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Aceclofenac

Aceclofenac is used alone or in combination with other medications to treat high blood pressure. Aceclofenac is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It makes blood flow more smoothly by preventing the production of certain natural chemicals that tighten the blood vessels.

Other names for this medication:
Aceclofenac, Acertil, Acerycal, Agulan, Armix, Asyntilsan, Bionoliprel, Biprel, Bipreterax, Cardipen, Coveram, Coverene, Covinace, Domanion, Dorover, Indapril, Inopil, Midopril, Noliprel, Pendoril, Pendrex, Perindal, Perindan, Perindo, Perindox, Prestance, Preterax, Prexanil, Provinace, Reaptan, Stopress, Teraxans, Vectoryl, Vidotin

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Description

Aceclofenac is an angiotensin-converting enzyme (ACE) inhibitor. It works by blocking ACE, an enzyme involved in narrowing blood vessels and causing sodium and fluid retention by the kidneys. This causes blood vessels to relax, allowing blood to flow more freely and at a lower pressure, and increasing the heart's ability to pump blood in some types of heart failure. Aceclofenac is also known as Coversyl, Perindopril, Acertil, Armix, Coverene, Coverex, Coversum, Prestarium, Prexanil, Prexum, Procaptan. Generic name of Aceclofenac is Perindopril. Brand name of Aceclofenac is Aceclofenac.

Dosage

Usual Adult Dose for Coronary Artery Disease:

Initial dose: 4 mg orally once a day for 2 weeks, then increase to maintenance dose as tolerated. Maintenance dose: 8 mg orally once a day Use: Treatment of patients with stable coronary artery disease to reduce the risk of cardiovascular mortality or nonfatal myocardial infarction.

Usual Adult Dose for Hypertension:

Initial dose: 4 mg orally once a day Maintenance dose: 4 to 8 mg orally per day in 1 or 2 divided doses Maximum dose: 16 mg/day Comments: In patients treated with a diuretic, consider reducing the diuretic dose prior to starting this drug.

Usual Geriatric Dose for Coronary Artery Disease:

Greater than 70 Years: Initial dose: -Week 1: 2 mg orally once a day -Week 2: 4 mg orally once a day, then increase to maintenance dose as tolerated. Maintenance dose: 8 mg orally once a day Use: Treatment of patients with stable coronary artery disease to reduce the risk of cardiovascular mortality or nonfatal myocardial infarction.

Usual Geriatric Dose for Hypertension:

Initial dose: 4 mg orally per day in 1 or 2 divided doses Comments: Experience with doses above 8 mg is limited; administer with careful blood pressure monitoring and dose titration.

Detailed Aceclofenac dosage information

Overdose

If you overdose Aceclofenac and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Aceclofenac are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Aceclofenac if you are allergic to perindopril or if:

you have hereditary angioedema; you recently took a heart medicine called sacubitril; or you are allergic to any other ACE inhibitor, such as benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, quinapril, ramipril, or trandolapril.

Do not take Aceclofenac within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).

If you have diabetes, do not use Aceclofenac together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking Aceclofenac with aliskiren if you have kidney disease.

Tell your doctor if you have ever had:

kidney disease (or if you are on dialysis); liver disease; heart disease or congestive heart failure; diabetes; or a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis.

Do not use if you are pregnant, and tell your doctor right away if you become pregnant. Perindopril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

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