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Acuvin (Tramadol)
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Acuvin

Acuvin is a narcotic-like pain relieving oral medicine that is used as a treatment for moderate to severe pain in adults. This medication must be prescribed by a doctor and is available by prescription only.

Other names for this medication:
Adamon, Anatram, Anazac, Arodol, Combitram, Cradol, Dolomed, Domadol, Medol, Muzox, Nomadol, Sigmadol, Spasteez, Tragesic, Tramache, Tramafen, Tranat, Trandol, Trapain, Trapidol, Trydol, Ubitdol, Vardol, Vegadol, Victadol

Similar Products:
Rulide, Effexor, Sinequan, Xenical, Provera, Hecobac, Zobenda, Amlodin, Retop, Zidmin, Flossac, Phyne, Broncophyl, Formet,

Also known as: Tramadol

Description

Acuvin (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

Acuvin is used to treat moderate to severe pain in adults.

The extended-release form of tramadol (Acuvin ER) is for around-the-clock treatment of pain. Acuvin ER is not for use on an as-needed basis for pain.

Dosage

Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Acuvin: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Acuvin is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Acuvin dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.

Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Throw away any medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Acuvin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Acuvin if you are allergic to tramadol, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Acuvin should not be given to a child younger than 12 years old. Acuvin ER should not be given to anyone younger than 18 years old.

Do not give Acuvin to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Acuvin. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

To make sure Acuvin is safe for you, tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use tramadol during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using tramadol if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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Improvement of lichenysin production in Bacillus licheniformis by replacement of native promoter of lichenysin biosynthesis operon and medium optimization. Trial-by-trial criterion setting is obtained when subjects respond faster in trials following a word trial than in trials following nonword trials - irrespective of the lexicality of the current trial. In the present report we show that most but not all of the proteolytic activities of partially purified 20S/26S proteasomes from skeletal muscle of rats increase after induction of Diabetes mellitus. Voltage-sensitive fluorescence of amphiphilic hemicyanine dyes in a black lipid membrane of glycerol monooleate. Use of artifiial bone in lateral interbody fusion of the lumbar spine: a prospective radiographic study. Secondary peritonitis is still associated with high mortality, especially when multiorgan dysfunction complicates the disease.

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We studied the effect of MgADP on the mechanical interaction of actomyosin in cardiac and skeletal muscles using an in vitro motility assay. The middle ear of guinea pigs was first damaged on one side (inflicting a subtotal perforation of the tympanic membrane, dislocation of the incudo-stapedial joint followed by otitis media) and the animals were then exposed to a specified narrow-band noise. All clinical trials that were available prior to submission of this manuscript for publication, including unpublished reports, were reviewed. Non-insulin-dependent diabetes mellitus in young patients with autosomal dominant inheritance. The effect of psychotropic substances on synaptosomal uptake of gamma-aminobutyric H3-acid and the activity of Na,K-ATPase. We reviewed the records of a single surgeon, consecutive series of patients treated with 3.5 cm artificial urinary sphincter cuff placement from September 2009 to August 2013. These products irreversibly inactivated the dihydrolipoamide dehydrogenase from Trypanosoma cruzi (T cruzi LADH), depending on: the Phen structure, peroxide type, activated cyt c, incubation time and presence of an antioxidant. The transcription level of c-Ha-ras oncogene and the content of P21ras in those exposed to chrysotile treated in advance with three kinds of chemicals mentioned above were significantly lower than those in untreated. There were differential proteins in PKC epsilon complexes during the different stages of POH.

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Free radicals, oxidative stress, and DNA metabolism in human cancer. The angular intensity functions are calculated for planes that are parallel or perpendicular to the plane of the tubules. In addition to anti-inflammatory management of AA amyloidosis, specific treatment strategies may possibly become available in the future. We have examined the expression of a number of genes in the anteriorised embryos. With ongoing refinement of imaging approaches and brain delivery methods, MRI-based techniques for molecular-level neuroscientific investigation will fall increasingly within reach. Excessive fluoride inducing calcium overload and apoptosis of ameloblasts. Herein, we designed and synthesized a FRET-based ratiometric probe to detect HNO in living cells.

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Improved protocol for using avian red blood cells as substrates for the polymerase chain reaction. Two forms of nonglycosylated recombinant alpha2AP were expressed, isolated and characterized: (1) wild-type, which was analogous to native alpha2AP, and (2) a mutant form, which had Ala substituted for the reactive-site Arg364. Methods used to correct these effects and obtain a uniform, linear and constant relationship between concentration and grey level are described. To gather experimental data on whether Dodick laser phacolysis leads to corneal or scleral burns. MicroRNAs (miRNAs) are endogenous short non-coding RNAs that repress post-transcriptional regulation of gene expression, while embryonal central nervous system tumors are the foremost cause of mortality in children suffering from a neoplasm.

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Effectiveness of immune therapy combined with chemotherapy on the immune function and recurrence rate of cervical cancer. This constant adaptation of the actin cytoskeleton appears, from a number of approaches, to result from a continuous cycle of assembly and disassembly of filaments leading to continuous adaptation of the actin cytoskeleton. In essence, risk assessment decisions in this context are fundamental as they form the basis for risk management options, which in turn should reduce health risks posed by resistant microorganisms. This comorbid diagnosis of stuttering was found to contribute to the abnormal overactivity seen in the group of adults who clutter in the right ventral premotor cortex and right anterior cingulate cortex. A reliable and sensitive enzyme immunoassay method for measuring 8-isoprostaglandin F2 alpha: a marker for lipid peroxidation after experimental brain injury.

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