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Acyclovir is approved by the Food and Drug Administration as a prescription drug that is commonly used as a topical, injectable, and oral treatment for genital herpes and cold sores. Herpes viral infections are very common. Genital herpes refers to a sexually transmitted disease (STD).

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Acyclovir Topical (for the skin) is an antiviral medicine that is used to treat skin symptoms caused by the herpes virus.

Acyclovir Topical cream is used to treat cold sores on the lips and face.

Acyclovir Topical ointment is used to treat genital herpes lesions.

There is no cure for herpes and acyclovir will not prevent you from developing symptoms in the future.


Take Acyclovir exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Start taking Acyclovir as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters).

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Acyclovir doses are based on weight (especially in children and teenagers). Your dose needs may change if you gain or lose weight.

Drink plenty of water while you are taking Acyclovir to keep your kidneys working properly.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses may increase the risk of your virus becoming resistant to medication.

Lesions caused by herpes viruses should be kept as clean and dry as possible. Wearing loose clothing may help to prevent irritation of the lesions.

Store at room temperature away from moisture and heat.

Detailed Acyclovir dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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