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Acloriv (Acyclovir)

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Acloriv is an antiviral medicine. It helps in treating viral infections like herpes labialis, herpes simplex, shingles, genital herpes infection, and chickenpox. It prevents the multiplication of virus in human cells and therefore helps in clearing the infection.

Other names for this medication:
Aclovir, Acvirall, Acycloguanosine, Acyclor, Acyclovir, Acylab, Alovir, Cevirin, Cloviderm, Clovir, Clovirax, Clyvir, Cutivir, Cycloex, Cyclopiz, Docvir, Herperax, Herpex, Kayvir, Nisivir, Ocuvir, Ophtrhovir, Rivol, Rowapil, Setuvir, Trikase, Virex, Viroxit, Zovir, Zoylex

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Also known as: Acyclovir


Acyclovir belongs to the family of medicines called antivirals, which are used to treat infections caused by viruses. Usually these medicines work for only one kind or group of virus infections.

Acyclovir is used to treat the symptoms of chickenpox, shingles, herpes virus infections of the genitals (sex organs), the skin, the brain, and mucous membranes (lips and mouth), and widespread herpes virus infections in newborns. Acyclovir is also used to prevent recurrent genital herpes infections. Although acyclovir will not cure herpes, it does help relieve the pain and discomfort and helps the sores (if any) heal faster.

Acyclovir may also be used for other virus infections as determined by your doctor. However, it does not work in treating certain virus infections, such as the common cold.

Acyclovir is available only with your doctor's prescription.


Patient information about the treatment of herpes, chickenpox, or shingles is available with this medicine. Read it carefully before using this medicine.

Acyclovir is best used as soon as possible after the symptoms of herpes infection or shingles (for example, pain, burning, blisters) begin to appear.

If you are taking acyclovir for the treatment of chickenpox, it is best to start taking acyclovir as soon as possible after the first sign of the chickenpox rash, usually within one day.

Acyclovir capsules, tablets, and oral suspension may be taken with meals or on an empty stomach.

Acyclovir is best taken with a full glass (8 ounces) of water.

If you are using acyclovir oral suspension, use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your herpes infection, chickenpox, or shingles, keep taking acyclovir for the full time of treatment, even if your symptoms begin to clear up after a few days. Do not miss any doses. However, do not use this medicine more often or for a longer time than your doctor ordered.

If you are taking acyclovir capsules, tablets, or oral suspension, you should drink plenty of water to avoid becoming dehydrated.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules, oral suspension, or tablets): For treatment of genital herpes: Adults and children 12 years of age and older—200 milligrams (mg) five times a day for ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For prevention of recurrent outbreaks of genital herpes infections: Adults and children 12 years of age and older—200 to 400 mg two to five times a day for five days or up to twelve months, depending on how often your outbreaks of infection occur. Children up to 12 years of age—Use and dose must be determined by the doctor. For treatment of chickenpox: Adults and children who weigh over 88 pounds (40 kilograms)—800 mg four times a day for five days. Children 2 years of age and older and weighing 88 pounds (40 kilograms) or less—Dose is based on body weight and must be determined by the doctor. The usual dose is 20 mg per kilogram (kg) of body weight, up to 800 mg, four times a day for five days. Children up to 2 years of age—Use and dose must be determined by the doctor. For treatment of shingles: Adults and children 12 years of age and older—800 mg five times a day for seven to ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For injection dosage form: For treatment of herpes of the brain, genitals, or mucous membranes, or for the treatment of shingles: Adults and children 12 years of age and older—Dose is based on body weight and must be determined by the doctor. The usual dose is 5 to 10 mg of acyclovir per kg (2.3 to 4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period, and repeated every eight hours for five to ten days. Children up to 12 years of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg to 20 mg of acyclovir per kg (4.5 mg to 9.1 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for seven to ten days. For treatment of widespread herpes virus infection in newborns: Infants from birth to 3 months of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg of acyclovir per kg (4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for ten days.


An overdose of Acloriv Topical is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Acloriv dosage information

Side effects

The most common side effects associated with Acloriv are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Acloriv if you are allergic to acyclovir or valacyclovir (Valtrex).

To make sure Acloriv is safe for you, tell your doctor if you have:

kidney disease; or a weak immune system (caused by disease or by using certain medicine).

Tell your doctor if you are pregnant or breastfeeding.

Herpes can be passed to your baby during childbirth if you have a genital lesion when your baby is born. If you have genital herpes, it is very important to prevent herpes lesions during pregnancy. Take your medicine as directed to best control your infection.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Acloriv should not be given to a child younger than 2 years old.

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A 56-year-old female presented with chronic subdural hematoma due to spontaneous (primary) intracranial hypotension (SIH). In the future, these techniques may be combined with pharmacological strategies, such as presurgical erythropoietin therapy or red cell substitutes, to reduce further the need for allogeneic blood. A Text Message Delivered Smoking Cessation Intervention: The Initial Trial of TXT-2-Quit: Randomized Controlled Trial. After the isolated mouse common carotid arteries were perfused with HL-60 cells, the unbound leukocytes were washed away and the number of adherent cells in every single field was counted under a microscope. Assessment of the severity of coronary artery stenosis by the ratio of the regional washout rate determined by adenosine triphosphate stress Tl-201 SPECT. Significant negative correlations of the mood and feelings questionnaire scores with mean ReHo values in the medial frontal gyrus and the right middle frontal gyrus in PBD-depression patients were observed. The localization of CA in the eyes of CA II-deficient mice and of normal mice was studied by the cobalt-phosphate histochemical method. Naringin at the concentration of 10-6 mol/L can enhance the proliferation and osteogenic differentiation of BMSCs.

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New molluscan larval form: brooding and development in a hydrothermal vent gastropod, Ifremeria nautilei (Provannidae). Effect of adrenolytic agents (alpha and beta blockaders), of a monoamine oxidase inhibitor and of an SH donor (Agr 307) on the serum glycuronidase increase induced by adrenaline infusion. We feel that intracoronary Wiktor stent implantation via the brachial approach is feasible. We used a standardized questionnaire to survey health-care providers in 22 PICT for information on the epidemiology of HIV infection and strategies used during 2004 to prevent MTCT of HIV infection in their country. Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis (Mtb) that affects millions of people worldwide. There are several small-molecule inhibitors of tyrosine kinase activity of VEGF receptors in clinical trials. In the present chapter, we summarize current evidence that CTxB associates with and cross-links lipid rafts, discuss how CTxB binding modulates the architecture and dynamics of membrane domains, and describe the functional consequences of this cross-linking behaviour on toxin uptake into cells via endocytosis. Receptor-mediated gene delivery has been reported for a number of different receptor systems although the intracellular fate of such systems has not been systematically investigated. An underrecognized complication of diabetic patients: Isolated muscle necrosis. Attitudes toward women dental students among male dental students and faculty in 1976 and 1996.

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The prevalence of dental caries was higher in immigrant children than in autochthonous children. Enantioseparation of these compounds has revealed rapid on-column enantiomerization. In Entamoeba, however, these genes are located almost exclusively on extrachromosomal circular DNA molecules with no clear evidence so far of a chromosomal copy. There is considerable evidence that judgment is constrained to additive integration of information. This leads to easier and faster surgery, potentially decreasing graft damage due to excessive fluidics and unnecessary manipulation. Therefore, both fungi are suitable candidates for the further development of tools that aim to control host-seeking or resting mosquitoes using entomopathogenic fungi. Association of the PIK3R1 SNP rs1550805 with serum leptin and body fat may reflect a diminished ability of PI3K to signal via IRS1 or IRS2 in response to leptin.

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Analysis of artificially matured untreated cuticle yielded moieties related to phenols and alkylated substituents, pyridines, pyrroles and possibly indenes (derived from chitin). This requires further studies with regard to the adaptation of An. Early exposure to peanut allergens, whether in utero or through human breast milk, seems to increase the risk of developing peanut allergy. As data volumes increase through effective high throughput screening, conventional interrogation methods become less appropriate and are being augmented by newer computing techniques referred to as knowledge mapping or database mining. These features suggested that mesangial cells played an important role in the age-related expansion of the mesangial region and thickening of the GBM. The pathologic correlates of many cases with positive ABR remain unknown. Can virtual chromoendoscopy measure up to histology in early gastric cancer?. In conclusion, patients with acute infectious enterocolitis present a marked loss of endointestinal albumins in the acute stage of the disease, with a return to normal values in convalescence.

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The sample consisted of 58 women with breast cancer receiving chemotherapy and registered in the public oncology ambulatory of Aracaju-Sergipe. The apertures are directly fabricated on a metal-coated CMOS imaging sensor. Genotype alone does not predict the clinical course of SFTPC deficiency in paediatric patients. He summarizes basic indications for insulin treatment also beyond the sphere of diabetology. Quantitative falsification of instrumental variables assumption using balance measures. Diabetes, obesity, and metabolic syndrome are becoming epidemic both in developed and developing countries in recent years. Partitioning coefficients of pyrene between copolymer micelles and water were also determined and increase in magnitude with increasing epsilon-caprolactone content of the copolymer.

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In addition, a significantly higher number of patients in the real rTMS group regained mobility at the post-test assessment compared with the corresponding number of patients in the sham rTMS group. Comparison of three immunodiagnostic assays for antemortem detection of Mycobacterium bovis stimulation in domestic cats. The checking of the vial-shaking test for the detection of the freezing of toxoid-based vaccines. Interaction of a soluble fibroblast surface protein with fibrin. In applied research fields like robotics the aim is to build biomimetic hand structures, or in prosthetics to design more performant underactuated replacement hands. Variations in the promoter region of the glutaminase gene and the development of hepatic encephalopathy in patients with cirrhosis: a cohort study. Construct validity was investigated by testing 10 hypotheses: limitations in climbing stairs according to the Climbing Stairs Questionnaire will be greater in lower-limb amputees who: (1) are older, (2) have a vascular cause of amputation, (3) have a bilateral amputation, (4) have a higher level of amputation, (5) have more comorbid conditions, (6) had their rehabilitation treatment in a nursing home, and (7) climb fewer flights of stairs. Statins have been shown to direct inhibitory activity against a range of Zygomycetes molds, both in vitro and in vivo.

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Lactoferrin (LF), a human serum protein, strongly inhibited the adherence of Plasmodium falciparum-infected erythrocytes (PE) to immobilized chondroitin sulfate A (CSA)-conjugated albumin at a concentration of 100 microg/mL and blocked the PE binding to CD36-expressing Chinese hamster ovary (CHO) cells, as well as immobilized CD36 at concentrations of 5 microg/mL and 100 microg/mL, respectively. This region of PAI-2 corresponds to exon 3 of the gene sequence thought to be critical for PAI-2 functions. As spondylolisthesis develops and progresses, the SPECT scan again becomes positive. This document is a prerequisite to obtain certification of the quality system or laboratory accreditation, according to the International Standard ISO 29000 series or the European Standard EN 45001, respectively. To clarify the mechanism of covalent binding between human serum albumin (HSA) and drugs containing thiol groups, we studied the interactions between HSA and bucillamine (BA) and its derivatives. Consistent with demographic data collected at the Addictions Foundation of Manitoba, it appears that video lottery terminals play a major role in the type of problem gambling experience seen in Canadian settings.

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We examined the effect of visual-vestibular exercises in two children on dynamic visual acuity (DVA), critical print size (CPS) and reading acuity (RA) using an ABA design. Such a speed of convergence allows the proposed algorithm to easily adapt to a subject of interest without any additional artificial data preparation prior the algorithm execution such in case of data enhancement technique. Medium-chain TAG attenuate hepatic oxidative damage in intra-uterine growth-retarded weanling piglets by improving the metabolic efficiency of the glutathione redox cycle. Subcellular localization is an important determinant of substrate and functional specificity for cyclin-cyclin dependent kinase (CDK) complexes. The inclusion of subject-specific muscle data resulted in changes in the model-predicted muscle forces and activations which agree with previously reported compensation patterns and match more closely the timing of electromyography for the plantar flexor and hamstring muscles. The other TLRs that are evolutionarily closely related and highly homologous are TLR7, TLR8, and TLR9. Prostate specific membrane antigen mRNA in blood as a potential predictor of biochemical recurrence after radical prostatectomy. The sequence of the rhesus monkey double homeodomain reveals significant sequence identity with the human 4q sequence. However, many parents who might have benefited from discipline counseling were less likely to receive it and more likely to report this as an unmet need.

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SHR and WKY were subjected to adrenalectomy or sham surgery at 12 wk and studied at 15 wk. PR3 protein was also detected in the parotid saliva of periodontitis patients, and PR3, but not human leukocyte elastase and cathepsin G, degraded intact Lf. After embryonic day 17, distribution of cells on surface of primary muscle fibres in mouse is non-random. Spongiotrophoblast at day 12 showed lectin reactivity similar to that of ectoplacental cone cells but at day 15 the reaction pattern indicated loss of N-acetylgalactosamine residues in the large, glycogen-rich cells. All patients (except one with recent injury) were asymptomatic for a long period before development of neck pain or myelopathy, despite obvious subluxation and kyphotic deformities at the C1-2 joint complex. In Chinese adolescents, bone mineral accretion at adolescence is not influenced by exercise, level of physical fitness and calcium intake. Theoretical study of the NLO responses of some natural and unnatural amino acids used as probe molecules. Type II restriction endonucleases (REases) are deoxyribonucleases that cleave DNA sequences with remarkable specificity. Perinatal variables and neonatal outcomes in severely growth restricted preterm fetuses. Three of the five patients had immediate postoperative urinary leakage at the proximal anastomosis, necessitating drainage, prolonged double-J stenting and/or nephrostomy diversion.

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Measurement of manganese content in various organs in rats with or without glucose stimulation. Four hundred randomly selected community pharmacies in the Commonwealth of Massachusetts. Palladium-catalyzed highly stereoselective synthesis of N-aryl-3-arylmethylisoxazolidines via tandem arylation of O-homoallylhydroxylamines. The amount of annealing correlates exactly dosage of norfloxacin in pediatric with the ability of ER to bind bimolecular EREs. Individuals who exhibited negative top-down coupling during early suppression attempts experienced fewer involuntary memory intrusions later on. Increased awareness of transfusion-related morbidity from allogeneic blood products has resulted in increased development and application of alternatives to allogeneic transfusion. The present results advance our understanding of microbial degradation of cellulose/pectin-rich biomasses in the natural environment, and offer a new tool for reduction of agricultural waste, which is important for sustaining circulatory societies.

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PCR and DNA sequencing were used to look for the FV gene mutations in the proband. Furthermore, we summarize the work done on human clock genes and their expression in peripheral tissues. Pretreatment of either population with mitomycin-C abolished synergy. The target population includes all Jordanian women living in high- and low-density neighborhoods. In ascidians we have identified the site of initiation of repetitive calcium waves as an accumulation of endoplasmic reticulum sandwiched between the plasma membrane and an accumulation of mitochondria. Transanal rectal resection with internal and external sphincterectomy showed usefulness in preserving bowel function and avoiding permanent colostomy. Activity in the monkey parietal reach region (PRR) reflects both spatial information and the effector (arm or eye) that will be used in an upcoming reach or saccade task. If these models are correct, patients with MCS may have, in addition to temporal fluctuations, a lower level of consciousness compared with fully conscious individuals.

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Percutaneous coronary intervention was performed after failure of thrombolysis and confirmed occlusion of the left anterior descending artery. Debate and argument: there are connections between brain and mind and it is important that Rett syndrome be classified somewhere. Hapten-directed spontaneous disulfide shuffling: a universal technology for site-directed covalent coupling of payloads to antibodies. However, the exact role of LFA-1 in DC adhesion and migration remains obscure. The impact of the above trials on the trend in percutaneous coronary intervention (PCI) volume for SIHD and ACS is not known. Fetal wounds lack the inflammatory infiltrate characteristic of adult wounds, and the fetal environment is not necessary for scarless healing to occur. Effects of a potent and specific P-glycoprotein inhibitor on the blood-brain barrier distribution and antinociceptive effect of morphine in the rat. Highly efficient perovskite solar cells with tunable structural color. It leads to the specification of a threshold quantile autoregression (TQAR) model, which captures tricor dosage nonlinear dynamics by allowing lag effects to vary across quantiles of the distribution as well as with previous population levels.

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Anatomy, epidemiology, clinical evaluation, and treatment of these injuries are described in this review. Use of ultrasonic baths can be a successful means for improving denture hygiene among older people in long-term care with and without dementia. Maternal vitamin D status, prolonged labor, cesarean delivery and instrumental delivery in an era with a low cesarean how many maxolon tablets can you take rate. The effect of metapopulation dynamics on the survival and spread of a novel, conspicuous prey. Nitric oxide production in the basal forebrain is required for recovery sleep.

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