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Amifru (Spironolactone)

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Amifru is a potassium-sparing diuretic (water pill) that makes you urinate more without lowering the amount of potassium in your body. It works in your kidneys to remove extra water and sodium, which helps lower the amount of fluid in your blood vessels and other areas of your body.

Other names for this medication:
Aldostix, Amifru, Aquamide, Dyamide, Dytor, Fruselac, Frusis, Lactone, Lasilactone, Metolactone, Spilactone, Spiromide, Spironolactone, Spirotic, Torlactone, Tormax, Torsid, Zator

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Also known as: Spironolactone


Amifru (spironolactone) is a potassium-sparing diuretic (water pill) that prevents your body from absorbing too much salt and keeps your potassium levels from getting too low.

Amifru is used to treat heart failure, high blood pressure (hypertension), or hypokalemia (low potassium levels in the blood).

Amifru also treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney disorder called nephrotic syndrome.

Amifru is also used to diagnose or treat a condition in which you have too much aldosterone in your body. Aldosterone is a hormone produced by your adrenal glands to help regulate the salt and water balance in your body.


Usual Adult Dose of Amifru for Edema:

25 to 200 mg orally per day in single or divided doses

Usual Adult Dose of Amifru for Hypertension:

Initial dose: 50 to 100 mg orally per day in single or divided doses

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 25 mg orally once a day assuming serum potassium is less than or equal to 5 mEq/L and serum creatinine is less than or equal to 2.5 mg/dL

Usual Adult Dose for Primary Hyperaldosteronism:

Diagnostic dose:

Usual Adult Dose for Hypokalemia:

25 to 100 mg orally per day

Detailed Amifru dosage information


If you overdose Generic Amifru and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Amifru overdosage: diarrhea, vomiting, nausea, red skin rash, loss of energy, slow heartbeat, weakness in legs, feeling drowsy, confusion.


Store below 25 degrees C (77 degrees F). Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amifru are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Amifru if you are allergic to spironolactone, or if you have:

Addison's disease (an adrenal gland disorder); high levels of potassium in your blood (hyperkalemia); if you are unable to urinate; or if you are also taking eplerenone.

To make sure Amifru is safe for you, tell your doctor if you have:

an electrolyte imbalance (such as low levels of calcium, magnesium, or sodium in your blood); kidney disease; liver disease; or heart disease.

Tell your doctor if you are pregnant or plan to become pregnant. Having congestive heart failure, cirrhosis, or uncontrolled high blood pressure during pregnancy may lead to medical problems in the mother or the baby. Your doctor should decide whether you take Amifru if you are pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

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