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Alpam (Alprazolam)

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Alpam is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alpose, Alpramax, Alpranex, Alprasan, Alprazolam, Alprop, Altin, Alzoact, Alzopax, Benzax, Cqlam, Emlol, Fluzolam, Fultop, Niravam, Normatine, Oclam, Optizole, Samitol, Selamb, Sinozol, Somnia, Tenfree, Zolam, Zolax, Zopral

Similar Products:
Lozol, Amethopterin, Periactin, Levitra, Coumadin, Glycinova, Loxapine, Indocyp, Gabapin, Wingyl, Zymycin, Cosart, Zolstatin, Flunix,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Take Alpam XR exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Alpam XR may be habit-forming and should be used only by the person it was prescribed for. Alpam XR should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not crush, chew, or break a Alpam extended-release tablet. Swallow the tablet whole. It is specially made to release alprazolam slowly in the body. Breaking the tablet would cause too much alprazolam to be released at one time.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

Your symptoms may return when you stop using Alpam XR after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using Alpam XR.

Withdrawal symptoms may include blurred vision, trouble concentrating, loss of appetite, diarrhea, muscle twitching, numbness or tingling, or increased sensations.

Do not stop using Alpam XR suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store Alpam XR at room temperature away from moisture, heat, and light. Remove any cotton from the bottle of disintegrating tablets, and keep the bottle tightly closed.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Detailed Alpam XR dosage information


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alpam XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpam XR dosage information

Side effects

The most common side effects associated with Alpam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alprazolam in the elderly. However, elderly patients are more likely to have unwanted effects (eg, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness) and kidney, liver, or lung problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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Correlating student attitudes with performance in assessing instructional programs. Thus, this current study tested the hypothesis that obesity is associated with hot flushes in mid-life women through a mechanism involving levels of total and free androgen, free estrogen, progesterone, and sex hormone binding globulin (SHBG). The incidence of post operative colic in horses requiring side-to-side jejunocaecal anastomoses was greater than those requiring end-to-end jejunojejunal anastomoses. Other factors, such as age and sleep deprivation, contribute or predispose patients to its development. Recombinant AcICK peptide (expressed in baculovirus-infected insect cells) bound directly to Beauveria bassiana and Fusarium graminearum, but not to Escherichia coli or Bacillus thuringiensis. In autoimmune diseases, an abnormal production of proinflammatory cytokines, or a reduced inhibition of their actions, may lead to an imbalance. Photo-induced conjugation of tetrazoles to modified and native proteins. Various types of axonemal abnormalities related to ICS are known, but it is unclear whether the symptom severity is related to the type of abnormality. A case of post-traumatic LASH syndrome responsive to indomethacin and melatonin (a man with a unique triad of indomethacin-responsive trigeminal autonomic cephalalgias). An open trial of adjunctive sertraline in the treatment of chronic schizophrenia.

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The expression levels of mRNAs of ion channels or transporters were evaluated from the atrial samples of sham and after a 7 hour pacing. Representation of fluctuation features in pathological knee joint vibroarthrographic signals using kernel density modeling method. However, a key obstacle to progress remains the scarcity of appropriate human cohorts available for genomic research. Whereas TLR4 recognizes viral components at the cell surface, TLR3, TLR7, TLR8, and TLR9 recognize viral nucleic acids on endosomal membrane. In order to understand the binding profile of TLF-PafF as a PDI, docking analysis was performed using monomeric protease (prepared from the dimeric crystal structure, PDB ID: 4NKK) as docking receptor. They were matched on tumour size, axillary lymph node status and years of birth and diagnosis, with four year deviation. Affected muscles had T1- and T2-values indicating a replacement of muscle fibres with fat tissue.

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A 26-year-old male presented with a trigeminal neurinoma manifesting as pathological laughter. Changes in blood and plasma composition with lower body negative pressure on the ground and in space in one subject. Similar results are obtained with other Gram-negative bacteria (Vibrio parahaemolyticus, Klebsiella pneumoniae, Pseudomonas aeruginosa) and Gram-positive bacterium (Staphylococcus aureus), and the results are also reproduced in a mouse model for urinary tract infection. 5-LO and BLT mRNA expression increased on days 16-18 of the cycle, whereas CYSLT mRNA expression increased on days 16-18 of the pregnancy. This minor hemoglobin, which arises as nonenzymatic postsynthetic addition of glucose to hemoglobin A, acts as an indicator molecule for the glucose environment over a 3-5-wk period prior to measurement. Electrophoretic characteristics and membrane receptors of lymphocytes in primary immunodeficiency diseases. These ghosts, totally free of haemoglobin, were first of all pulverised in liquid nitrogen then treated ultrasonically. (2003) to design a study for estimating dose levels of tacrolimus that will result in a certain percentage of rheumatoid arthritis patients having an ACR20 response at 6 months. Here, we present biochemical and genetic evidence that at least two contacts from the side of the TIM23 complex play an important role in TOM-TIM23 cooperation in vivo. This review addresses classical questions concerning microvascular permeabiltiy in the light of recent experimental work on intact microvascular beds, single perfused microvessels, and endothelial cell cultures.

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Correlation between low neuraminidase blood levels and a predisposition toward family-related breast cancer. In a pilot study, two independent raters applied the definition and classification in a sample of 60 surgical interventions of low, intermediate, and high complexity and evaluated practicability. Of our five patients, there were three males and two females, age ranging between 19 and 58 years (mean age 38 years). In the present study, the strength of various screw/bone constructs in femoral neck osteotomy was analyzed. Predicting Clostridium difficile toxin in hospitalized patients with antibiotic-associated diarrhea. The pre-mRNA for the rat serotonin-2C receptor (5-HT2CR) possesses four editing sites (A, B, C, and D), which undergo A-to-I nucleotide conversions that alter the signaling function of the encoded G-protein-coupled receptor. Isotretinoin is an effective and safe treatment for acne in Iranian patients. Although their clinical use is easy, several points still require further attention and research. They are known to have central nervous systems effects and are now understood to impact the regulation of gonadotropic hormones. Considerations in the protection of humans as subjects of research.

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to describe variation in utilisation of carotid endarterectomy (CEA) within two English health regions and explore relationships between use, need and proximity to services. Molecular thermodynamic modeling of specific ion effects on micellization of ionic surfactants. Measurement of microbial adhesive forces with a parallel plate flow chamber. A low molecular weight folate receptor targeted contrast agent for magnetic resonance tumor imaging. Mesenchymal stem cells (MSC) are present in the bone marrow, from where they are thought to migrate through the blood stream to the sites of injury.

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Radiotherapy of benign dermatoses: indications, practice, and results. The object of this study was to evaluate the duration of response to intermittent androgen deprivation (IAD) in patients with nonmetastatic recurrent or localized prostate cancer. The results of treatment of 468 patients, suffering goiter, were analyzed. The combined treatment of medication and psychotherapy has become the most common mode of psychiatric treatment planning in current practice. In an attempt to verify the safety and efficacy of neuracryl M, we participated in the PROVASIS Trial, a pilot study using this agent in the preoperative treatment of cerebral arteriovenous malformations (AVMs). Acute pericarditis as the first manifestation of familial Mediterranean fever: a possible relationship with idiopathic recurrent pericarditis. Also, a large number of patients seen in the PED receive no intervention. orally for 3 months in addition to oral litholysis (OLL) with ursodeoxycholic acid 500 mg/day and chenodeoxycholic acid 500 mg/day, or to Group B, who continued solely with OLL. ATP-dependent and drug-inhibited vesicle enlargement reconstituted using synthetic lipids and recombinant proteins. Reduction of substituted nitrobenzenes mediated by quinones, natural organic matter, Fe(II) complexes, and the (CH(3))(2)COH radical was examined using EA values calculated from quantum mechanics.

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Drug penetration into the aqueous humor was observed with only the non-neutralized polymer, probably occurring via the conjunctival-scleral pathway facilitated by intensified contact between the mucoadhesive polymer and the underlying bulbar conjunctiva. Mounting evidence suggests the association of immune genes with complex neuropsychiatric diseases, such as schizophrenia. Sick sinus syndrome with and without atrial fibrillation: atrial refractoriness and conduction characteristics. The low rate of ATP cleavage in the resting state of muscle is considered to result from the formation of a stable ring structure involving the two essential sulfhydryl groups on each myosin head and MgATP. Nitrogenous metabolism, vitamin provision and anthroponietric indices were inventigated in 1560 Uzbek youths (18-21 years old) with diverse alimentary status. Community Characteristics are Associated with Blood Pressure Levels in a Racially Integrated Community.

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Enhancing physiologic simulations using supervised learning on coarse mesh solutions. Although there are no clinical trials specifically designed to evaluate the better therapeutic option (ablation vs. Validation of a questionnaire method for estimating extent of menstrual blood loss in young adult women. A large basivertebral vein with its origin in the anterior bactrim prescription cost epidural space is typical of the lower thoracic and upper lumbar levels. A de novo complex chromosome rearrangement involving chromosomes 2, 3, 5, 9 and 11 detected prenatally and studied postnatally by conventional cytogenetics and molecular cytogenetic analyses. We compared 12 patients with dementia to 12 age- and gender-matched healthy subjects regarding changes in haemoglobin concentration in brain tissue while performing a verbal fluency task (VFT).

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Both collagen membranes showed similar results either when compared to each other or to the control group. Electron microscopic observation of eosinophils migrated to the thoracic cavity of Litomosoides carinii-infected mice. Problems and solutions in achieving uniform dose distribution in superficial total body electron therapy. Effect of calcium supplementation on rectal epithelial hyperproliferation in intestinal bypass subjects. The nociceptive fibers then project to the central pain-conducting pathways at the spinal trigeminal nucleus. Breath-by-breath determinations of airway occlusion pressure in the developing lamb. The HPLC method is stable, accurate, and reliable to provide a scientific basis of quality control standard for the honey-fried Radix et Rhizoma glycyrrhizae. Fungal secondary metabolites as modulators of interactions with insects and other arthropods. Patients indicated a desire for provider educational picture of norvasc medication materials on interactive media pages.

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Cloacal gland index, quantity of foam secretion, testicular weight and plasma testosterone can serve as indirect indicators of testicular activity and fertilising ability in quails. HESR1 is a downstream target of Notch in endothelial cells and could be an effector of Notch signaling in these cells. Three or four days after gene injection, the pigs underwent catheter ablation of the atrioventricular (AV) node. The introduction of longitudinally parallel V-groove technique provides an effective method for avoidance of increasing hardness, decreasing flexibility, and palpable edges after implantation.As a novel and effective technique, it is beneficial for better attachment and satisfactory outcome without causing extra expenses. A beta version of CRAWview will be freely available to academic users from Pangea Systems ( We examined the expression of TLR-9 in the liver and spleen in a murine peritonitis model (CLP mice).

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Our data clarified the potential mechanism of PDGF signaling in the lens epithelial cells, in which concerted efforts of the upstream components of PDGF receptor kinase, Src-family kinases, PI3K, Rac, and Ras proteins are required. We discuss a case report of bilateral mastoid involvement in a child with a history of otalgia unresponsive to medical therapy. Detection of putative dopamine receptors in neurites outgrowing from locust central nervous system explants using anti-idiotypic dopamine antibodies. Serum dipeptidyl peptidase-4 activity in insulin resistant patients with non-alcoholic fatty liver disease: a novel liver disease biomarker. The purpose of this case report is to document an embedded foreign object in the maxillary tuberosity region of a 6-month-old baby, mimicking features of a tumor leading to a diagnostic dilemma. Pleomorphic hyalinized angiectatic tumor of soft parts is a recently described neoplasm that most commonly affects the lower extremities.

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The expected roles of the social worker and his or her contribution to the health team are outlined. We investigated the associations between serum levels of glycated albumin (GA) or hemoglobin A1c (HbA1c) and the presence of coronary artery disease (CAD) in patients who underwent coronary computed tomography angiography (CTA). Immunologic studies in chronic lymphocytic leukemia: defective stimulation of T-cell proliferation in autologous mixed lymphocyte culture. There are three types of reflex anoxic cerebral crises: asphyxiating anoxic crises, ischemic anoxic crises and asphyxiating-ischemic anoxic crises. We revealed a relatively limited diversity in improved rye accessions, both historical and contemporary, as well as lack of correlation between clustering of improved levaquin 500 mg antibiotic accessions and geographic origin, suggesting common genetic background of rye accessions from diverse geographic regions and extensive germplasm exchange. Production, stability, and antioxidative and antimicrobial activities of two L-ascorbate analogues from phycomyces blakesleeanus: D-erythroascorbate and D-erythroascorbate glucoside. 1,4-Benzoquinone-based electrophoretic assay for glucose oxidase.

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Five years of adjuvant tamoxifen is more beneficial than 2 years in the treatment of postmenopausal women with estrogen receptor-positive, early stage, invasive breast cancer. Pentylenetetraziol-induced shock increased brain 5-hydroxyindoleacetic acid (5hiaa) concentrations and decreased 5-HT levels. To assess the prevalence of verbally and physically aggressive behaviors in dating relationships in a sample of Spanish adolescents. The lesion was excised and histology disclosed the presence of a PXA with anaplastic features. Identification of brain metabolites by magnetic resonance spectroscopy in MND/ALS. Potential involvement of BMP receptor type IB activation in a synergistic effect of chondrogenic promotion between rhTGFbeta3 and rhGDF5 or rhBMP7 in human mesenchymal stem cells. The results indicate that the optimal BCI design consistently outperforms the conventional approaches, i.e., the SC and RC paradigms. coli, Proteus mirabilis and Klebsiella spp, comparing results obtained with Etest and double disk data. Thus, an improved hygienic quality of the water course could be achieved by preventing overflows and by enhancing sewage treatment plants. A number of different leadership styles have been developed, theorised and applied to the nursing workforce over the years.

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