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Angilock (Losartan)

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Angilock belongs to a family of medications known as angiotensin II receptor blockers. These medications are used in adults and children over the age of six to lower mild-to-moderate hypertension (high blood pressure).

Other names for this medication:
Angilock, Aratan, Cardzaar, Covance, Cozaarex, Enromic, Forzaar, Hilos, Lavestra, Logika, Lohyp, Lopernal, Losaprex, Losarb, Losartec, Losazid, Lostan, Lotan, Lotar, Medzar, Normatens, Osartan, Ostan, Ozarium, Portiron, Prelow, Psycholanz, Ranlozar, Rasoltan, Sartens, Sarvastan, Sarve, Simperten, Tarnasol, Tensartan

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Also known as: Losartan


Angilock is indicated for the treatment of hypertension in adults and pediatric patients 6 years of age and older, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and nonfatal cardiovascular (CV) events, primarily strokes and myocardial infarction. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including losartan.

Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than 1 drug to achieve blood pressure goals. For specific advice on goals and management

Angilock is indicated to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, but there is evidence that this benefit does not apply to Black patients

Angilock is indicated for the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria in patients with type 2 diabetes and a history of hypertension. In this population, Angilock reduces the rate of progression of nephropathy as measured by the occurrence of doubling of serum creatinine or end stage renal disease


Take Angilock tablets orally with or without food. Do not crush or chew it. Take Angilock once or twice a day at the same time. If you want to achieve most effective results do not stop taking Angilock suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Angilock are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Changes in renal function including acute renal failure can be caused by drugs that inhibit the reninangiotensin system and by diuretics. Patients whose renal function may depend in part on the activity of the renin-angiotensin system (e.g., patients with renal artery stenosis, chronic kidney disease, severe congestive heart failure, or volume depletion) may be at particular risk of developing acute renal failure on COZAAR. Monitor renal function periodically in these patients. Consider withholding or discontinuing therapy in patients who develop a clinically significant decrease in renal function on Angilock.

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As a class of molecular chaperones, small heat shock proteins (sHsps) usually exist as multi-subunit spherical oligomers. On the basis of the available evidence recommendations for practice were graded using the Oxford Centre for Evidence-based Medicine classification. The Progression of Bone Mineral Density Abnormalities After Chemotherapy for Childhood Acute Lymphoblastic Leukemia. Two rare TSH receptor amino acid substitutions in toxic thyroid adenomas. Furthermore, this work represents the first evidence for functional ClC-K chloride channel expression within the lung. Catabolic signaling and muscle wasting after acute ischemic stroke in mice: indication for a stroke-specific sarcopenia. A significantly higher percent of cardiomyocytes with autophagosome accumulation underwent necrosis in CR-Csn8KO hearts. The aim of the present study was to evaluate the ability of a lactonase called SsoPox-I to reduce the mortality of a rat P. In 102 persons, duodenal and stool examinations revealed four and five cases of Giardia infection, respectively. A prospective study of serum zinc concentration in children with celiac disease.

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Risk factors for cardiovascular disease in professors from a public university. Effects of recent psychoanalytic theories and therapy concepts on the treatment technics of sex offenders. Consistent gray matter reductions in all MDD patients relative to healthy controls were identified in the bilateral anterior cingulate cortex (ACC), right middle and inferior frontal gyrus, right hippocampus and left thalamus. It was a cohort study conducted in 3 waves in 1991, 1996-1997, and 2001-2002. Through reviewing the relevant literature, we suggested the possibility of common neurobiology between the two psychiatric phenomena and direction of research on aggression in IAD. Multiplexing samples by differential mass tagging in LC-MS/MS measurement of 25(OH)D2 and 25(OH)D3 allows for reliable quantification, with throughput increased over standard methods by the multiplexing factor. Beside structural environmental components as extracellular matrix (ECM) or hypoxia, stromal cells as macrophages, endothelial cells, and cancer-associated fibroblasts (CAFs) play a definite role in cancer progression. The trial was registered with Current Controlled Trials (registration number: ISRCTN12376468) on 10 July 2012. The aerobic fitness of elite judokas may be improved by adding aerobic routines to the normal training enhancing the recovery capacity.

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The serum samples from 20 patients with adenomyosis and from 20 patients with endometriosis were analyzed using iTRAQ technology to detect the differential expression of proteins. Pediatricians rated using the pass as significantly more acceptable than letting children sleep with parents and equivalent to ignoring. In this study, we investigated if extending distance-dependent pairwise atomistic statistical potentials to corresponding interaction functions that are conditional on a third interacting body, defined as quasi-three-body statistical potentials, could model details of three-body interactions. In this paper, we aim to determine whether shrubs growing in a non-Mediterranean climate region exhibit relationships between their fire-response strategy and leaf traits. Angiotensin II type 1 receptor blockade improves beta-cell function and glucose tolerance in a mouse model of type 2 diabetes. However, the threshold odour number (TON) values for two pipes were similar to new pipes even after 1 year in use. Ionizing radiation stimulates existing signal transduction pathways involving the activation of epidermal growth factor receptor and ERBB-3, and changes of intracellular calcium in A431 human squamous carcinoma cells. GPR61-deficient mice exhibited obesity associated with hyperphagia.

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Towards a better understanding of the links between stressors, hazard assessment and ecosystem services under water scarcity. Poliomyelitis, pathogenesis and prophylaxis with use of gamma globulin. Long-term effects of postovulatory aging of mouse oocytes on offspring: a two-generational study. Muscle fatigue is an interesting condition to analyze the neural adjustments in antagonist muscle activity and to gain more insights into the control mechanisms of coactivation. Along with the challenge, ITS offer a unique opportunity to contribute to the Toxicology of the 21st century by providing frameworks and tools to actually implement 21st century toxicology data in the chemical management and decision making processes. Calcium pyrophosphate dihydrate crystal deposition disease of the knee simulating spontaneous osteonecrosis. The double immunodiffusion technique was utilized for the determination of Candida antibodies. The functionality of porous three-dimensional (3D) magnesium phosphate (MgP) scaffold was investigated for the development of a novel protein delivery system and biomimetic bone tissue engineering scaffold.

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Left ventricle dysfunction and co-morbidities are responsible for a large number of complications after coronary artery bypass graft (CABG) surgery. Changes of anterior maxillary alveolar bone thickness following incisor proclination and extrusion. There may be peripheral fatigue factors not reflected in the electromyographic activity. Recent cigarette abstinence, however, is negatively associated with e-cigarette use. In all cases, fracture was found to be of a ductile nature, thus implicating cyclic fatigue as a major cause of failure and necessitating further analyses and setting of standards in this area. Sperm maturation, fluid transport, and secretion and absorption of protein in the epididymis of the echidna, Tachyglossus aculeatus.

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The effect of tracheostomy on outcome in intensive care unit patients. Long work hours is associated with suboptimal glycemic control among US workers with diabetes. These studies reveal disparate effects of T on the terminal fields of the two DA systems. Administration of WYC02-9 in a nude mouse DU145 xenograft model further identified the parlodel drug anti-cancer activity of WYC02-9. Numbers and types of major and minor complications were assessed.

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Spectrum of cardiac disease in maternity in a low-resource cohort in South Africa. Complex role of TNF variants in psoriatic arthritis and treatment response to anti-TNF therapy: evidence and concepts. Identification of the soluble starch synthase activities of maize endosperm. Twenty-four children with infantile or juvenile idiopathic scoliosis had their spines corrected and solidly fused posteriorly before the age of eleven years. The study included 143 triplet pregnancies that underwent reduction to twins over a 10-year period at a single center. We speculate that establishing risk thresholds for neurotoxicity by using newer methods for measuring Bf in minimally diluted serum samples will improve the sensitivity and specificity of serum indicators for treating hyperbilirubinemia, thus reducing unnecessary aggressive intervention and associated cost and morbidity. Cochlear gene therapy has been successfully used in the treatment of neurosensory hearing loss. Future prospective studies should evaluate whether this classification improves clinical decision making. Results of the intervention showed a decrease in self-injury and an increase in bite acceptance.

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