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Accupain (Tramadol)

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Accupain is an inexpensive drug used to treat moderate to severe pain in adults. This drug is more popular than comparable drugs. It is available in generic and brand versions. Accupain is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

Other names for this medication:
Acupain, Admadol, Bludol, Cadol, Combitram, Damadol, Hyperdol, Ivydol, Kevtram, Movon, Muzox, Neutram, Nictram, Opigesic, Paxmax, Ramax, Rybix, Sayodol, Siatram, Sigmadol, Spasteez, Standol, Traiz, Tramacip, Tramacon, Tramadex, Tramafen, Tramagesic, Tramatas, Tramazac, Tramex, Tramot, Tremtec, Tromar, Tromfil, Trugesic, Tryme, Ultracon, Urogendo, Victadol

Similar Products:
Glyburide, Trandate, Eriacta, Aldactone, Protonix, Clarinex, Eulexin, Allegra, Xenical, Danocrine, Mortrin, Lamepri, Angipec, Flucosept, Nexvir,

Also known as: Tramadol


Accupain ER is an pain medicine similar to an opioid. This medicine is used to treat moderate to severe pain.

The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.


Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Accupain: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Accupain is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Accupain dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Accupain are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Accupain if you are allergic to tramadol, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Accupain should not be given to a child younger than 12 years old. Accupain ER should not be given to anyone younger than 18 years old.

Do not give Accupain to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Accupain. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

To make sure Accupain is safe for you, tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use tramadol during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using tramadol if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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Participants with HFA/AS demonstrated no significant differences in performances with comparison participants when they had to control sensory or contextual information. Synthesis and properties of 2,3,4,6-tetra-O-benzyl-1-O-(N-benzyloxycarbonyidipeptidyl)-alpha- and -beta-D-glucopyranoses and 1-O-dipeptidyl-D-glucopyranoses. Developing optimal candidacy guidelines for these devices is a current goal. In this study, we combined two emerging technologies, pluripotent stem cell-derived cardiomyocytes and modern electrophysiology systems (impedance-based real-time) to assess the cytotoxicity of Brillantaisia nitens extract (BNE). Its receptor consists of a ligand-specific IL-31 receptor (IL-31R) subunit and a receptor chain that is shared with Oncostatin M (OSM), called OSM-Rbeta. Role of intracellular calcium in thermal allodynia and hyperalgesia in diabetic mice. A large number of low-molecular-weight heparin (LMWH) preparations are contending for superiority and their pharmacological properties need to be assessed. Neuroendocrine lung tumor with liver metastases and carcinoid syndrome.

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Stochastic nanopore sensors for the detection of terrorist agents: current status and challenges. In cell-free studies with BSA, incubation with Asc and copper resulted in glyoxal-hydroimidazolone formation, which was decreased by both AG and catalase. A work profile questionnaire was sent to 53 dietitians in Northern England. The new CRISPR-Cas system: RNA-guided genome engineering to efficiently produce any desired genetic alteration in animals. Beta-adrenergic blockade by propranolol potentiated in a minority of subjects the bronchoconstrictor response to deep inspiration.

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Infants and toddlers surviving past the age of 21 years can expect significant intellectual impairment if their radiation therapy was given at approximately 2 years of age. Nitric oxide pathway in hypertrophied heart: new therapeutic uses of nitric oxide donors. brasiliensis in response to the harsh environment of macrophages which may lead to adaptation and consequent survival of this pathogen. Twelve-month outcomes with a paclitaxel-eluting stent transitioning from controlled trials to clinical practice (the WISDOM Registry). The diagnosis of basal cell carcinoma represents a common and routine task for pathologists and dermatopathologists. Social and non-social cueing of visuospatial attention in autism and typical development. He had an additional expansive excision due to the histological diagnosis of myxoid liposarcoma at the initial surgery.

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In vivo affinity maturation of antibodies involves mutation of hot spots in the DNA encoding the variable regions. Six months later, she was found to have elevated serum thyroglobulin. Prenatal stress affects insulin-like growth factor-1 (IGF-1) level and IGF-1 receptor phosphorylation in the brain of adult rats. Factors influencing thrombus formation such as left atrial enlargement, atrial fibrillation and a prosthetic device are present after mitral porcine valve implantation and are indications for long-term anticoagulation therapy. The exact mechanism by which this link is elicited remains unclear. To describe temporal trends in the epidemiology, clinical management and outcome of candidemia in intensive care unit (ICU) patients.

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