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Afexdine (Fexofenadine)
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Afexdine

Afexdine is an effective medical drug for allergy caused by chemical histamine which is formed in our body naturally and reacts to the external irritants causing the allergic reaction. Afexdine blocks the production and increased activity of histamine receptors as a result of which there is a reduction of the response reaction to the external irritants and the main symptoms of allergy are reduced. This drug helps to reduce cold, lacrimation, sneezing, itching, edema and other allergic symptoms.

Other names for this medication:
Afexdine, Alafex, Alernex, Alfexo, Allefast, Allofex, Arogra, Biofen, Coligra, Faydine, Fegix, Fenax, Fendosh, Fenixa, Fenofex, Ferodra, Fexidine, Fexise, Fexocare, Fexodin, Fexodine, Fexody, Fexofast, Fexofen, Fexofenadine, Fexohist, Fexokast, Fexolast, Fexon, Fexoquit, Fexoriv, Fexot, Fexotec, Fexotive, Fexotrol, Fexozide, Histakind, Histaloc, Infexo, Irmont, Montair, Montemac, Monten, Novamont, Rafen, Rhinofex, Ultigra, Xdine, Zllerfax

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Also known as: Fexofenadine

Description

Fexofenadine is an antihistamine. It is used to relieve the symptoms of hay fever (seasonal allergic rhinitis) and hives of the skin (chronic idiopathic urticaria) .

Antihistamines work by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes. Also, in some people histamine can close up the bronchial tubes (air passages of the lungs) and make breathing difficult. Histamine can also cause some people to have hives, with severe itching of the skin .

This medicine is available only with your doctor's prescription .

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

Dosage

This section provides information on the proper use of a number of products that contain fexofenadine. It may not be specific to Afexdine ODT. Please read with care.

You should always take this medicine with water. Do not take it with juice such as grapefruit, orange, or apple juice .

You should NOT take antacids that contain aluminum or magnesium hydroxide within 15 minutes of taking this medicine. If you are uncertain about this, ask your doctor or pharmacist .

For patients using the oral disintegrating tablet form of this medicine:

Make sure your hands are dry. Do not push the tablet through the foil backing of the package. Instead, gently peel back the foil backing and remove the tablet. Immediately place the tablet on top of the tongue. Do not chew or break the tablet. The tablet will dissolve in seconds, and you may swallow it with your saliva. You may drink a glass of water after the tablet has dissolved. Always take this tablet on an empty stomach .

Shake the oral liquid well before using it. Measure the liquid with a marked measuring spoon, oral syringe, or medicine cup .

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For symptoms of hay fever: For oral dosage form (capsules, tablets): Adults and children 12 years of age and older—60 milligrams (mg) two times a day, or 180 mg once a day. Children 6 to 11 years of age—30 mg two times a day. Children 4 to 6 years of age—Use and dose must be determined by your doctor . Children and infants up to 4 years of age—Use is not recommended . For oral dosage form (disintegrating tablets): Children 6 to 11 years of age—30 milligrams (mg) two times a day, on an empty stomach. Children 4 to 6 years of age—Use and dose must be determined by your doctor . Children and infants up to 4 years of age—Use is not recommended . For oral dosage form (suspension): Children 4 to 11 years of age—30 milligrams (mg) or 5 milliliters (mL) two times a day. Children younger than 4 years of age—Use and dose must be determined by your doctor .

For symptoms of chronic hives: For oral dosage form (capsules, tablets): Adults and children 12 years of age and older—60 milligrams (mg) two times a day, or 180 mg once a day. Children 4 to 11 years of age—30 mg two times a day. Children younger than 4 years of age—Use and dose must be determined by your doctor . For oral dosage form (disintegrating tablets): Children 4 to 11 years of age—30 milligrams (mg) two times a day, on an empty stomach. Children younger than 4 years of age—Use and dose must be determined by your doctor . For oral dosage form (suspension): Children 4 to 11 years of age—30 milligrams (mg) or 5 milliliters (mL) two times a day. Children 6 months to 4 years of age—15 mg or 2.5 mL two times a day. Children younger than 6 months of age—Use and dose must be determined by your doctor .

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include dry mouth, dizziness, or drowsiness.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Afexdine ODT dosage information

Side effects

The most common side effects associated with Afexdine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Very young children are usually more sensitive to the effects of this medicine. Before giving any of these combination medicines to a child, check the package label very carefully. Some of these medicines are too strong for use in children. If you are not certain whether a specific product can be given to a child, or if you have any questions about the amount to give, check with your health care professional, especially if it contains:

Antihistamines—Nightmares, unusual excitement, nervousness, restlessness, or irritability may be more likely to occur in children taking antihistamines. Decongestants (e.g., ephedrine, phenylephrine, pseudoephedrine—Increases in blood pressure may be more likely to occur in children taking decongestants. Iodides (e.g., calcium iodide and iodinated glycerol)—These medicines pass into the breast milk and may cause unwanted effects, such as underactive thyroid, in the baby. Narcotic antitussives (e.g., codeine, dihydrocodeine, hydrocodone, and hydromorphone)—Breathing problems may be especially likely to occur in children younger than 2 years of age taking narcotic antitussives. Also, unusual excitement or restlessness may be more likely to occur in children receiving these medicines. Salicylates (e.g., aspirin)—Do not give medicines containing aspirin or other salicylates to a child or teenager with a fever or other symptoms of a virus infection, especially flu or chickenpox, without first discussing its use with your child's doctor. This is very important because salicylates may cause a serious illness called Reye's syndrome in children with fever caused by a virus infection, especially flu or chickenpox. Also, children may be more sensitive to the aspirin or other salicylates contained in some of these medicines, especially if they have a fever or have lost large amounts of body fluid because of vomiting, diarrhea, or sweating.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

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To determine the proportion of children with herpes simplex encephalitis (HSE) displaying TLR3 deficiency, the extent of TLR3 allelic heterogeneity, and the specific clinical features of TLR3 deficiency. The concentrations of S-25-OH-D3 were significantly lower in the mothers than in the non-pregnant controls in winter, but the difference was not significant in summer. This approach is based on Nucleofection and the protocol has been optimized to maintain maximum capability for cell activation after transfection. 2086 patients who underwent 2499 inguinal hernia repairs were identified. Scheduling prioritized patients in emergency department laboratories. Testicular torsion in men more than 21 years old seems to be as common as in prepubertal boys, accounting for 26 per cent of our cases. Plasma renin and angiotensin II subsequently did increase upon chronic irbesartan treatment. No hand ischemic complications have been observed in this group. Pooled estimates were calculated for overall and subgroup analyses. Generation of this import intermediate was dependent on a mitochondrial membrane potential, mitochondrial surface proteins, and was stimulated by proteins that could be released from the ribosomes by high salt.

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A primary biochemical effect of Wnt-1 signaling is the stabilization of cytoplasmic (beta)-catenin which, in association with transcription factors of the Lef/tcf family, regulates gene expression. Detection of prednisolone in vitreous following systemic administration. Etodolac is a nonsteroidal anti-inflammatory drug which has been demonstrated to protect liver against fibrosis. Lung SEMCAP-2 and SEMCAP-1(GIPC) are potential partners for both GAIP and M-SemF. Together, these results indicate that the WS region is associated with large, duplicated blocks of DNA on human chromosome 7q11.23 as well as the corresponding genomic regions of other nonhuman primates. Malnutrition as assessed by nutritional risk index is associated with worse outcome in patients admitted with acute decompensated heart failure: an ACAP-HF data analysis. The authors feel that vested interests have a history of trying to use earlier state CON regulations to control their turf, limit competition, and consequently stifle innovation.

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Correlations between RBCs age and duration of intubation, intensive care unit, or hospital stay, and base excess at the first postoperative morning were also analyzed. In our opinion current human papillomavirus testing is of little clinical use to the practitioner. To evaluate the usefulness of diffusion- weighted MRI (DWI) in the detection and staging of liver fibrosis and inflammation. To broaden the scope of what is relevant in such investigations is to increase the amount of data scientists must reckon with. The patients included 21 United States residents and most commonly were young women with a subacute illness characterized by persistent, painless cervical adenopathy with or without fever. Procurement of lungs for transplantation following donation after circulatory death: the Alfred technique. The pedigree is suggestive of an autosomal dominant mode of inheritance. The number of image classes, number of object types, and the characteristics of the object-feature mixture models are inferred nonparametrically. Use of antibiotics in industrial fermentations is not an applicable option to maintain plasmid stability. When the cell lines were cultivated as confluent cultures, a 3- to 10-fold amplification of the HPV genomes per cell was induced.

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The impact of comorbidities on patients with advanced head and neck cancer treated with major surgery has not been reported before. pylori seropositivity among Italian healthy adults and points to sex, age, BMI and sociocultural class as persisting determinant features of H. Prevention of exposure to allogeneic blood transfusion during surgery is an important financial issue when recombinant human erythropoietin (rHuEPO) is used in addition to preoperative blood donation. RET is the major gene associated to Hirschsprung disease (HSCR) with differential contributions of its rare and common, coding and noncoding mutations to the multifactorial nature of this pathology. Poincare plots with lags of 1 and 6 were constructed, and the ratio of albenza cost at rite aid the minor axis to major axis (SD1/SD2) and the area of Poincare plots were calculated for each lag.

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