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Amebidal (Metronidazole)

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Amebidal belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

Other names for this medication:
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Also known as: Metronidazole


Amebidal (metronidazole) is an antibiotic that is used to treat bacterial infections of the vagina, stomach, liver, skin, joints, brain and spinal cord, lungs, heart, or bloodstream.

Amebidal is also used to treat trichomoniasis, a sexually transmitted disease caused by a parasite. Usually both sexual partners are treated at the same time, even if one has no symptoms.

Do not use Amebidal to treat any condition that has not been checked by your doctor.


Amebidal 250-mg tablets are round, blue, film coated, with SEARLE and 1831 debossed on one side and Amebidal and 250 on the other side; bottles of 50, 100, and 2,500. Amebidal 500-mg tablets are oblong, blue, film coated, with Amebidal debossed on one side and 500 on the other side; bottles of 50, 100, and 500.


Single oral doses of Amebidal, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Amebidal has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Amebidal overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.


Store below 77 degrees F (25 degrees C) and protect from light.

Side effects

The most common side effects associated with Amebidal are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Amebidal if you are allergic to metronidazole, secnidazole, or tinidazole, or if:

you recently drank alcohol; or you took disulfiram (Antabuse) within the past 14 days.

Do not take metronidazole during the first trimester of pregnancy. This medicine can harm an unborn baby. Tell your doctor if you are pregnant.

To make sure Amebidal is safe for you, tell your doctor if you have ever had:

liver disease; kidney disease (or if you are on dialysis); a heart rhythm disorder; Cockayne syndrome (a rare genetic disorder); a stomach or intestinal disease such as Crohn's disease; a blood cell disorder such as anemia (lack of red blood cells) or low white blood cell (WBC) counts; a fungal infection anywhere in your body; or a nerve disorder.

In animal studies, metronidazole caused certain types of tumors, some of which were cancerous. However, it is not known whether these effects would occur in humans. Ask your doctor about your risk.

You should not breastfeed within 24 hours after using Amebidal. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.

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