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Alpostin injection is used to treat men who have erectile dysfunction (also called sexual impotence). It belongs to a group of medicines called vasodilators that can increase blood flow by expanding blood vessels. This medicine causes an erection because it increases the blood flow to the penis.

Other names for this medication:
Alpostin, Caverject, Edex, Muse, Prostin, Vitaros

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Also known as: Alprostadil


Alpostin urethral suppository is used to treat men who have erectile dysfunction (also called sexual impotence). It belongs to a group of medicines called vasodilators that can increase blood flow by expanding blood vessels. Alpostin causes an erection because it increases the blood flow to the penis.

Alpostin should not be used as a sexual aid by men who do not have erectile dysfunction. If the medicine is not used properly, permanent damage to the penis and loss of the ability to have erections could result.

Alpostin is available only with your doctor's prescription.


A healthcare provider will give your first dose and teach you how to properly use the medication by yourself.

Follow all directions on your prescription label and read all medication guides. Use the medicine exactly as directed.

Alpostin is used only when needed. An erection should occur within 5 to 20 minutes and last up to 60 minutes.

Alpostin injection is injected into the side of the penis.

Alprostatil transurethral pellet is a very small suppository to be inserted into the opening of the penis (the urethra).

Do not use more than 2 pellets in one day. Do not use more than 3 injections per week. Wait at least 24 hours between each injection.

Ask your doctor or pharmacist if you don't understand how to use the injection.

Prepare an injection only when you are ready to give it. Call your pharmacist if the medicine looks cloudy, has changed colors, or has particles in it.

Do not reuse a needle or syringe. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.

Call your doctor if a needle breaks while you are injecting Alpostin. If you can grasp the broken end, remove the needle right away.

Your doctor should check you every 3 months to be sure Alpostin is not causing harmful effects on your penis.

Storing Alpostin:

Keep pellets in their original foil pouch in the refrigerator. You may store a pouch at cool room temperature for up to 14 days. Protect from freezing or extreme heat. Do not store in a closed automobile or in luggage while traveling. Store Alpostin injection vials at cool room temperature. The 40-microgram strength should be used within 3 months or before the expiration date on the label. After mixing a Caverject injection, keep it at room temperature and use within 24 hours.

Detailed Alpostin dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose can cause fainting, or a painful and prolonged erection.


Store at the room temperature 25°C (77°F)or below. The medication should be used within 24 hours after opening. Do not freeze it. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alpostin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Alpostin if you are allergic to any of its components or to other prostaglandins. Do not take Alpostin if you have blood problems such as sickle cell anemia or sickle cell trait, leukemia. You should not be treated with Alpostin injection if you have penile implants. Do not take Alpostin if you have penile problems, e.g. a curved or deformed penis. Do not use Alpostin if you have multiple myeloma or other bone marrow problems. Do not take Alpostin if you take other medicines for the treatment of erectile problems. Consult your doctor or health care professional immediately if the erection lasts longer than 4 hours or if it becomes painful. Alpostin is not a protector from sexually transmitted diseases or pregnancy. Avoid having unprotected sex. Do not share drug needles. Do not drive or operate machinery while taking the medication. Avoid consuming alcohol as it may worsen the medication side effects. Alpostin does not protect you and your partner from sexually transmitted diseases and pregnancy. Alpostin is not for use in women, children or newborns.

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