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Amizep (Amitriptyline)

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Amizep is an antidepressant medication that is sometimes prescribed off-label to manage chronic back pain. It is one of the drugs in a class of drugs known as tricyclic antidepressants. Amizep is not a narcotic (opioid) drug, and there is not usually an addiction risk with the medication.

Other names for this medication:
Abamax, Amiclozor, Amidez, Amiline, Amimax, Amitrac, Amitrim, Amitriptyline, Amitwix, Amity, Amixide, Amline, Amsha, Amtipax, Amtran, Axtrip, Bluneel, Cotrip, Crypton, Eliwel, Endep, Eptanol, Kamitrin, Libotryp, Librodep, Mitrip, Mitryp, Normaline, Raitrip, Ronet, Tablin, Teedep, Tridep, Triplent

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Also known as: Amitriptyline


Amizep (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

Amizep is a prescription medicine used to treat symptoms of depression.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amizep dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amizep are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Amizep if you are allergic to Amizep components. Do not take Amizep if you are pregnant, planning to become pregnant, or are breast-feeding. Be careful with Amizep if you suffer from or have a history of a history of heart attack, stroke, bipolar disorder (manic-depression), schizophrenia or other mental illness, diabetes, overactive thyroid, glaucoma, problems with urination, heart disease, seizures. Be careful with Amizep if you are taking guanethidine (Ismelin), disulfiram (Antabuse), heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), quinidine (Cardioquin, Quinidex, Quinaglute), cimetidine (Tagamet). Avoid alcohol. Be careful! Taking Amizep you can become suicidal. Be careful when you are driving or operating machinery. Be careful with Amizep if you are going to have a surgery. It can be dangerous to stop Amizep taking suddenly.

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Practices are heavily influenced by the specific dynamic clinical characteristics of patients and may be further modified by clinician specialty and seniority, the use of protocols and advanced neurological monitoring. Our results demonstrate that omeprazole inhibits giardial triosephosphate isomerase in a species-specific manner through interaction with cysteine at position 222. We assessed PTSD and trauma reminders in 58 school-age children three years after the terrorist attack in Beslan, Russia in 2004, as well as their association with degree of exposure, psychological distress and coping. The dsDNA-AuNPs undergo rapid aggregation in a medium of high ionic strength, whereas particles having a single-base protrusion at the outermost surface disperse stably, allowing detection of a single-base difference in length by color changes. Methods of equine identification including signalment, blood typing tattooing and freeze marking are discussed. We examined the cell cycle checkpoint response of human mammary epithelial cells (HMEC) and their isogenic fibroblast counterparts to ionizing (IR) and ultraviolet (UV) radiation, two genotoxic agents whose DNA damage response pathways involve p53. A prospective cohort study of HIV-infected adults who met expanded clinical case definitions for smear-negative PTB and EPTB. Once-weekly bisphosphonate doses have safety and tolerability profiles as good as daily doses and are comparable with the placebo.

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Neonatal hyperbilirubinemia and childhood allergic diseases: a systematic review. Endogenous activation of metabotropic glutamate receptors in neocortical development causes neuronal calcium oscillations. The main outcome measure was amelioration of symptoms of neuropathy. The results recommend not to use a lower doses in order to assure a permanently efficient penicillin concentration. The effect of n-acetylcysteine on hepatic histomorphology during hypothermic preservation. For both syndromes, the etiologies are still unclear in many facets. This value can be decreased in the future using a smaller irradiation field and decreased time for examination in VF in the future.

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To better understand the possibilities of antiangiogenic tumor therapy and to assess possible side effects, we investigated the effect of tumour necrosis factor (TNF)-alpha and curcumin on the expression of vascular endothelial growth factor (VEGF) in U937 and Raji cell lines and their effect on angiogenesis in a human umbilical vein endothelial cell (HUVECs)-derived cell line (ECV304), and also the relationship between Notch1 and VEGF. Next, we examined the neurotoxic host factors using co-culture system with macrophage-tropic HIV-1-infected macrophages as followings: Target brain cells are murine neuron/glia mixed culture, murine neurospehre-forming culture and rat brain hippocampus slice culture. The continuous increase of pressure drives the formation of a tetragonally distorted VII structure with the space group I4mm, rather than a cubic Pn3m phase in bulk ice. The prevalence of intellectual disability across all 52 studies included in the meta-analysis was 10.37/1000 population. To our knowledge this is the first global surveillance system for chemical incidents of potential international concern. Potential long-term benefits of acute hypothermia after spinal cord injury: assessments with somatosensory-evoked potentials. In 1905 Barany analyzed the nystagmus that appears during the irrigation of the ear with cold and hot water, justifying the phenomenon due to convectives currents in the horizontal semicircular canal. Phenotypic variability and pleomorphism due to culturing on artificial media is common among this group of organisms and has led to the description of numerous species. In the hospital that adopted the protocol, almost five times more black than white newborns were reported during the study period. Although further wide-scale research is warranted, it is becoming increasingly clear that Gadd45s are highly relevant to aging, age-related diseases (ARDs) and to the control of life span, suggesting them as potential therapeutic targets in ARDs and pro-longevity interventions.

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The aim of this study is to evaluate the relationship between acute exacerbations and the mean platelet volume (MPV) trend in children with cystic fibrosis (CF), to predict the exacerbations. Androgen levels are significantly increased in T1D adolescents and young women treated by intensive insulin therapy. Pathology reports from VATS performed between January 1995 and July 1997 were searched for data on gross specimens revealing pulmonary nodules 3 cm or smaller. Evaluation of non-medical costs associated with visual impairment in four European countries: France, Italy, Germany and the UK. We developed a new method using two-parameter spillover correction to estimate regional MBF (rMBF) with (11)C-acetate PET in reference to MBF derived from (15)O-H2O PET. Increased Cdk activity may critically reduce licensing of origins of DNA replication, drive re-replication, or mediate overexpression of checkpoint proteins, inducing deleterious cell cycle delay. Both cuproenzymes changed during neonatal development and when dietary copper was limiting. Flexible-resource theories characterize working memory as a flexible resource that can store either a large number of low-quality representations or a small number of high-quality representations. The results showed that I/R elevated MDA levels, which were accompanied by a reduction in SOD activities and GSH levels.

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Use of next generation sequencing in head and neck squamous cell carcinomas: a review. We have demonstrated that the crowd can address the challenges of scalable ontology verification, completing not only intuitive, common-sense tasks, but also expert-level, knowledge-intensive tasks. E-2078 generalized in EKC-discriminating monkeys, but only after the largest dose (3.2 mg/kg), and only following IV administration. Our results identify the first inactivating mutation in TbetaR-I gene in a human lymphoma that renders it insensitive to growth inhibition by TGF-beta. The ventroflexion traction group (A) received the same multimodal program as group C, with added traditional ventroflexion traction.

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Cystic type I/Ir PPB has a better prognosis than type II, and type II has a better outcome than type III. Surprisingly, a normal G(s) response was seen for the B2 mutant, and the B3 mutant showed only a 6-fold decrease in agonist potency. Sub-conjunctival dislocation of posterior chamber intra-ocular lens: five years after manual, small-incision cataract surgery. Molecular and morphological comparison of two different types of Habronema amoxil dosing pediatrics muscae (Nematoda: Habronematidae) in horse. Inactivation half-time of the enzyme at 50 degrees C was 25 min.

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Diagnosis of pulmonary lymphangiectasis was confirmed by biopsy. The semiclassical laser equations for such structures are simulated with three different theoretical techniques: exact finite-difference time-domain calculations, an steady-state ab-initio laser theory and a semi-analytical coupled-mode formalism. Conventional and echo-planar DW MRI was performed in 2 patients in the active phase and 6 patients in the recovery phase (1 to 8 hours after cessation of anterograde memory dysfunction) of spontaneously occurring TGA. Little is known about the scholarly production of faculty members who teach in respiratory care programs. Humans are hardwired to enjoy food, and our bodies voraciously extract and store energy from food as if each meal was the last. Cyclodextrin-functionalized silica nanoparticles with dendrimer-like spacers for enantioselective capillary electrochromatography. MK-STYX was found to localize to the mitochondria but is neither released from the mitochondria upon apoptotic stress nor proximal to the machinery currently known to control MOMP, indicating that MK-STYX regulates MOMP using a distinct mechanism. Furthermore, a new nonpeptide AT2R agonist has been developed, with potential future therapeutic applications in hypertensive conditions. In serum, we determined the catalytic activity of Alanine Aminotransferase, Aspartate Aminotransferase, Lacticate Dehydrogenase, and Ornithine Carbamoyltransferase.

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The results indicate that there is a dissociation between tracheal dimensions and anatomic dead space as well as between airway size and lung size, suggesting that dysanapsis is a general phenomenon. The doctor, the patient, and the system: reflections on education for clinical careers. The universally valid indicators should combine several parameters to supply complementary information. To examine the efficacy and safety of short-term and long-term use of antidepressants in the treatment of bipolar disorder. Patients with LS underwent genotyping for the whole genome of mitochondrial DNA and SURF1 mutations. AIDS in the San Francisco bay area: the experience of an IPA model HMO. Subjects were evaluated for depression symptoms and DSM-IV major and minor depression syndromes. In this paper, a novel data-driven robust approximate optimal tracking control scheme is proposed for unknown general nonlinear systems by using the adaptive dynamic programming (ADP) method. The structure functions and radial distribution functions obtained from energy-dispersive X-ray diffraction spectra, recorded newly for BAN and for the first time for 4-MeOBAN and 4-HOBAN, are compared with the corresponding quantities calculated from MD trajectories, to access information on the morphology of these liquids. Vascular smooth muscle (VSM) cells constitute the main structural components of tunica media.

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Aerial web-weaving spiders display a wide variety of foraging behaviors that can be tied to the evolution of one family of proteins, the silks. Three-factor anonymous authentication and key agreement scheme for Telecare Medicine Information Systems. We describe a convenient, versatile and safe method for preparing bacterial DNA for ribotyping analysis. He had no history of hypertension or any other risk factor for aortic dissection. Protein extravasation and cellular uptake after high-dose human-albumin treatment of transient focal cerebral ischemia in rats. Follow-up at 6 months revealed a low level of residual FVIII inhibitor activity with normal coagulation functions safe zofran dose during pregnancy . Treatment of experimental status epilepticus in immature rats: dissociation between anticonvulsant and antiepileptogenic effects. Our research suggested that the site be a microsatellite of single nucleotide-repeated sequence. Two new labdane-type diterpenes from the wood of Cunninghamia konishii. The purpose of this study was to analyze orthopedics problems caused by type I primary hyperoxaluria before and after liver and kidney transplantation.

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Before and after the study, of the proportion of new patients attending Melbourne Sexual Health Centre from mid-2004 to mid-2011, diagnosed with genital warts (GW) by risk group. The effects of polyphloretinphosphate on the ascorbic acid depleting activity of ACTH. These nanospheres formed by poly(D,L-lactic/glycolic acid) (PLGA) or poly(D,L-lactic acid) (PLA), biodegradability and biocompatibility polymer, that were encapsulated betamethasone phosphate and zinc. Characteristics of the SG and TTO may make them inappropriate for HU assessment and CEA among RA patients. Publishing opportunities for nurses: a comparison of 65 journals. Antibiotics have the potential to cause allergic contact dermatitis and increase drug resistance and may not be necessary for the treatment of clean surgical wounds. Infections with herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2), both alpha herpesviruses, are highly prevalent worldwide.

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