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Amtim (Amlodipine)
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Amtim

Amtim is in a class of medications called calcium channel blockers. It lowers blood pressure by relaxing the blood vessels so the heart does not have to pump as hard. It controls chest pain by increasing the supply of blood to the heart.

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Also known as: Amlodipine

Description

Amtim (amlodipine) is a calcium channel blocker that dilates (widens) blood vessels and improves blood flow.

Amtim is used to treat chest pain (angina) and other conditions caused by coronary artery disease.

Amtim is also used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.

Amlodipine is for use in adults and children who are at least 6 years old.

Dosage

Take Amtim exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended.

You may take Amtim with or without food. Take the medicine at the same time each day.

Your blood pressure will need to be checked often.

Your chest pain may become worse when you first start taking Amtim or when your dose is increased. Call your doctor if your chest pain is severe or ongoing.

If you are being treated for high blood pressure, keep using Amtim even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Your hypertension or heart condition may be treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or stop taking any of your medications without your doctor's advice. This is especially important if you also take nitroglycerin.

Amtim is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture, heat, and light.

Detailed Amtim dosage information

Overdose

If you overdose Amtim and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Amtim overdosage: fainting, dizziness, rapid heartbeat.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Amtim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Amtim if you are allergic to amlodipine.

To make sure Amtim is safe for you, tell your doctor if you have ever had:

liver disease; or a heart valve problem called aortic stenosis.

Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether Amtim will harm an unborn baby. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating hypertension may outweigh any risks to the baby.

Amlodipine can pass into breast milk, but effects on the nursing baby are not known. Tell your doctor if you are breastfeeding.

Amtim is not approved for use by anyone younger than 6 years old.

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Activation of the ionotropic P2RX7 nucleotide receptor by extracellular ATP has been implicated in modulating inflammatory disease progression. First-trimester chromosome diagnosis by lavage of the uterine cavity. These results suggest that one-class classification may be a promising approach to help in the detection of disease conditions. Nonetheless, in the clinical setting of reduced renal perfusion as seen in various forms of cardio-renal disease, dehydration, and the aging kidney, the adequacy of renal prostaglandin production mediated predominantly by cyclooxygenase-1 (COX-1) and, potentially, by COX-2 enzyme activity becomes of major significance in the activation of compensatory renal hemodynamics. This behavior is not observed in other conditions associated with increased serum concentrations of uric acid, hypoxanthine, and xanthine. Pilot study evaluating the potential efficacy and safety of triple antiviral therapy in interferon-alpha non-responders. To study the signal transduction pathway induced by argipressin (4-8) (AVP4-8) in rat hippocampus. Pretreatment antibiotic resistance in Helicobacter pylori infection: results of three randomized controlled studies. A plant homeodomain (PHD) is much more prevalent than previously suspected. Despite numerous studies showing neurotrophic and neuroprotective effects of estrogen in animal models, the long-term effects of estrogen use on brain morphology in older women are not known.

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Agmatine binds to several target receptors in the brain and has been proposed as a novel neuromodulator. We tested the extent to which the Rvs167p protein domains rescued phenotypes associated with deletion of RVS167: salt sensitivity, random budding, and endocytosis and sporulation defects. Mechanical effects of respiration and stepping on systolic arterial pressure variability during treadmill exercise. Relationship of neuropeptides to nitrergic innervation of the canine laryngeal glands. In Saccharomyces cerevisiae, we combinatorially replace all regulatory network promoters by their counterparts from Saccharomyces paradoxus, measure the resulting network inducibility profiles, and model the results.

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Unlike other PI3Ks, the Vps34 lipid kinase specifically utilizes phosphatidylinositol as a substrate, producing the single lipid product PtdIns3P. Cutting balloon in reverse CART technique for recanalization of chronic coronary total occlusion. Evidenced-Based Medicine (EBM) and the Cochrane Collaboration (CC) provide a source of tools and ideas for doing so, as well as a roster of colleagues who share this interest. The glycoproteins and the specific receptors responsible for adenovirus adsorption to the membranes were readily extracted into solutions containing low concentrations of Triton X-100. This appears to define a structural role for Ndel17, as it can bind a high-molecular mass complex in cytosol. However, the relations between TSP-1 and VEGF in MPM merit further investigation for possible innovative therapeutic interventions. Moderate to weak hybridization signal is also present in several other hypothalamic nuclei, specific layers of the neocortex, periaqueductal gray, and several nuclei within the pons and medulla, including locus coeruleus, lateral parabrachial, motor trigeminal, pontine reticular, hypoglossal, vestibular complex, ambiguus, and facial and lateral reticular nuclei. All static fusimotor fibres produced at least 1 to 1 driving of primary afferent discharge at 50/s if the muscle length was adjusted to optimize conditions for driving.

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Effects of network development on attitudes towards work and well-being at work among health care staff in northern Finland. The expression of Nogo-A in ipsilateral ventroposterior nucleus (VPN) of the thalamus in RHRSP was observed at 1, 2 and 4 weeks after distal MCAO. To evaluate the outcomes of anterior hybrid decompression and segmental fixation for adjacent three-level cervical spondylosis. Apoptosis was induced in S-phase-arrested HeLa cells by staurosporine, caffeine, 6-dimethylaminopurine, and okadaic acid, agents that activate M-phase-promoting factor and induce premature mitosis in similarly treated hamster cell lines. In the absence of manure colloids, bacterial attachment to soil, silt, and clay particles was much higher than the attachment to sand particles having no organic coating. A biological affinities study based on frequencies of cranial nonmetric traits in skeletal samples from three cemeteries at predynastic Naqada, Egypt, confirms the results of a recent nonmetric dental morphological analysis. In normal articular cartilage, C1s was negative in staining with both PG11 and M241.

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GM1 dynamics as a marker for membrane changes associated with the process of capacitation in murine and bovine spermatozoa. Neck myoclonus is common during REM sleep and more frequent in younger individuals. Despite the low frequency of clinical breakthroughs with noninvasive protein drug delivery this far, it remains an active research area with renewed interest not only due to its improved therapeutic potential, but also due to the attractive commercial outcomes it offers. Influence of taxonomic relatedness and chemical mode of action in acute interspecies estimation models for aquatic species. CIT analysis, which is insensitive to surface pressure, provides a direct measure of the extensional stress-strain behavior of an interfacial film without the need to assume a mechanical model (e.g., viscoelastic), and without requiring difficult-to-test assumptions regarding low-strain material linearity. After combined cholinergic and beta-adrenergic inhibition, all exercised rats had slower heart rates and higher peak stroke volume than respectively sedentary controls.

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We studied on the presumption that the phenomenon is due to heterogeneity in molecular weight of alpha 2M. Tumoral calcinosis is a rare, benign disease that commonly affects the African blacks. Uncleaved holoreceptor species included a nonglycosylated form of apparent molecular mass 85 kDa and two glycosylated forms of approximately 110 and 120 kDa. Interleukin-6 (IL-6), leukemia inhibitory factor, oncostatin M, IL-11, and ciliary neurotropic factor are a family of cytokines and neuronal differentiation factors which bind to composite plasma membrane receptors sharing the signal transducing subunit gp130. A symposium on the chronic pain syndrome in problem low back cases. Clinical examination and ultrasound assessment of PVR should be performed in all women presenting with prolapse and UTI. Targeting CD147 regulates hepatocyte MMP production both in-vitro and in-vivo, with the net result being reduced fibrotic matrix turnover in-vivo.

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Concentration-dependent inhibitory and stimulating effects of amphiphilic ammonium salts upon photosynthetic activity of spinach chloroplasts. In radiotherapy of the thoracic region, the lung is one of the most critical dose-limiting organs. In contrast, NKCC1, KCC2, STK39, WNK1, and WNK4 transcript levels did not differ between subject groups. In the present study, GDF5 was found to be differentially regulated during adipocyte differentiation. In particular, the interchromatin granule clusters, or IGCs, become colocalized with RNA polymerase II (RNAP II) upon treatment with transcription inhibitors.

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Considering the relatively high conversion rate in cases of acute cholecystitis, it is necessary to pre-operatively estimate the chance of successful laparoscopic cholecystectomy. An oxidative environment promotes growth of Mycobacterium abscessus. The spreader is indispensible in lung transplantation surgery performed especially through minimally invasive (bilateral limited anterolateral thoracotomies with intact sternum) approach. Relation of obesity and gender to left ventricular hypertrophy in normotensive and hypertensive adults. Rectal hypersecreating willous tumor with hydroelectrolytic depletion syndrome. A diagnosis of abdominal histoplasmosis was made based on the gross, microscopic, and immunohistochemical findings. Both the time-resolved emission spectrum and time-resolved area normalized emission spectrum infer the generation of excited state zwitterionic form of TPT from the excited state cationic form of TPT, as a result of ESPT process from the -OH group of TPT to the nearby water molecule. This paper introduces a conceptual framework to examine how individuals and households fulfill daily caloric needs and the aggregate effects on resource availability and consumption.

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Development and testing of a European Union-wide farm-level carbon calculator. Physicians should thus be aware of the possibility that a tooth, which has undergone dental restoration, may cause odontogenic maxillary sinusitis. The cumulative variance of the dependent variable explained by the PLS components and determined by cross-validation (Q(2)cum), for the optimal models, is 0.637, indicating that the model has good predictive ability and robustness, and could be used to estimate Rair values of OCP. A dual-cure composite applied in bulk on acid etched enamel obtained acceptable marginal adaptation results, and may be an alternative technique for the restoration of class II cavities. Conception during the summer months was associated with an over-representation of children with ASD in this UK birth cohort. Maintaining care of NMSC in the office-based setting is more cost-efficient than utilizing ambulatory surgical centers or hospital operating rooms. AMPA receptor-mediated miniature EPSCs have heterogeneous time courses in orexin neurons. More attitudinal variables were related to future behavior compared with past behavior. Adult moyamoya disease progressing from unilateral to bilateral involvement .

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Vertical distribution of nitrifying populations in bacterial biofilms from a full-scale nitrifying trickling filter. Genome structure and expression of the ev/J family of avian endogenous viruses. Silica gels, although not suitable for intravenous perfusion, are inert and optically transparent, thus allowing a full characterization of the functional and structural properties of encapsulated hemoglobin by spectroscopic techniques. Reduction cystoplasty is a useful procedure to treat a large, poorly functioning bladder in boys with prune belly syndrome who are candidates for urinary tract reconstruction. This article reports on the use of transition groups to improve the linkages between inpatient and outpatient alcoholism treatment. EDTA blood samples drawn at admission were analyzed using automated hematology system, and BNP concentration was measured using a fluorescence immunoassay. Investigating rare events with nonequilibrium work measurements.

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IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells. Further characterization of this large, granule-filled cell by electron microscopy demonstrates features in common with the Paneth cell of mammalian cymbalta generic cost small intestine, previously identified as a site of expression of antimicrobial peptide genes of the defensin family in mouse and human. The alternative sigma factor RpoS and the outer membrane lipoprotein OspC, which are induced by increased temperature and required for mammalian infection, are not upregulated in the hfq mutant. Effects of age and passage difficulty on listening-rate preferences for time-altered speech. Lower urinary tract symptoms in men, over age of 50 years is suggestive of benign prostatic enlargement (BPE). Effect of cigarette smoking on epithelial ovarian cancer survival. The aim of the present study was to investigate the hepatoprotective effect of green tea extract (GTE) against the hepatic fibrosis induced by carbon tetrachloride (CCl4), ethanol, and dual exposure to CCl4 plus ethanol in rats.

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Training program for rehabilitation of patients with internal diseases. Subtotal thrombosis of the juxta-ductal thoracic aorta in a premature 36-week-old infant. Non-invasive determination of tumor oxygen tension and local variation with growth. The aim of the present study was to determine the success rate after 12 months of follow-up in a series of cases in which chemo-mechanical caries removal (CMCR) was performed with Papacarie(TM), followed by restoration with glass ionomer cement. Structure-based comparisons can detect remote homologs but most methods for doing so are too expensive to apply at a large scale over structural databases of proteins. Penicillium brevicompactum is a ubiquitous fungal species that contaminates diverse substrates and commodities and produces an array of metabolites toxic to human and animals. Serial monitoring, BL updating, and cross-calibration techniques were developed and evaluated. Exogenous GSH provided protection from all toxic compounds suggesting that the toxic species is electrophilic.

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We showed previously that SLP-76 is required for neutrophil function in vitro, including integrin-induced adhesion and production of reactive oxygen intermediates, and to a lesser extent, FcgammaR-induced calcium flux and reactive oxygen intermediate production. This, and other biological features, necessitated the proposal of new morphological terms, and they are discussed here. In order to substantiate a possible role of this channel in early development in anurans, we have detailed the kinetics of the expression and the localization of the alpha 1 subunit of L-type calcium channel in the early stages of Xenopus laevis embryogenesis using immunological techniques. Recurrent laryngeal or vagus nerve injuries in the mediastinum are repaired rarely because of technical difficulties. On the other hand, the new protease inhibitors have some similarities to the soybean inhibitor described by Kunitz, and to ovomucoid. Mosquitoes were caught at different localities in the Amazon region. In such cases with negative cytology result, for cervical cancer prevention, the electrocoagulation or electro-conisation or other destructive operations are routinely used. Cloning and expression of the cDNA encoding rat granulocyte colony-stimulating factor. Amongst 300 examinations of the shoulder in miners working with compressed air, degenerative changes were found in 44.

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The implementation of an effective eye-care programme remains a priority in the Limbe urban area. Successes and future outlook for microfluidics-based cardiovascular drug discovery. Five patients with buccal gingival recession (4 to 6 mm) underwent surgical treatment consisting of a guided tissue regeneration procedure associated with a permethrin 5 cream 60gm cost free gingival graft. Blindness as a consequence of a paraneoplastic syndrome in a woman with clear cell carcinoma of the ovary. Arachnoiditis ossificans with progressive syringomyelia and spinal arachnoid cyst. Interaction of bumps on adjacent membranes lead to true membrane contact and form bridges between the membranes as microextension, combining both membranes into a topologically single structure.

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Better understanding of the mechanisms involved in docosahexaenoic acid (DHA) transfer to the neonate may contribute to improve dietary support for infants born prematurely to mothers with placental lipid transport disorders. The segregation ratio of a subset of six RAPD markers in five other individuals from the same population confirmed their genetic nature. Expression of rat aspartyl-tRNA synthetase in Saccharomyces cerevisiae. A tapered hollow waveguide that can focus a laser beam into a small beam spot is proposed for medical and dental applications. The size distribution of thyroid follicles in single thyroid glands, a peculiar problem of particle size distribution in stereology. Results of the administration of large doses of corticoids to patients in endotoxic shock. Such study invites the investigation of those who do not succeed in changing behaviour, as against the study of those who do.

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