis in children presenting with torticollis. Recognition and treatment of evolving critical illness is a fundamental element of hospital care. The importance of a large spectrum immunohistochemistry as first diagnostic approach to any undifferentiated small-cell malignant tumor is stressed, together with the knowledge of the different immunoreactivity patterns. The intraoral approach to the canine extraction can be buccal or palatal depending on the position of the tooth. Consistent with this idea, loss of the Not4-interacting protein Ubc4, a known ubiquitin-conjugating enzyme, decreases H3K4me3. But if symptoms persist, with no significant improvement after 6 months of finasteride or 2 to 3 months of an alpha-1 blocker, consider a urology consultation. The tumor referencing method presented in combination with the statistical eye model introduced in the past has the potential to enable noninvasive treatment and may improve quality, efficacy, and flexibility of external beam radiotherapy of intraocular tumors. Purification and characterization of an endogenous inhibitor specific to the Z-Leu-Leu-Leu-MCA degrading activity in proteasome and its identification as heat-shock protein 90.

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