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Adalate (Nifedipine)

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Adalate is a drug that performs by relaxing the muscles inside the heart and blood vessels in order to enable easier blood flow. This enables the heart to have an easier time pumping blood. The active ingredient is nifedipine and it a part of a class of drugs called calcium channel blockers. The primary use of this medication is to help stop chest pain (angina) and help treat high blood pressure problems (hypertension). In addition to this it can also be used in order to heighten the supply of oxygen and blood to the heart and help with a specific blood circulation condition called Raynaud’s phenomenon.

Other names for this medication:
Adipine, Amarkor, Anpect, Belnif, Calcheck, Calcibloc, Calcigard, Chronadalate, Citilat, Coracten, Cordilat, Emaberin, Fenamon, Ficard, Hexadilat, Lemar, Macorel, Nefelid, Nidilat, Nidipine, Nifatenol, Nifecap, Nifecard, Nifeclair, Nifedalat, Nifedel, Nifediac, Nifedigel, Nifedin, Nifedip, Nifedipine, Nifedipino, Nifin, Noviken, Ospocard, Pabalat, Sidalat, Siopelmin, Valni, Xepalat

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Adalate. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Adalate and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of nifedipine in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems which may require caution and an adjustment in the dose for patients receiving nifedipine.

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Urban and rural patterns of bicycle helmet use: factors predicting usage. Controlling for age, gender, severity of internalizing behavior problems, social competence, family psychopathology, and parent-child relationship quality (assessed by parent report), an ODD diagnosis, with or without comorbid ADHD, was associated with increased likelihood of prior victimization (but not nonvictimization) trauma. Prostaglandin E2 EP receptors as therapeutic targets in breast cancer. Managed care introduced two changes from the fee-for-service (FFS) delivery system currently used by injured workers in Washington State: experience- rated capitation and a primary occupational medicine delivery network. Every year, tens of thousands of patients die from this condition, many of them suddenly. We observed significant haplotype-sharing within this new interval among three unrelated American PGL families, strongly suggesting that they originated from a common ancestor.

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Perioperative management of the patient with a coronary artery stent. Radioimmunoassay for antibodies to human skeletal muscle myosin in serum from patients with polymyositis. Myocardial oxygen consumption during dobutamine infusion in endotoxemic pigs. Glucocorticoid-induced impairment of long-term memory retrieval in rats: an interaction with dopamine D2 receptors. In 11 cases, an internal mammary chain lymph node was harvested. The Escherichia coli IncG and IncU plasmid incompatibility groups were assigned in 1980 and 1981, respectively.

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To define the functional role of the Rnd3 gene in the animal heart and investigate the associated molecular mechanism. Increasing ART use worldwide and persistently high ART multiple-birth rates in several countries highlight the need for strategies that encourage single-embryo transfer. Physiological changes of Salmonella typhimurium cells under osmotic and starvation conditions by image analysis. To account for these results quantitatively, we used difference-spectrum analysis to identify those frequency components of the targets that might form a basis for performing the visual discrimination task. The ability of subjects to discriminate between a smooth and a grooved surface was measured under conditions that are typically used in grating orientation tasks. Our results are important when considering the effectiveness of policies that aim to address the economic problems associated with disability for older people, suggesting that current policy in Ireland does xanax drug test not go far enough. In which journals do active researchers of palliative care publish their articles?.

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Intima-media thickness of carotid and cavernosal arteries and cavernosal peak systolic velocity (PSV) were investigated by color Doppler ultrasound. Vibrational spectroscopic studies and ab initio calculations of sulfanilamide. Angular momentum-induced circular dichroism in non-chiral nanostructures. Antibody-dependent cytotoxicity mediated by cells eluted from synovial tissues of patients with rheumatoid arthritis and juvenile rheumatoid arthritis. The incarceration period is an opportunity for oral health improvements in these young people through access to dental treatment services. The statistical analysis afforded by our approach revealed subtle but reproducible differences in protein expression and protein phosphorylation between embryonic stem cells and induced pluripotent cells. The development of selective histone deacetylase (HDAC) inhibitors rocaltrol cost with anti-cancer and anti-inflammatory properties remains challenging in large part owing to the difficulty of probing the interaction of small molecules with megadalton protein complexes. Trials of longer duration are also required, particularly because information about the side-effects of long-term use of clioquinol is limited.

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Acute renal failure following mucosal administration of povidone iodine. Angiogenesis involves proliferation of capillary endothelial cells and formation of lumen-containing tube-like structures. The subjects were women at least 55 years of age with newly diagnosed Stage I or II breast cancer. Odds ratio was done to determine association between independent variables and acute respiratory infections by using logistic regression analysis. The message involves many personal factors on the part of the communicator and on the part of the audience. To evaluate outcomes of the endothelial progenitor cell (EPC) capture stent in patients on chronic anti-vitamin K (AVK) regimen, requiring percutaneous coronary intervention (PCI). International noninterventional study of acarbose treatment in patients with type 2 diabetes mellitus. New technologies for studying the microbiology, immunology, and pathogenesis of tuberculosis in nonhuman primates have greatly expanded the capabilities of this model for basic and translational studies, including the development and testing of new treatment and prevention strategies for what schedule of drug is xanax tuberculosis. Fibroblast growth factor (FGF)-21 has been recently characterized as a potent metabolic regulator, but the physiological role of FGF-21 remains poorly understood. Combined treatment with endothelin- and PAF-antagonists reduces posttransplant lung ischemia/reperfusion injury.

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Adverse effects of childhood lead poisoning: the clinical neuropsychological perspective. The absence of high- resolution structural data has hampered our understanding of RNAP mechanism. The choriocapillaris in the bovine as a freely communicating network is subdivided into star-shaped areas of roughly hexagonal form. Taken together, our data suggest a model for the regulation of C/EBPbeta expression in which v-Myb stimulates the synthesis of C/EBPbeta by enhancing an autoregulatory loop acting on the C/EBPbeta promoter. Sprayed cells and polyelectrolyte films for biomaterial functionalization: the influence of physical PLL-PGA film treatments on dental pulp cell behavior. The sequential development of the fetal lesions was studied and the lesions compared with those in both naturally occurring and experimentally induced infections of the dams which either aborted or carried to term.

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We then found that Hes1 directly bound to the promoter region of the FMS-like tyrosine kinase 3 (FLT3) gene and downregulated the promoter activity. Dehydration could be considered as a risk factor for development of CVST in appropriate situations. Preoperative insertion of an IABP was associated with a shorter stay in intensive care, decreased incidence of postoperative dialysis and acute heart failure, and a reduction in postoperative mortality compared with OPCAB alone. Speciation of Cr(III) and Cr(VI) in environmental samples by solid phase extraction on Ambersorb 563 resin. These data provide insight into the apparent stabilization of CTx B relative to SLTx B.

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Immobilization of antibodies on biosensing devices by nanoarrayed self-assembled monolayers. Assessment of some tools for the characterization of the human osteoarthritic cartilage proteome. More insidious disturbances of mitochondrial homeostasis may result from impaired balance in the pathways that promote mitochondrial repair (biogenesis) and pathways that remove dysfunctional mitochondria (mitophagy). Evidence-based medicine and clinical trials in pediatric orthopaedics. This study has been re-evaluated and an additional group of 20 patients consecutively operated on in 2002/2003 has been added. Following thorough training and education on the purpose of continued antihypertensive therapy, the patient could be discharged with a normotensive blood pressure profile. Scalable fabrication of polymer temovate gel dosage membranes with vertically aligned 1 nm pores by magnetic field directed self-assembly.

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