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Anazac (Tramadol)

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Anazac is used to relieve moderate to moderately severe pain. Anazac is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the brain and nervous system respond to pain.

Other names for this medication:
Acupain, Acuvin, Anatram, Atdol, Avdol, Cadol, Combitram, Contradoc, Cormadol, Cosdol, Cradol, Doleira, Dolfre, Dolodol, Dolotram, Dolriz, Dolstar, Oshdol, Painex, Paxmax, Redimol, Rybix, Ryzolt, Sedate, Servodol, Tacil, Takol, Tandam, Traceta, Tragesic, Tramabit, Tramache, Tramacip, Tramatas, Tramazol, Tramot, Trapain, Trapidol, Tremtec, Tridol, Trofel, Trydol, Tryme, Veeradol, Vintram

Similar Products:
Depakote, Acticin, Albenza, Medrol, Sildigra, Rhinocort, Urispas, Sinatrim, Ranex, Filet, Dulok, Pregmate, Cetridoc, Artaz, Clarix, Cenforce, Nerwita,

Also known as: Tramadol


Anazac (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

Anazac is used to treat moderate to severe pain in adults.

The extended-release form of tramadol (Anazac ER) is for around-the-clock treatment of pain. Anazac ER is not for use on an as-needed basis for pain.


Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Anazac: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Anazac is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Anazac dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw the medicine away after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Anazac are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Anazac ER if you are allergic to it, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Anazac ER should not be given to a child younger than 12 years old. Anazac ER should not be given to anyone younger than 18 years old.

Do not give Anazac ER to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Anazac ER. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

Tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use Anazac ER during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using Anazac ER if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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We observed the emergence of a new PRRSV population, identified by a single nucleotide change in the ectodomain. In doing so, we have refined and developed experimental designs to analyze tRNA function. Complete evaluation was performed to rule out other infertility causes. Western blot analysis of tissue extracts from the normal and hyperplastic transition zone shows that FGF9 is present at two to threefold higher levels in the hyperplastic transition zone. Ultrasound diagnosis earlier in the natural history of the condition has meant that more conservative treatment options can be considered and implemented in clinically stable women. In addition, intima medial thickness (IMT) was measured in the left and right carotid arteries. Stathmin was identified as an endometriosis-related protein by comparative proteomics in our previous study. Some noninvasive insights into the pathophysiology of TBI are possible using magnetic resonance imaging (MRI), computed tomography (CT), and many other forms of imaging as well. Role of dronedarone in atrial fibrillation: more questions than answers. Effect of strong magnetic fields on active transport in the choroid plexus.

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Changes in the pulmonary circulation during nasal stimulation in spontaneously breathing rabbits did not differ significantly from changes in artifically ventilated animals. We recently reported expression of multiple muscarinic receptors in human lung fibroblasts and demonstrated muscarinic receptor-induced, G(i)-mediated proliferation in these cells. In this case-control analysis of women with an early pregnancy diagnosis of GDM, we estimated the association between an early pregnancy A1C and subsequent diagnosis of DM. The present work was based on a method previously published to detect AP phytoplasma. The similar pattern of change observed for MEP and intermuscular coherence may indicate similar mechanisms of action, although this cannot be assumed without further investigation. Contingent negative variation elicited by electrical taste stimulation. Milk SCC, NAGase activity, and trypsin inhibitor capacity were also monitored.

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This represents the first documentation of tumor control via EBRT, ocular FMH, and a combination of these treatment modalities in this murine transgenic retinoblastoma model. Twenty-four h after dosing, the brains of 5 animals from each dose group were examined for NTE and AChE activities. To determine if patients with pathological, medical renal disease, defined as evidence of pathological abnormalities indicative of renal damage in the non-neoplastic partial nephrectomy specimens, have worsened functional outcomes following robot-assisted partial nephrectomy. One definite and 3 probable PBC diagnosis could be made in 4 cases including 3 females and 1 male after half a year. RNAs labeled in vitro by polymerase from leaves infected with broadbean mottle virus. Human papillomavirus is rarely present vaginally in virginal women, even with the use of tampons or digital penetration. The possible harmful effect of nitrous oxide in cerebral ischaemia is debated. After stent implantation, Guglielmi detachable coil embolization was performed. Studies with androgens alone and androgens plus estrogens in the natural menopause are ongoing at present. Skeletal survey revealed epiphyseal and metaphyseal irregularities.

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The Ultrasonix 500RP: a commercial ultrasound research interface. Measles outbreak in the Barcelona Region of Catalonia, Spain, October 2006 to February 2007. In comparison, 10 of the remaining 26 high risk infants without symptoms of allergy did have such antibodies. Three newborn girls who eventually died had been suffering from a skeletal dysplasia and a serious bronchopulmonary dysplasia, serious intractable deterioration after surgery for necrotising enterocolitis, and trisomy 18 respectively. Ad vector-based influenza vaccines for pandemic preparedness are under development to meet global vaccine demand. To rapidly detect such mutations, we developed a long RT-PCR method. Synthesis and characterization of pH-responsive N-naphthyl-N,O-succinyl chitosan micelles for oral meloxicam delivery.

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As LH- and cAMP-promoted StAR transcription requires the induction of Nur77, product of Nr4a1 gene, we analyzed the roles of ERK1/2 and MKP-1 in 8Br-cAMP-mediated Nr4a1 expression in MA-10 Leydig cells. Taken together, our results indicate that CaLOX1 plays a crucial role in plant stress responses by modulating the expression of ABA- and stress-responsive marker genes, lipid peroxidation and H2O2 production. Upper airway infection and pediatric anesthesia: how is the evidence based?. In addition, relevant articles were cross-referenced to screen for additional information. A comparative study of primary secondary amino (PSA) and multi-walled carbon nanotubes (MWCNTs) as QuEChERS absorbents for the rapid determination of diazepam and its major metabolites in fish samples by high-performance liquid chromatography-electrospray ionisation-tandem mass spectrometry. NK cell activation in visceral leishmaniasis requires TLR9, myeloid DCs, and IL-12, but is independent of plasmacytoid DCs. Ten experienced retinal specialists independently reviewed the angiograms (presented in random order without the corresponding color fundus photographs) and rendered a diagnosis.

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Hemoglobin-induced lung vascular oxidation, inflammation, and remodeling contribute to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeated-dose haptoglobin administration. Phase transitions in highly asymmetric binary hard-sphere fluids: Fluid-fluid binodal from a two-component mixture theory. Effects of reduced rates of two insecticides on enzyme activity and mortality of an aphid and its lacewing predator. Furthermore, there is some evidence that the safety, efficacy and feasibility is good in daily routine practice. The metabolic and structural findings are consistent with progressive neuroaxonal loss in the WM accompanied by astrocytic proliferation-histopathological changes known to occur in HSP-TCC. The relative contribution of recombination, as opposed to de novo mutation, in the generation of new bacterial genotypes varies among bacterial populations and, as this contribution increases, the clonality of a given population decreases. Our study identified no benefit from cisapride therapy in babies with gastroschisis and also there was no benefit from elective Caesarean section for babies with antenatal diagnosis of gastroschisis. Recent nanomechanical tests on submicron metal columns and wires have revealed a dramatic increase in yield strength with decreasing sample size.

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Intranasal mupirocin or Polysporin Triple (PT) ointment (polymyxin B, bacitracin, gramicidin), in combination with chlorhexidine body washes, have been used for eradicating methicillin-resistant Staphylococcus aureus (MRSA), but no comparative studies have been done. The CD40, CTLA-4, thyroglobulin, TSH receptor, and PTPN22 gene quintet and its contribution to thyroid autoimmunity: back to the future. Recently, a deeper knowledge of the molecular mechanisms that control our biological clock and circadian rhythms has been achieved. We used single-pulse transcranial magnetic stimulation (TMS) to explore the temporal organization of the cortical control of memory-guided saccades in eight humans. These results provide a theoretical basis and new ideas for efficient design and development of new antifungal agents. This lack of effective therapeutic strategies has even questioned the validity of the process as a single entity.

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Infants receiving acidified liquid human milk fortifier were more likely to develop metabolic acidosis and to be switched off HMF than those who received powdered HMF. Based on this research, the team developed guidelines and a provider education program. Nurse-administered propofol sedation: a review of current evidence. Science Education and the Environmental Mutagen Society: a time to focus on students. Urinary levels of nitrate, nitrite, N-nitroso-2-methylthiazolidine-4-carboxylic acid (NMTCA), N-nitrosoproline (NPRO), N-nitrososarcosine (NSAR), N-nitrosothiazolidine-4-carboxylic acid (NTCA), as well as serum H. Molecular cloning and characterization of the gene encoding rat submandibular gland apomucin, Mucsmg.

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Effect of nesiritide infusion duration on renal function in acutely glucophage 1000 mg price in turkey decompensated heart failure patients. Insertion of this A/T-rich cassette increased gene expression in all cases tested. NT measurements were converted to multiples of the median (MoM(NT)) using a previously reported linear regression analysis. Survival, health-related quality of life as well as direct medical costs for in- and outpatient treatment from a health care system perspective were determined. Cytotoxic T-lymphocyte response induced by a V3 loop synthetic peptide from an African HIV-1 isolate is cross-reactive against HIV-1 strains from North America/Europe region. The etiologic agents and the probability of coinfection are discussed.

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